Results 11 to 20 of about 86,186 (304)
Adenylate kinase AK2 isoform integral in embryo and adult heart homeostasis. [PDF]
Biochem Biophys Res Commun, 2021 Zhang S +6 more
europepmc +2 more sources
Prognostic and therapeutic potential of Adenylate kinase 2 in lung adenocarcinoma. [PDF]
Sci Rep, 2019 Liu H +7 more
europepmc +3 more sources
β-Cyclodextrins alter the energy metabolism-related enzyme activities in rats [PDF]
Anais da Academia Brasileira de Ciências, 2023 Although widely used in medicine, separation technology, and other fields, the effects of cyclodextrins on the activities of phosphoryl transfer enzymes have not been previously evaluated. In vivo studies evaluated the function of cyclodextrins as active
FRANCINE R. IANISKI +15 more
doaj +1 more source
Correlated inter-domain motions in adenylate kinase. [PDF]
PLoS Computational Biology, 2014 Correlated inter-domain motions in proteins can mediate fundamental biochemical processes such as signal transduction and allostery. Here we characterize at structural level the inter-domain coupling in a multidomain enzyme, Adenylate Kinase (AK), using ...
Santiago Esteban-Martín +7 more
doaj +1 more source
Conformational dynamics of a ligand-free adenylate kinase. [PDF]
PLoS ONE, 2013 Adenylate kinase (AdK) is a phosphoryl-transfer enzyme with important physiological functions. Based on a ligand-free open structure and a ligand-bound closed structure solved by crystallography, here we use molecular dynamics simulations to examine the ...
Hyun Deok Song, Fangqiang Zhu
doaj +1 more source
Cell Reports, 2023 Summary: Male mice lacking the androgen receptor (AR) in pancreatic β cells exhibit blunted glucose-stimulated insulin secretion (GSIS), leading to hyperglycemia.
Weiwei Xu +34 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2020 In our search for novel biocatalysts for the synthesis of nucleic acid derivatives, we found a good candidate in a putative dual-domain hypoxanthine-guanine phosphoribosyltransferase (HGPRT)/adenylate kinase (AMPK) from Zobellia galactanivorans (ZgHGPRT ...
Javier Acosta +9 more
doaj +1 more source
On the Significance of the ADNT1 Carrier in Arabidopsis thaliana under Waterlogging Conditions
Biomolecules, 2023 Among the adenylate carriers identified in Arabidopsis thaliana, only the AMP/ATP transporter ADNT1 shows increased expression in roots under waterlogging stress conditions. Here, we investigated the impact of a reduced expression of ADNT1 in A. thaliana
Roberto Neri-Silva +10 more
doaj +1 more source
Adenylate Kinase of Porcine Heart [PDF]
European Journal of Biochemistry, 1974 The activity of adenylate kinase (ATP : AMP-phosphotransferase, EC 2.7.4.3) in porcine heart is about one-sixth that in porcine skeletal muscle on a wet weight basis. Essentially all of the activity of the heart preparations, 70–80 units/g tissue, was present in the soluble fraction.
S, Kubo, L H, Noda
openaire +2 more sources
The inhibition of adenylate kinase by 2,4-thiazolidinedione evaluated by protein-ligand docking
ADMET and DMPK, 2017 Due to its crucial role in nucleotide metabolism, adenylate kinase deserves a special attention in screening of potential inhibitors. Herein, we report the assessment of the relative orientation of the ligand 2,4-thiazolidinedione to adenylate kinase ...
Mihaela Ileana Ionescu
doaj +1 more source