Results 41 to 50 of about 1,862,769 (263)
Infection of non-cancer cells: A barrier or support for oncolytic virotherapy?
Molecular Therapy: Oncolytics, 2022 Oncolytic viruses are designed to specifically target cancer cells, sparing normal cells. Although numerous studies demonstrate the ability of oncolytic viruses to infect a wide range of non-tumor cells, the significance of this phenomenon for cancer ...
Victor A. Naumenko +4 more
doaj +1 more source
Designing and Building Oncolytic Viruses [PDF]
Future Virology, 2017 Oncolytic viruses (OVs) are engineered and/or evolved to propagate selectively in cancerous tissues. They have a dual mechanism of action; direct killing of infected cancer cells cross-primes anticancer immunity to boost the killing of uninfected cancer cells.
Maroun, Justin +5 more
openaire +2 more sources
Global Challenges, 2023 Oncolytic viruses have found a good place in the treatment of cancer. Administering oncolytic viruses directly or by applying genetic changes can be effective in cancer treatment through the lysis of tumor cells and, in some cases, by inducing immune ...
Hai Zou, Xiao‐Zhou Mou, Biao Zhu
doaj +1 more source
The gamble between oncolytic virus therapy and IFN
Frontiers in Immunology, 2022 Various studies are being conducted on oncolytic virotherapy which one of the mechanisms is mediating interferon (IFN) production by it exerts antitumor effects.
Qingbo Li +10 more
doaj +1 more source
Pharmaceutics, 2022 Oncolytic virotherapy is a type of nanomedicine with a dual antitumor mechanism. Viruses are engineered to selectively infect and lyse cancer cells directly, leading to the release of soluble antigens which induce systemic antitumor immunity ...
Qing Ji +4 more
doaj +1 more source
Table_1_Clinical Trials of Oncolytic Viruses in Breast Cancer.docx [PDF]
, 2021 Breast cancer is the second most common kind of cancer worldwide and oncolytic viruses may offer a new treatment approach. There are three different types of oncolytic viruses used in clinical trials; (i) oncolytic viruses with natural anti-neoplastic ...
André Koch (8770430) +3 more
core +1 more source
Cancers, 2021 Simple Summary Cancer rates have been accelerating significantly in recent years. Despite notable advances having been made in cancer therapy, and numerous studies being currently conducted in clinical trials, research is always looking for new treatment.
A. Chianese +7 more
semanticscholar +1 more source
Remodeling of Tumor Immune Microenvironment by Oncolytic Viruses
Frontiers in Oncology, 2021 Oncolytic viruses (OVs) are potential antitumor agents with unique therapeutic mechanisms. They possess the ability of direct oncolysis and the induction of antitumor immunity.
Bin Zhang, Xilei Wang, P. Cheng
semanticscholar +1 more source
Oncolytic viruses in malignant pleural mesothelioma [PDF]
, 2022 Mesothelioma is an aggressive cancer of the serosal membranes with a median survival of 9 to 12 months. Oncolytic viruses are a next-generation therapy. The viruses directly lyse cancer cells and prime the immune system.
Ladhar, Pamelbir
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Oncolytic Viruses for Cancer Therapy: Overcoming the Obstacles [PDF]
, 2010 Targeted therapy of cancer using oncolytic viruses has generated much interest over the past few years in the light of the limited efficacy and side effects of standard cancer therapeutics for advanced disease.
Wang, YH +5 more
core +1 more source