Results 51 to 60 of about 86,186 (304)
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Objectives Acute cerebral ischemia is characterized by several pathological processes evolving during time, which contribute to the final tissue damage. Secondary processes, such as prolonged inflammatory response, impaired mitochondrial function and oxidative stress, are responsible for the progression of brain injury to the peri‐infarct area,
Fioravante Capone +8 more
wiley +1 more source
Subnanometre enzyme mechanics probed by single-molecule force spectroscopy
Nature Communications, 2016 Adenylate kinase catalyses the interconversion of adenosine phosphates, and plays a crucial role in maintaining cellular energy homeostasis. Here, the authors use single molecule optical tweezers to understand how the enzyme’s conformation dynamics ...
Benjamin Pelz +4 more
doaj +1 more source
Rapid Detection of Enterohaemorrhagic E.coli Using Phage-Based Bioluminescent Assay [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: There is a need for a reliable, time-saving, and specific detection assay for coliforms, environmental E. coli, and Enterobacteriaceae worldwide. Aim: To innovate a new principle of phage-based rapid diagnostic test for detecting E.
Sabah AA Jassim +3 more
doaj +1 more source
Natriuretic peptide receptors regulate cytoprotective effects in a human ex vivo 3D/bioreactor model [PDF]
, 2013 © 2013 Peake et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Achan, P +8 more
core +3 more sources
Identification and Expression Analysis of Adenylate Kinase Gene Family in Potato
Horticulturae, 2023 Adenylate kinase (ADK) is a key enzyme that is widely distributed in animals and plants. It plays an important role in growth and stress response. However, ADK genes in potato (StADK) have been little reported. It is of great significance to identify ADK
Xiang Li +6 more
doaj +1 more source
The T2238C human atrial natriuretic peptide molecular variant and the risk of cardiovascular diseases [PDF]
, 2018 Atrial natriuretic peptide (ANP) is a cardiac hormone which plays important functions to maintain cardio-renal homeostasis. The peptide structure is highly conserved among species. However, a few gene variants are known to fall within the human ANP gene.
Bianchi, Franca +5 more
core +2 more sources
Molecular and functional characterization of a Trypanosoma cruzi nuclear adenylate kinase isoform. [PDF]
PLoS Neglected Tropical Diseases, 2013 Trypanosoma cruzi, the etiological agent of Chagas' disease, is an early divergent eukaryote in which control of gene expression relies mainly in post-transcriptional mechanisms.
María de los Milagros Cámara +4 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Frontiers in Molecular Neuroscience, 2018 We have previously demonstrated that activation of serotonin 5-HT7 receptors (5-HT7R) reverses metabotropic glutamate receptor-mediated long term depression (mGluR-LTD) in the hippocampus of wild-type (WT) and Fmr1 Knockout (KO) mice, a model of Fragile ...
Lara Costa +12 more
doaj +1 more source
High and stable ATP levels prevent aberrant intracellular protein aggregation in yeast
eLife, 2022 Adenosine triphosphate (ATP) at millimolar levels has recently been implicated in the solubilization of cellular proteins. However, the significance of this high ATP level under physiological conditions and the mechanisms that maintain ATP remain unclear.
Masak Takaine +2 more
doaj +1 more source