Results 81 to 90 of about 86,186 (304)

cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission. [PDF]

open access: yes, 2015
Blocking Plasmodium falciparum transmission to mosquitoes has been designated a strategic objective in the global agenda of malaria elimination. Transmission is ensured by gametocyte-infected erythrocytes (GIE) that sequester in the bone marrow and at ...
A Dawn   +74 more
core   +9 more sources

Differential roles of EA‐TRAPed cells in the anterior cingulate cortex across various intervention times in inflammatory pain

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The cumulative effect of EA analgesia is partially attributed to the activation of EA‐TRAPed cells in ACC. Multiple EA sessions and single EA sessions activated different neuronal populations in the ACC. The enhanced analgesic effect of multiple EA sessions may be attributed to an increase in the proportion of GABAergic neurons within the ACC. Abstract
Zi Guo   +8 more
wiley   +1 more source

Inhibition of Streptococcus pneumoniae adenylate kinase by some 5-arylidene-thiazolidin-4-on-2-thione derivates

open access: yesRomanian Journal of Laboratory Medicine, 2013
Adenilat kinaza este o enzimă ubiquitară prezentă atât la procariote cât şi la eucariote. în această lucrare am testat acţiunea inhibitorie a şase 5-ariliden-tiazolidin-4-on-2-tione faţă de adenilat kinaza din Strepto- coccus pneumoniae (A\Ksp) prin ...
Ionescu Miliaela Ileana   +4 more
doaj   +1 more source

Regulation of polarised growth in fungi [PDF]

open access: yes, 2008
Polarised growth in fungi occurs through the delivery of secretory vesicles along tracks formed by cytoskeletal elements to specific sites on the cell surface where they dock with a multiprotein structure called the exocyst before fusing with the ...
Adamo   +112 more
core   +1 more source

Evolved DNAzymes and Stable Activation Chemistry Enable High‐Efficiency DNA Ligation

open access: yesChemistry – A European Journal, EarlyView.
In vitro selection of pre‐structured DNA libraries and chemical screening of alternative activation groups yielded trans‐acting DNAzymes with faster ligation rates and enhanced DNA substrate stability. The combination of C3S1 DNAzymes and phosphobenzimidazole‐activated DNA substrates provides improved DNA ligation performance, offering promise for ...
Connor Nurmi   +3 more
wiley   +1 more source

Optimization of ATP synthase function in mitochondria and chloroplasts via the adenylate kinase equilibrium

open access: yesFrontiers in Plant Science, 2015
The bulk of ATP synthesis in plants is performed by ATP synthase, the main bioenergetics engine of cells, operating both in mitochondria and in chloroplasts.
Abir U Igamberdiev, Leszek A Kleczkowski
doaj   +1 more source

Multiscale coarse-graining of the protein energy landscape. [PDF]

open access: yesPLoS Computational Biology, 2010
A variety of coarse-grained (CG) models exists for simulation of proteins. An outstanding problem is the construction of a CG model with physically accurate conformational energetics rivaling all-atom force fields.
Ronald D Hills   +2 more
doaj   +1 more source

Augmented Cystine–Glutamate Exchange by Pituitary Adenylate Cyclase-activating Polypeptide Signaling via the VPAC1 Receptor [PDF]

open access: yes, 2014
In the central nervous system, cystine import in exchange for glutamate through system xc- is critical for the production of the antioxidant glutathione by astrocytes, as well as the maintenance of extracellular glutamate. Therefore, regulation of system
Arimura   +74 more
core   +2 more sources

Harnessing Piezoelectric Biomaterials for Pathogenic Eradication and Tissue Regeneration

open access: yesExploration, EarlyView.
This review highlights recent advances in piezoelectric biomaterials for antibacterial therapy and tissue regeneration, discussing material classifications, catalytic mechanisms, property enhancements, biomedical applications, and future challenges in clinical translation.
Wenxuan Mao   +11 more
wiley   +1 more source

The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulation.

open access: yes, 2010
OBJECTIVE: Elevated serum levels of the acute-phase protein serum amyloid A (SAA) are a marker for active rheumatoid arthritis (RA), and SAA can also be found in the tissues of patients with active RA.
Björkman, Lena   +5 more
core   +1 more source

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