Host-Induced Gene Silencing of an Adenylate Kinase Gene Involved in Fungal Energy Metabolism Improves Plant Resistance to Verticillium dahliae [PDF]
Biomolecules, 2020 Verticillium wilt, caused by the ascomycete fungus Verticillium dahliae (Vd), is a devastating disease of numerous plant species. However, the pathogenicity/virulence-related genes in this fungus, which may be potential targets for improving plant ...
Xiaofeng Su +8 more
doaj +2 more sources
Adenylate Kinase 4 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an m6A-Based Epitranscriptomic Mechanism. [PDF]
Mol Ther, 2020 Liu X +9 more
europepmc +2 more sources
β-Cyclodextrins alter the energy metabolism-related enzyme activities in rats [PDF]
Anais da Academia Brasileira de Ciências, 2023 Although widely used in medicine, separation technology, and other fields, the effects of cyclodextrins on the activities of phosphoryl transfer enzymes have not been previously evaluated. In vivo studies evaluated the function of cyclodextrins as active
FRANCINE R. IANISKI +15 more
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Adenylate Kinase of Porcine Heart [PDF]
European Journal of Biochemistry, 1974 The activity of adenylate kinase (ATP : AMP-phosphotransferase, EC 2.7.4.3) in porcine heart is about one-sixth that in porcine skeletal muscle on a wet weight basis. Essentially all of the activity of the heart preparations, 70–80 units/g tissue, was present in the soluble fraction.
Lafayette H. Noda, Shuichiro Kubo
openaire +3 more sources
Molecular mechanism of ATP versus GTP selectivity of adenylate kinase. [PDF]
Proc Natl Acad Sci U S A, 2018 Rogne P +5 more
europepmc +2 more sources
On the Significance of the ADNT1 Carrier in Arabidopsis thaliana under Waterlogging Conditions
Biomolecules, 2023 Among the adenylate carriers identified in Arabidopsis thaliana, only the AMP/ATP transporter ADNT1 shows increased expression in roots under waterlogging stress conditions. Here, we investigated the impact of a reduced expression of ADNT1 in A. thaliana
Roberto Neri-Silva +10 more
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The inhibition of adenylate kinase by 2,4-thiazolidinedione evaluated by protein-ligand docking
ADMET and DMPK, 2017 Due to its crucial role in nucleotide metabolism, adenylate kinase deserves a special attention in screening of potential inhibitors. Herein, we report the assessment of the relative orientation of the ligand 2,4-thiazolidinedione to adenylate kinase ...
Mihaela Ileana Ionescu
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Substrate Induced Structural and Dynamics Changes in Human Phosphomevalonate Iinase and Implications for Mechanism [PDF]
, 2009 Phosphomevalonate kinase (PMK) catalyzes an essential step in the mevalonate pathway, which is the only pathway for synthesis of isoprenoids and steroids in humans.
Cai, Sheng +7 more
core +2 more sources
The flagellar adenylate kinases of Trypanosoma cruzi [PDF]
FEMS Microbiology Letters, 2015 Adenylate kinases (ADK) are key enzymes involved in cell energy management. Trypanosomatids present the highest number of variants in a single cell in comparison with the rest of the living organisms. In this work, we characterized two flagellar ADKs from Trypanosoma cruzi, called TcADK1 and TcADK4, which are also located in the cell cytosol ...
Camara, María de los Milagros +3 more
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The crystal structure of human adenylate kinase 6: An adenylate kinase localized to the cell nucleus [PDF]
Proceedings of the National Academy of Sciences, 2005 Adenylate kinases (AKs) play important roles in nucleotide metabolism in all organisms and in cellular energetics by means of phosphotransfer networks in eukaryotes. The crystal structure of a human AK named AK6 was determined by in-house sulfur single-wavelength anomalous dispersion phasing methods and refined to 2.0-Å resolution with a ...
Yu-He Liang +11 more
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