Results 31 to 40 of about 945,743 (288)

Potential and limitations of PKA/ PKG inhibitors for platelet studies

open access: yesPlatelets, 2022
Cyclic nucleotides (cAMP and cGMP) and corresponding protein kinases, protein kinase A (PKA) and protein kinase G (PKG), are the main intracellular mediators of endothelium-derived platelet inhibitors. Pharmacological PKA/PKG inhibitors are often used to
Valentina Shpakova   +3 more
doaj   +1 more source

Pyrophosphate-Dependent ATP Formation from Acetyl Coenzyme A in Syntrophus aciditrophicus, a New Twist on ATP Formation. [PDF]

open access: yes, 2016
UnlabelledSyntrophus aciditrophicus is a model syntrophic bacterium that degrades key intermediates in anaerobic decomposition, such as benzoate, cyclohexane-1-carboxylate, and certain fatty acids, to acetate when grown with hydrogen-/formate-consuming ...
Erde, Jonathan   +17 more
core   +2 more sources

ADENYLATE KINASE AND MALIGNANT HYPERPYREXIA

open access: yesBritish Journal of Anaesthesia, 1982
The isoenzyme pattern and activity of adenylate kinase was studied in muscle and red blood cells from individuals and swine shown to be susceptible to malignant hyperpyraria. No abnormality in adenylate kinase isoenzyme pattern or activity was found.
L.A. Marjanen, Michael A. Denborough
openaire   +3 more sources

Oral cancer cells may rewire alternative metabolic pathways to survive from siRNA silencing of metabolic enzymes. [PDF]

open access: yes, 2014
BackgroundCancer cells may undergo metabolic adaptations that support their growth as well as drug resistance properties. The purpose of this study is to test if oral cancer cells can overcome the metabolic defects introduced by using small interfering ...
Brumbaugh, Jeffrey   +8 more
core   +1 more source

Adenylate kinase-independent thiamine triphosphate accumulation under severe energy stress in Escherichia coli

open access: yesBMC Microbiology, 2008
Background Thiamine triphosphate (ThTP) exists in most organisms and might play a role in cellular stress responses. In E. coli, ThTP is accumulated in response to amino acid starvation but the mechanism of its synthesis is still a matter of controversy.
Wins Pierre   +4 more
doaj   +1 more source

Metabolomic analysis of human oral cancer cells with adenylate kinase 2 or phosphorylate glycerol kinase 1 inhibition. [PDF]

open access: yes, 2017
The purpose of this study was to use liquid chromatography-mass spectrometry (LC-MS) with XCMS for a quantitative metabolomic analysis of UM1 and UM2 oral cancer cells after knockdown of metabolic enzyme adenylate kinase 2 (AK2) or phosphorylate glycerol
Cheng, Siliangyu   +6 more
core   +1 more source

Inhibition of Food Intake by PACAP in the Hypothalamic Ventromedial Nuclei is Mediated by NMDA Receptors [PDF]

open access: yes, 2014
Central injections of pituitary adenylate cyclase-activating polypeptide (PACAP) into the ventromedial nuclei (VMN) of the hypothalamus produce hypophagia that is dependent upon the PAC1 receptor; however, the signaling downstream of this receptor in the
Choi, Sujean   +3 more
core   +2 more sources

Adenylate effects on protein phosphorylation in the interenvelope lumen of pea chloroplasts [PDF]

open access: yes, 1989
A 64-kilodalton (kDa) protein, situated in the lumen between the inner and outer envelopes of pea (Pisum sativum L.) chloroplasts (Soll and Bennett 1988, Eur. J.
A.M. Edelman   +23 more
core   +1 more source

Structural relationships in the adenylate kinase family [PDF]

open access: yesEuropean Journal of Biochemistry, 1986
The sequences of five distantly related adenylate kinases have been aligned. The local conservation of amino acids is discussed in the light of the known three‐dimensional structure of one of the enzymes, the cytosolic isoenzyme 1 (AK1) from porcine muscle. The similarity profile outlines clearly the active site in the cleft of the spatial structure of
Schulz, G.   +6 more
openaire   +4 more sources

Cofactor engineering improved CALB production in Pichia pastoris through heterologous expression of NADH oxidase and adenylate kinase. [PDF]

open access: yesPLoS ONE, 2017
The cofactor engineering strategy can relieve the metabolic stress induced by expression of recombinant protein in cellular metabolism related to cofactor and energy reactions.
Charumathi Jayachandran   +2 more
doaj   +1 more source

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