Results 21 to 30 of about 1,862,769 (263)
Recent Clinical Experience With Oncolytic Viruses. [PDF]
Current Pharmaceutical Biotechnology, 2020 There has been interest in using viruses to treat cancer for over a century. Recent clinical efforts, driven on by significant preclinical advances, have focussed on the safety of using replication-competent viruses. Recently published clinical trials of
Prestwich, R +6 more
core +5 more sources
Oncolytic Viruses in Bladder Cancer: Old Idea to Modern Approach [PDF]
Translational Research in Urology, 2022 Some viruses can infect and kill cancer cells. These viruses are known as oncolytic viruses (Virotherapy). The idea of killing cancer cells by oncolytic viruses mainly back to the old idea in the 19th (nineteenth) century. Scientists observed cancer cure
Kayhan Azadmanesh +2 more
doaj +1 more source
Oncolytic Virotherapy for Cancer: Clinical Experience
Biomedicines, 2021 Oncolytic viruses are a new class of therapeutics which are largely in the experimental stage, with just one virus approved by the FDA thus far. While the concept of oncolytic virotherapy is not new, advancements in the fields of molecular biology and ...
Shyambabu Chaurasiya +2 more
doaj +1 more source
Advances in oncolytic herpes simplex virus and adenovirus therapy for recurrent glioma
Frontiers in Immunology, 2023 Recurrent glioma treatment is challenging due to molecular heterogeneity and treatment resistance commonly observed in these tumors. Researchers are actively pursuing new therapeutic strategies.
Mingming Hu +7 more
doaj +1 more source
Recent Developments in Glioblastoma Therapy: Oncolytic Viruses and Emerging Future Strategies
Viruses, 2023 Glioblastoma is the most aggressive form of malignant brain tumor. Standard treatment protocols and traditional immunotherapy are poorly effective as they do not significantly increase the long-term survival of glioblastoma patients.
Azza hamad +4 more
semanticscholar +1 more source
Engineering strategies to enhance oncolytic viruses in cancer immunotherapy
Signal Transduction and Targeted Therapy, 2022 Oncolytic viruses (OVs) are emerging as potentially useful platforms in treatment methods for patients with tumors. They preferentially target and kill tumor cells, leaving healthy cells unharmed.
Yaomei Tian, Daoyuan Xie, Li Yang
semanticscholar +1 more source
Oncolytic Virus Immunotherapy [PDF]
, 2022 Dear Readers, Oncolytic Viruses (OV) are self-propagating agents that can selectively induce the lysis of cancer cells while sparing normal tissues. OV-mediated cancer cell death is often immunogenic and triggers robust anticancer immune responses and ...
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2023 Recent reports have revealed that oncolytic viruses (OVs) play a significant role in cancer therapy. The infection of OVs such as oncolytic vaccinia virus (OVV), vesicular stomatitis virus (VSV), parvovirus, mammalian reovirus (MRV), human adenovirus ...
Yi-Ying Wu +4 more
semanticscholar +1 more source
Development and application of oncolytic viruses as the nemesis of tumor cells
Frontiers in Microbiology, 2023 Viruses and tumors are two pathologies that negatively impact human health, but what occurs when a virus encounters a tumor? A global consensus among cancer patients suggests that surgical resection, chemotherapy, radiotherapy, and other methods are the ...
Xiao Zhu +6 more
semanticscholar +1 more source