Results 131 to 140 of about 86,186 (304)

Functional divergence of protein kinase A regulatory subunit Iβ variants: the importance of N3A motifs in PKA regulation

The FEBS Journal, EarlyView.
The regulatory subunit RIβ of protein kinase A occurs in two variants that differ at residue 268 (A268 versus R268). This seemingly small substitution significantly changes cAMP sensitivity, basal kinase activity, and the dynamic behavior of the regulatory domains.
Maximilian Wallbott, Jui‐Hung Weng, Valeria Pane, Yuliang Ma, Jian Wu, Susan S. Taylor, Friedrich W. Herberg   +6 more
wiley   +1 more source

Preparation of Isotope-labeled Dihydroneopterin 3'-Triphosphate with High Specific Activity

Pteridines, 1990
Isotope-labeled dihydroneopterin 3'-triphosphate with 3H at positions C-1' and C-2', respectively, has been prepared from isotope-labeled glucose as starting material. Glucose was first converted enzymatically to ribose 5-phosphate.
Katzenmeier Gerd, Schwarzkopf Bruno, Van Quang Le, Schmid Cornelia, Bacher Adelbert   +4 more
doaj   +1 more source

Adenylate kinase 9 is essential for sperm function and male fertility in mammals. [PDF]

Proc Natl Acad Sci U S A, 2023
O'Callaghan E, Navarrete-Lopez P, Štiavnická M, Sánchez JM, Maroto M, Pericuesta E, Fernández-González R, O'Meara C, Eivers B, Kelleher MM, Evans RD, Mapel XM, Lloret-Villas A, Pausch H, Balastegui-Alarcón M, Avilés M, Sanchez-Rodriguez A, Roldan ERS, McDonald M, Kenny DA, Fair S, Gutiérrez-Adán A, Lonergan P.   +22 more
europepmc   +1 more source

Evolutionary fates within a microbial population highlight an essential role for protein folding during natural selection

Molecular Systems Biology, 2010
Systems biology can offer a great deal of insight into evolution by quantitatively linking complex properties such as protein structure, folding, and function to the fitness of an organism.
Matthew I Peña, Milya Davlieva, Matthew R Bennett, John S Olson, Yousif Shamoo   +4 more
doaj   +1 more source

Towards a mechanism of AMP‐substrate inhibition in adenylate kinase from Escherichia coli [PDF]

, 1996
Michael A. Sinev, Elena V. Sineva, Varda Ittah, Elisha Haas   +3 more
openalex   +1 more source

Discrete and cell‐specific hypoxic responses in Arabidopsis roots resolved by single‐nuclei transcriptomics

New Phytologist, EarlyView.
Summary With the intensification of unpredictable flooding events because of global warming, there is a need to understand how root cells perceive and respond to oxygen deprivation. The use of high‐throughput single‐nuclei RNA‐sequencing (snRNA‐Seq) allows the examination of gene expression profiles in discrete cell types.
Robert D. Hill, Sean M. Robertson, Abir U. Igamberdiev, Mohammed M. Mira, Olivia Wilkins, Claudio Stasolla   +5 more
wiley   +1 more source

MITOGEN‐ACTIVATED PROTEIN KINASE9 fine‐tunes hypoxia signaling by phosphorylating ERF‐VII transcription factors in Arabidopsis

New Phytologist, EarlyView.
Summary In plants, hypoxia sensing is controlled by the stabilization of group VII ethylene response factors (ERF‐VIIs), which are post‐translationally activated by the mitogen‐activated protein kinases (MAPKs) MPK3 and MPK6. However, how plants fine‐tune the MPK3/MPK6‐mediated phosphorylation of ERF‐VIIs to maintain cellular homeostasis remains ...
De‐Mian Zhou, Ying Zhou, Xu‐Chen Wu, Qing‐Ying Ke, Tian‐Yi Zhang, Zi‐Yuan Yin, Li‐Li Shi, Ke Liao, Shi Xiao, Qin‐Fang Chen   +9 more
wiley   +1 more source

Anti-adenylate kinase 5 encephalitis: Clinical characteristics, diagnosis, and management of this rare entity. [PDF]

J Transl Autoimmun, 2023
Li EC, Lai QL, Cai MT, Fang GL, Shen CH, Ding MP, Zhang YX.   +6 more
europepmc   +1 more source

Adenylate cyclase 1 (ADCY1; AC1); protein kinase Mζ (PKMζ) [PDF]

, 2010

openalex   +1 more source

Contribution of Sympathetic Sensory Coupling to Craniofacial Nociception

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Stress and anxiety are associated with increased pain intensity in temporomandibular disorders (TMDs) patients. It is possible that this association is due to a direct interaction between the sympathetic and sensory nervous systems. This narrative review examines evidence for a potential sympathetic sensory interaction in deep craniofacial ...
Brian Edwin Cairns
wiley   +1 more source