Results 51 to 60 of about 1,862,769 (263)

Future Application of Oncolytic Viruses for Cancer Treatment [PDF]

, 2023
Cancer treatments have developed over the years. A particular improvement is the utilization of oncolytic viruses to treat cancers. Oncolytic viruses are one of the immunotherapeutic tools that potentially could provide good results and benefits to the ...
Jo, Juandy, Juandy Jo, Jevon Aaron Lesmana, Lesmana, Jevon Aaron   +3 more
core   +2 more sources

Recent advances in oncolytic virus therapy for hepatocellular carcinoma

Frontiers in Oncology, 2023
Hepatocellular carcinoma (HCC) is a highly refractory cancer and the fourth leading cause of cancer-related mortality worldwide. Despite the development of a detailed treatment strategy for HCC, the survival rate remains unsatisfactory.
Licheng Zhu, Licheng Zhu, Yu Lei, Yu Lei, Jia Huang, Jia Huang, Yahang An, Yanqiao Ren, Yanqiao Ren, Lei Chen, Lei Chen, Huangxuan Zhao, Huangxuan Zhao, Chuansheng Zheng, Chuansheng Zheng   +14 more
doaj   +1 more source

Effective Combination Immunotherapy using Oncolytic Viruses to Deliver CAR Targets to Solid Tumors

Science Translational Medicine, 2020
An effective combination immunotherapy using oncolytic viruses delivers de novo CD19 to promote CD19-CAR T cell therapy against solid tumors in mice.
Anthony K. Park, Y. Fong, Sang-In Kim, Jason Yang, J. Murad, Jianming Lu, Brook Jeang, W. Chang, N. Chen, Sandra H. Thomas, S. Forman, S. Priceman   +11 more
semanticscholar   +1 more source

Oncolytic virus delivery: from nano-pharmacodynamics to enhanced oncolytic effect [PDF]

, 2017
: With the advancement of a growing number of oncolytic viruses (OVs) to clinical development, drug delivery is becoming an important barrier to overcome for optimal therapeutic benefits.

core   +1 more source

Multi-Omics Analysis of Glioblastoma Cells’ Sensitivity to Oncolytic Viruses

Cancers, 2021
Simple Summary This study aims to uncover the contribution of interferon-dependent antiviral mechanisms preserved in tumor cells to the resistance of glioblastoma multiforme cells to oncolytic viruses.
A. Lipatova, A. V. Soboleva, V. Gorshkov, Julia A. Bubis, E. Solovyeva, G. Krasnov, D. V. Kochetkov, P. Vorobyev, I. Y. Ilina, S. Moshkovskii, F. Kjeldsen, M. Gorshkov, P. Chumakov, I. Tarasova   +13 more
semanticscholar   +1 more source

Measles virus causes immunogenic cell death in human melanoma [PDF]

, 2011
NoOncolytic viruses (OV) are promising treatments for cancer, with several currently undergoing testing in randomised clinical trials. Measles virus (MV) has not yet been tested in models of human melanoma.
Russell, S, Selby, P., Hadac, E., Donnelly, Oliver G, Jennings, V., Errington-Mais, F., Melcher, Alan A, Hadac, Elizabeth, Bond, J, Melcher, A.A., Bond, Jacquelyn, Selby, P, Bond, J., Peach, H., Vile, Richard, Steele, L., Vile, R., Hadac, E, Donnelly, O.G., Russell, Stephen, Harrington, K.J., Harrington, K, Peach, Howard, Steele, Lynette, Melcher, AA, Errington-Mais, Fiona, Harrington, Kevin, Russell, S., Phillips, Roger M., Pandha, H.S., Selby, Peter, Errington-Mais, F, Jennings, V, Scott, K, Phillips, RM, Phillips, Roger M, Scott, K., Pandha, Hardev, Vile, R, Jennings, Victoria, Steele, L, Pandha, H, Scott, Karen, Donnelly, OG, Peach, H   +44 more
core   +1 more source

Aptamers Enhance Oncolytic Viruses’ Antitumor Efficacy [PDF]

, 2022
Oncolytic viruses are highly promising for cancer treatment because they target and lyse tumor cells. These genetically engineered vectors introduce therapeutic or immunostimulatory genes into the tumor.
Dymova, Maya A., Richter, Vladimir A., Kuligina, Elena V., Elena V. Kuligina, Anna S. Kichkailo, Vladimir A. Richter, Maya A. Dymova, Kichkailo, Anna S.   +7 more
core   +1 more source

Adenovirus-Mediated Sensitization to the Cytotoxic Drugs Docetaxel and Mitoxantrone Is Dependent on Regulatory Domains in the E1ACR1 Gene-Region [PDF]

, 2012
Oncolytic adenoviruses have shown promising efficacy in clinical trials targeting prostate cancers that frequently develop resistance to all current therapies.
Halldén Gunnel, Miranda, Enrique, Maya Pineda, Hector, Oeberg, D, Cherubini Gioia, Zita Garate (130698), Maya Pineda Hector, Gunnel Halldén, Lemoine Nick R., Öberg, Daniel,, Nick R. Lemoine (130704), Lemoine, NR, Maya Pineda, H, Gunnel Halldén (130708), Nick R Lemoine, Gioia Cherubini, Daniel Öberg (130690), Halldén, G, Miranda Enrique, Garate Zita, Hector Maya Pineda, Öberg Daniel, Garate, Zita, Garate, Z, Zita Garate, Enrique Miranda (130684), Pineda, HM, Daniel Öberg, Halldén, Gunnel, Enrique Miranda, Öberg, D, Lemoine, Nick R, Hector Maya Pineda (130688), Cherubini, Gioia, Gioia Cherubini (130694), Miranda, E, Cherubini, G   +36 more
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Oncolytic Viruses and the Immune System: The Dynamic Duo

Molecular Therapy: Methods & Clinical Development, 2020
Oncolytic viruses (OVs) constitute a new and promising immunotherapeutic approach toward cancer treatment. This therapy takes advantage of the natural propensity of most tumor cells to be infected by specific OVs.
Ana Lemos de Matos, Lina S. Franco, G. McFadden   +2 more
semanticscholar   +1 more source

Oncolytic viruses and cancer treatment

Klinicka onkologie, 2023
The fundamental difference between tumor and normal tissue growth is the emergence of the microenvironment with diminished or extinguished immunogenicity. One of the main functions of oncolytic viruses is the formation of such a microenvironment, which leads to a revival of immunological processes and loss of viability of cancer cells.
H, Španielová, R, Brdička
openaire   +2 more sources