Results 31 to 40 of about 19,732 (239)
Recent advances in oncolytic virus therapy for hepatocellular carcinoma
Frontiers in Oncology, 2023 Hepatocellular carcinoma (HCC) is a highly refractory cancer and the fourth leading cause of cancer-related mortality worldwide. Despite the development of a detailed treatment strategy for HCC, the survival rate remains unsatisfactory.
Licheng Zhu +14 more
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Oncolytic viruses and cancer treatment
Klinicka onkologie, 2023 The fundamental difference between tumor and normal tissue growth is the emergence of the microenvironment with diminished or extinguished immunogenicity. One of the main functions of oncolytic viruses is the formation of such a microenvironment, which leads to a revival of immunological processes and loss of viability of cancer cells.
H, Španielová, R, Brdička
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Oncolytic virus delivery: from nano-pharmacodynamics to enhanced oncolytic effect [PDF]
, 2017 : With the advancement of a growing number of oncolytic viruses (OVs) to clinical development, drug delivery is becoming an important barrier to overcome for optimal therapeutic benefits.
core +1 more source
Oncolytic Viruses for Malignant Glioma: On the Verge of Success?
Viruses, 2021 Glioblastoma is one of the most difficult tumor types to treat with conventional therapy options like tumor debulking and chemo- and radiotherapy.
Yogesh R. Suryawanshi, Autumn J. Schulze
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Comprehensive assessment on the applications of oncolytic viruses for cancer immunotherapy
Frontiers in Pharmacology, 2022 The worldwide burden of cancers is increasing at a very high rate, including the aggressive and resistant forms of cancers. Certain levels of breakthrough have been achieved with the conventional treatment methods being used to treat different forms of ...
Richard Kolade Omole +14 more
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The current status of oncolytic viral therapy for head and neck cancer
World Journal of Otorhinolaryngology-Head and Neck Surgery, 2016 Objective: Cancer affects the head and neck region frequently and leads to significant morbidity and mortality. Oncolytic viral therapy has the potential to make a big impact in cancers that affect the head and neck. We intend to review the current state
Matthew O. Old +4 more
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Oncolytic Virotherapy: From Bench to Bedside
Frontiers in Cell and Developmental Biology, 2021 Oncolytic viruses are naturally occurring or genetically engineered viruses that can replicate preferentially in tumor cells and inhibit tumor growth. These viruses have been considered an effective anticancer strategy in recent years.
Ludi Yang +9 more
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Oncolytic viruses: finally delivering [PDF]
British Journal of Cancer, 2016 Oncolytic viruses can be found at the confluence of virology, genetic engineering and pharmacology where versatile platforms for molecularly targeted anticancer agents can be designed and optimised. Oncolytic viruses offer several important advantages over traditional approaches, including the following.
Seymour, Leonard W, Fisher, Kerry D
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Table_1_Clinical Trials of Oncolytic Viruses in Breast Cancer.docx
, 2021 Breast cancer is the second most common kind of cancer worldwide and oncolytic viruses may offer a new treatment approach. There are three different types of oncolytic viruses used in clinical trials; (i) oncolytic viruses with natural anti-neoplastic ...
André Koch (8770430) +3 more
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Fighting cancer with oncolytic viruses [PDF]
BMJ, 2006 Although gene therapy has huge potential for modern medicine, our enthusiasm for its powerful potential must not cloud our judgment about the dangers of using increasingly diverse, yet relatively untested, replicating ...
Yuti, Chernajovsky +2 more
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