Results 11 to 20 of about 1,862,769 (263)
Oncolytic viruses and pancreatic cancer. [PDF]
Cancer Treatment and Research Communications, 2022 BACKGROUND Today, the pancreatic cancer prognosis is poor and genetic technology is developing to treat various types of cancers. Scientists are actively looking for a new technique to design a therapeutic strategy to treat pancreatic cancer.
Vahideh Hamidi-Sofiani +5 more
semanticscholar +5 more sources
Oncolytic viruses in melanoma [PDF]
Frontiers in Bioscience-Landmark, 2022 Malignant melanoma recurrence remains heterogeneous in presentation, ranging from locoregional disease (i.e., local recurrence, satellites, in transit disease) to distant dermal and visceral metastases.
Camille Robinson +4 more
semanticscholar +4 more sources
Oncolytic effects of a novel influenza A virus expressing interleukin-15 from the NS reading frame. [PDF]
PLoS ONE, 2012 Oncolytic influenza A viruses with deleted NS1 gene (delNS1) replicate selectively in tumour cells with defective interferon response and/or activated Ras/Raf/MEK/ERK signalling pathway.
Marijke van Rikxoort +7 more
doaj +3 more sources
CRISPR-Cas9 as a Powerful Tool for Efficient Creation of Oncolytic Viruses [PDF]
Viruses, 2016 The development of oncolytic viruses has led to an emerging new class of cancer therapeutics. Although the safety profile has been encouraging, the transition of oncolytic viruses to the clinical setting has been a slow process due to modifications ...
Ming Yuan +3 more
doaj +2 more sources
Fusogenic Viruses in Oncolytic Immunotherapy [PDF]
Cancers, 2018 Oncolytic viruses are under intense development and have earned their place among the novel class of cancer immunotherapeutics that are changing the face of cancer therapy.
Jennifer Altomonte, Teresa Krabbe
core +4 more sources
New frontiers in oncolytic viruses: optimizing and selecting for virus strains with improved efficacy [PDF]
Biologics: Targets & Therapy, 2018 Kenneth Lundstrom PanTherapeutics, Lutry, Switzerland Abstract: Oncolytic viruses have demonstrated selective replication and killing of tumor cells.
Lundstrom K
doaj +3 more sources
Oncolytic viruses as anticancer vaccines [PDF]
Frontiers in Oncology, 2014 Oncolytic virotherapy has shown impressive results in preclinical studies and first promising therapeutic outcomes in clinical trials as well. Since viruses are known for a long time as excellent vaccination agents, oncolytic viruses are now designed as ...
Cristina-Ileana Ureche +9 more
core +5 more sources
Mesenchymal stem cells as carriers for systemic delivery of oncolytic viruses
European Journal of Pharmacology, 2020 Progress in genetic engineering led to the emergence of some viruses as potent anticancer therapeutics. These oncolytic viruses combine self-amplification with dual antitumor action: oncolytic (destruction of cancer cells) and immunostimulatory ...
Joanna Jazowiecka-Rakus +2 more
exaly +2 more sources
Oncolytic Viruses and Immune Checkpoint Inhibition: The Best of Both Worlds
Molecular Therapy: Oncolytics, 2019 Cancer immunotherapy and the emergence of immune checkpoint inhibitors have markedly changed the treatment paradigm for many cancers. They function to disrupt cancer cell evasion of the immune response and activate sustained anti-tumor immunity ...
Venkatesh Sivanandam +4 more
doaj +2 more sources