Results 61 to 70 of about 945,743 (288)

A guanosine 5′-triphosphate-dependent protein kinase is localized in the outer envelope membrane of pea chloroplasts [PDF]

, 1988
A guanosine 5-triphosphate (GTP)-dependent protein kinase was detected in preparations of outer chloroplast envelope membranes of pea (Pisum sativum L.) chloroplasts.
A.M. Edelman, A.R. Ashton, C. foyer, C. Schindler, C.V.C. Glover, D.J. Arnon, F.A. Ventimiglia, G.E. Lienhard, G.M. Hathaway, G.M. Hathaway, G.M. Hathaway, H. Erdmann, H. Hidaka, J. Joyard, J. Soll, J. Soll, J. Soll, J. Soll, J.F. Allen, J.F. Kuo, J.G. Chafouleas, K. Birkenhead, K. Cline, K. Keegstra, P. Bhalla, R. Ranjeva, R.A. Douce, R.J.H. Budde, S. Gowda, S. Murakami, S.J. Coughlan, T.F.J. Yan, U.K. Laemmli, W.A. Laing, Z.F. Lin   +34 more
core   +1 more source

Adenylate Kinase Activity in Mycobacterium leprae [PDF]

Microbiology, 1986
Adenylate kinase (ATP:AMP phosphotransferase, EC 2.7.4.3) was detected in partially purified preparations of cell-free extracts of Mycobacterium leprae. The apparent Km values of M. leprae adenylate kinase for ADP and Mg2+ were 1 X 10(-4) M, respectively.
Young Nam Lee, M. J. Colston
openaire   +3 more sources

Subnanometre enzyme mechanics probed by single-molecule force spectroscopy

Nature Communications, 2016
Adenylate kinase catalyses the interconversion of adenosine phosphates, and plays a crucial role in maintaining cellular energy homeostasis. Here, the authors use single molecule optical tweezers to understand how the enzyme’s conformation dynamics ...
Benjamin Pelz, Gabriel Žoldák, Fabian Zeller, Martin Zacharias, Matthias Rief   +4 more
doaj   +1 more source

The energy landscape of adenylate kinase during catalysis

Nature Structural &Molecular Biology, 2014
Kinases perform phosphoryl-transfer reactions in milliseconds; without enzymes, these reactions would take about 8,000 years under physiological conditions.
S. J. Kerns, R. Agafonov, Young-jin Cho, Francesco Pontiggia, R. Otten, Dimitar V. Pachov, S. Kutter, Lien A Phung, P. N. Murphy, V. Thai, T. Alber, Michael F. Hagan, D. Kern   +12 more
semanticscholar   +1 more source

The ever unfolding story of cAMP signaling in trypanosomatids: vive la difference! [PDF]

, 2015
Kinetoplastids are unicellular, eukaryotic, flagellated protozoans containing the eponymous kinetoplast. Within this order, the family of trypanosomatids are responsible for some of the most serious human diseases, including Chagas disease (Trypanosoma ...
De Koning, Harry P., Kalejaiye, Titilola D., Tagoe, Daniel N. A.   +2 more
core   +1 more source

Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells

Cell Reports, 2023
Summary: Male mice lacking the androgen receptor (AR) in pancreatic β cells exhibit blunted glucose-stimulated insulin secretion (GSIS), leading to hyperglycemia.
Weiwei Xu, M.M. Fahd Qadir, Daniela Nasteska, Paula Mota de Sa, Caroline M. Gorvin, Manuel Blandino-Rosano, Charles R. Evans, Thuong Ho, Evgeniy Potapenko, Rajakrishnan Veluthakal, Fiona B. Ashford, Stavroula Bitsi, Jia Fan, Manika Bhondeley, Kejing Song, Venkata N. Sure, Siva S.V.P. Sakamuri, Lina Schiffer, Wandy Beatty, Rachael Wyatt, Daniel E. Frigo, Xiaowen Liu, Prasad V. Katakam, Wiebke Arlt, Jochen Buck, Lonny R. Levin, Tony Hu, Jay Kolls, Charles F. Burant, Alejandra Tomas, Matthew J. Merrins, Debbie C. Thurmond, Ernesto Bernal-Mizrachi, David J. Hodson, Franck Mauvais-Jarvis   +34 more
doaj  

