Results 121 to 130 of about 76,182 (200)

Regulation of Adenine Nucleotide Metabolism by Adenylate Kinase Isozymes: Physiological Roles and Diseases. [PDF]

Int J Mol Sci, 2023
Fujisawa K.
europepmc   +1 more source

Comparative proteomics analysis of root and nodule mitochondria of soybean

Plant, Cell &Environment, EarlyView.
Abstract Legumes perform symbiotic nitrogen fixation through rhizobial bacteroids housed in specialised root nodules. The biochemical process is energy‐intensive and consumes a huge carbon source to generate sufficient reducing power. To maintain the symbiosis, malate is supplied by legume nodules to bacteroids as their major carbon and energy source ...
Wai‐Ching Sin, Jinhong Liu, Jia Yi Zhong, Hon‐Ming Lam, Boon Leong Lim   +4 more
wiley   +1 more source

Allosteric communication between ligand binding domains modulates substrate inhibition in adenylate kinase. [PDF]

Proc Natl Acad Sci U S A, 2023
Scheerer D, Adkar BV, Bhattacharyya S, Levy D, Iljina M, Riven I, Dym O, Haran G, Shakhnovich EI.   +8 more
europepmc   +1 more source

Brown and beige adipose tissue‐derived metabokine and lipokine inter‐organ signalling in health and disease

Experimental Physiology, EarlyView.
Abstract Adipose tissue has an established endocrine function through the secretion of adipokines. However, a role for bioactive metabolites and lipids, termed metabokines and lipokines, is emerging in adipose tissue‐mediated autocrine, paracrine and endocrine signalling and inter‐organ communication. Traditionally seen as passive entities, metabolites
Anna Malicka, Aysha Ali, Amanda D. V. MacCannell, Lee D. Roberts   +3 more
wiley   +1 more source

The Effect of Heterozygous Mutation of Adenylate Kinase 2 Gene on Neutrophil Differentiation. [PDF]

Int J Mol Sci, 2022
Horiguchi T, Tanimura A, Miyoshi K, Hagita H, Minami H, Noma T.   +5 more
europepmc   +1 more source

Role of cytochrome c heme lyase in the import of cytochrome c into mitochondria [PDF]

, 1988
The import of cytochrome c into Neurospora crassa mitochondria was examined at distinct stages in vitro. The precursor protein, apocytochrome c, binds to mitochondria with high affinity and specificity but is not transported completely across the outer ...
Hergersberg, Christoph, Neupert, Walter, Nicholson, Donald W.   +2 more
core  

The mood stabilizers lithium and valproate disrupt hepatic and intestinal farnesoid X receptor signalling and increase bile synthesis in the rat

Experimental Physiology, EarlyView.
Abstract The mood stabilizers lithium and valproate are psychotropic medications widely used in clinical practice. Despite their proven benefits, many individuals stop their treatment due to the adverse effects. Chronic diarrhoea is a common reason for discontinuation of these drugs; however, the underlying mechanisms are unknown.
Sofia Cussotto, Anna V. Golubeva, Alvaro Lopez Gallardo, Thomaz F. S. Bastiaanssen, Alexander V. Zhdanov, Gerard M. Moloney, Caitriona Scaife, Jane A. English, Susan A. Joyce, Timothy G. Dinan, John F. Cryan   +10 more
wiley   +1 more source

Role of Repeated Conformational Transitions in Substrate Binding of Adenylate Kinase. [PDF]

J Phys Chem B, 2022
Lu J, Scheerer D, Haran G, Li W, Wang W.
europepmc   +1 more source

Evolutionary fates within a microbial population highlight an essential role for protein folding during natural selection

Molecular Systems Biology, 2010
Systems biology can offer a great deal of insight into evolution by quantitatively linking complex properties such as protein structure, folding, and function to the fitness of an organism.
Matthew I Peña, Milya Davlieva, Matthew R Bennett, John S Olson, Yousif Shamoo   +4 more
doaj   +1 more source

A simulation study on the role of mitochondria‐sarcoplasmic reticulum Ca2+ interaction in cardiomyocyte energetics during exercise

The Journal of Physiology, EarlyView.
Abstract figure legend An integrated model of human ventricular myocyte with excitation‐contraction‐energetics coupling was created to systematically analyse the contribution of Ca2+ regulation of mitochondrial enzymes to cardiomyocyte functions during workload transition; i.e. exercise.
Ayako Takeuchi, Satoshi Matsuoka
wiley   +1 more source