Results 41 to 50 of about 86,186 (304)

Mimics and Diagnostic Pitfalls of Anti-Adenylate Kinase 5 Limbic Encephalitis. [PDF]

CNS Neurosci Ther
Mimics of anti‐AK5 encephalitis are common and that misdiagnosis is often driven by non‐specific symptoms and clinically irrelevant antibody results. The absence of cognitive impairment as a major symptom, prominence of psychiatric and behavioral symptoms, isolated from serum positivity or low CSF antibody titers (< 1:100), and objective clinical ...
Wang J, Yi T, Wang G, Wang M, Zhou D, Li J.   +5 more
europepmc   +2 more sources

Functional modes of proteins are among the most robust ones [PDF]

, 2004
It is shown that a small subset of modes which are likely to be involved in protein functional motions of large amplitude can be determined by retaining the most robust normal modes obtained using different protein models.
A. Atilgan, B. R. Brooks, C. Chennubhotla, G. Li, K. Hinsen, M. Tirion, S. Nicolay, Y. Wu, Y.-H. Sanejouand   +8 more
core   +3 more sources

ADENYLATE KINASE AND MALIGNANT HYPERPYREXIA

British Journal of Anaesthesia, 1982
The isoenzyme pattern and activity of adenylate kinase was studied in muscle and red blood cells from individuals and swine shown to be susceptible to malignant hyperpyraria. No abnormality in adenylate kinase isoenzyme pattern or activity was found.
L A, Marjanen, M A, Denborough
openaire   +2 more sources

Refolding of urea-denatured adenylate kinase [PDF]

Biochemical Journal, 1998
The refolding of urea-denatured adenylate kinase (EC 2.7.4.3) has been followed by formation of the secondary structure, change of surface hydrophobicity and recovery of catalytic activity. During refolding of adenylate kinase with a 20–80-fold dilution of 4 M urea-denatured enzyme at 10 °C, the formation of the secondary structure is a fast process ...
H j, Zhang, X R, Sheng, X M, Pan, J M, Zhou   +3 more
openaire   +2 more sources

Stable Isotope Tracing Uncovers Reduced γ/β-ATP Turnover and Metabolic Flux Through Mitochondrial-Linked Phosphotransfer Circuits in Aggressive Breast Cancer Cells

Frontiers in Oncology, 2022
Changes in dynamics of ATP γ- and β-phosphoryl turnover and metabolic flux through phosphotransfer pathways in cancer cells are still unknown. Using 18O phosphometabolite tagging technology, we have discovered phosphotransfer dynamics in three breast ...
Aleksandr Klepinin, Aleksandr Klepinin, Sten Miller, Sten Miller, Indrek Reile, Marju Puurand, Egle Rebane-Klemm, Egle Rebane-Klemm, Ljudmila Klepinina, Ljudmila Klepinina, Heiki Vija, Song Zhang, Andre Terzic, Andre Terzic, Petras Dzeja, Tuuli Kaambre   +15 more
doaj   +1 more source

Reversal of age-related learning deficiency by the vertebrate PACAP and IGF-1 in a novel invertebrate model of aging: the pond snail (Lymnaea Stagnalis) [PDF]

, 2014
With the increase of life span, nonpathological age-related memory decline is affecting an increasing number of people. However, there is evidence that age-associated memory impairment only suspends, rather than irreversibly extinguishes, the intrinsic ...
Alexander, Audesirk, Chaudhury, D. Regl di, Delcourt, Du, G. Kemenes, Hattiangady, Hermann, Hernadi, I. Kemenes, J  zsa, Kemenes, Kemenes, Lee, Markowska, Otto, Otto, Patel, Patel, Pavlopoulos, Pirger, Pirger, Pirger, Roberto, S. Naskar, Sacchetti, Shioda, Silhol, Tamas, Telegdy, Vaudry, Watson, Watson, Yang, Yeoman, Z. Laszlo, Z. Pirger, Zhang   +38 more
core   +2 more sources

Growth Hormone (GH)-Releasing Peptide Stimulation of GH Release from Human Somatotroph Adenoma Cells: Interaction with GH-Releasing Hormone, Thyrotropin- Releasing Hormone, and Octreotide. [PDF]

, 1994
The synthetic hexapeptide GH-releasing peptide (GHRP; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) specifically stimulates GH secretion in humans in vivo and in animals in vitro and in vivo via a still unknown receptor and mechanism.
Brockmeier, S., Lange, M., Müller, Otto-Albrecht, Renner, U., Schopohl, Jochen, Stalla, G. K., Strasburger, Christian J., Werder, K. von   +7 more
core   +1 more source

Adenylate Kinase Activity in Mycobacterium leprae [PDF]

Microbiology, 1986
Adenylate kinase (ATP:AMP phosphotransferase, EC 2.7.4.3) was detected in partially purified preparations of cell-free extracts of Mycobacterium leprae. The apparent Km values of M. leprae adenylate kinase for ADP and Mg2+ were 1 X 10(-4) M, respectively.
Y N, Lee, M J, Colston
openaire   +2 more sources

Coupled ATPase-adenylate kinase activity in ABC transporters

Nature Communications, 2016
ATP-binding cassette (ABC) transporters hydrolyse ATP to transport molecules across the cell membrane. Here Vogelet al. show that the ABC exporter MsBA can couple ATP hydrolyse to an adenylate kinase activity that seems to be predominant at low ATP ...
Hundeep Kaur, Andrea Lakatos-Karoly, Ramona Vogel, Anne Nöll, Robert Tampé, Clemens Glaubitz   +5 more
doaj   +1 more source

Rare hereditary nonspherocytic hemolytic anemia caused by a novel homozygous mutation, c.301C > A, (Q101K), in the AK1 gene in an Indian family

BMC Medical Genomics, 2021
Background Adenylate kinase (AK) deficiency is a rare red cell enzymopathy associated with moderate to severe congenital nonspherocytic hemolytic anemia, along with mental and psychomotor retardation (in exceptional cases).
Rashmi Dongerdiye, Abhilasha Sampagar, Rati Devendra, Prashant Warang, Prabhakar Kedar   +4 more
doaj   +1 more source