Activation of Serotonin 5-HT7 Receptors Modulates Hippocampal Synaptic Plasticity by Stimulation of Adenylate Cyclases and Rescues Learning and Behavior in a Mouse Model of Fragile X Syndrome

Frontiers in Molecular Neuroscience, 2018
We have previously demonstrated that activation of serotonin 5-HT7 receptors (5-HT7R) reverses metabotropic glutamate receptor-mediated long term depression (mGluR-LTD) in the hippocampus of wild-type (WT) and Fmr1 Knockout (KO) mice, a model of Fragile ...
Lara Costa, Lara Maria Sardone, Carmela Maria Bonaccorso, Simona D’Antoni, Michela Spatuzza, Walter Gulisano, Maria Rosaria Tropea, Daniela Puzzo, Marcello Leopoldo, Enza Lacivita, Maria Vincenza Catania, Maria Vincenza Catania, Lucia Ciranna   +12 more
doaj   +1 more source

Stable Isotope Tracing Uncovers Reduced γ/β-ATP Turnover and Metabolic Flux Through Mitochondrial-Linked Phosphotransfer Circuits in Aggressive Breast Cancer Cells

Frontiers in Oncology, 2022
Changes in dynamics of ATP γ- and β-phosphoryl turnover and metabolic flux through phosphotransfer pathways in cancer cells are still unknown. Using 18O phosphometabolite tagging technology, we have discovered phosphotransfer dynamics in three breast ...
Aleksandr Klepinin, Aleksandr Klepinin, Sten Miller, Sten Miller, Indrek Reile, Marju Puurand, Egle Rebane-Klemm, Egle Rebane-Klemm, Ljudmila Klepinina, Ljudmila Klepinina, Heiki Vija, Song Zhang, Andre Terzic, Andre Terzic, Petras Dzeja, Tuuli Kaambre   +15 more
doaj   +1 more source

A cAMP-binding ectoprotein in the yeast Saccharomyces cerevisiae [PDF]

, 1991
tides 10, 593 ...
Achstetter T., Baroni M. D., Behrens M. M., Biilow R., Bregman D. B., Brunton L. L., Cannon J. F., Caras I. W., Caras I. W., Carr S. A., Clegg C., Conzelmann A., Conzelmann A., Corbin J. D., Cross G. A. M., Dallner G., Davitz M. A., Davitz M. A., DeCamilli P., Doering T. L., Edelman A. M., Ferguson M. A. J., Ferguson M. A. J., Ferguson R., Fersht A., Flockart D. A., Gruber W., Hixson C. S., Ishihara M., Jaynes P. K., Johnson K. E., Kamps M. P., Kiibler D., Korc-Grodzicki B., Kunisawa R., Lang B., Lohmann S. M., Lohmann S. M., Low M. G., Low M. G., Matsumoto K., Matsumoto K., Matsumoto K., Matsumoto K., Matsumoto K., Merino A., Mitts M. R., Mostov K. E., Muller G., Muller G., Muller G., Muller G„, Nairn A. C., Nigam S. K., Nigg E. A., Nigg E. A., Olson S., Pall G., Rhee T., Rodel G., Sakar D., Salomon Y., Smith M. E., Srere P. A., Stieger A., Takami N., Thorner J., Toda T., Trams E. G., Uno I., Vai M., Wen T. C., Wingender-Drissen R.   +72 more
core   +3 more sources

The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth

Nature Communications, 2014
Adenylate kinase 2 (AK2), which balances adenine nucleotide pool, is a multi-functional protein. Here we show that AK2 negatively regulates tumour cell growth.
Hyunjoo Kim, Ho-June Lee, Yumin Oh, Seon-Guk Choi, Se-hoon Hong, Hyo-Jin Kim, Song-Yi Lee, Ji-Woo Choi, Deog Su Hwang, Key‐Sun Kim, Hyo-Joon Kim, Jianke Zhang, H. Youn, D. Noh, Yong-Keun Jung   +14 more
semanticscholar   +1 more source