Results 11 to 20 of about 53,020 (288)

The diagnostic value of alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) measurement in the sera of patients with brain tumor

open access: yesArchives of Medical Science, 2017
Introduction: Alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) exist in the brain. Alcohol dehydrogenase and ALDH are also present in brain tumor cells.
Wojciech Jelski   +5 more
doaj   +2 more sources

Dose-Dependent Change in Elimination Kinetics of Ethanol due to Shift of Dominant Metabolizing Enzyme from ADH 1 (Class I) to ADH 3 (Class III) in Mouse

open access: yesInternational Journal of Hepatology, 2012
ADH 1 and ADH 3 are major two ADH isozymes in the liver, which participate in systemic alcohol metabolism, mainly distributing in parenchymal and in sinusoidal endothelial cells of the liver, respectively. We investigated how these two ADHs contribute to
Takeshi Haseba   +3 more
doaj   +2 more sources

ADH IB expression, but not ADH III, is decreased in human lung cancer. [PDF]

open access: yesPLoS ONE, 2012
Endogenous S-nitrosothiols, including S-nitrosoglutathione (GSNO), mediate nitric oxide (NO)-based signaling, inflammatory responses, and smooth muscle function.
Sarah C Mutka   +6 more
doaj   +2 more sources

[ADH and cAMP receptor binding in the kidney medulla of mice insensitive to ADH]

open access: yes, 1991
Specific binding of ADH by the membrane fraction of the kidney medulla was lower in the normal CBA mice than in mutant mice with nephrogenic diabetes.
Solenov, E I   +2 more
core   +8 more sources

DataSheet_1_[18F]AlF-NOTA-ADH-1: A new PET molecular radiotracer for imaging of N-cadherin-positive tumors.docx

open access: yes, 2023
BackgroundThe cell adhesion molecule (CAM) N-cadherin has become an important target for tumor therapy. The N-cadherin antagonist, ADH-1, exerts significant antitumor activity against N-cadherin-expressing cancers.MethodsIn this study, [18F]AlF-NOTA-ADH ...
Zhenfeng Liu (431113)   +23 more
core   +1 more source

Robots and Minimal, Physics-Informed Features: A Hybrid Framework for Enzyme Catalysis. [PDF]

open access: yesAdv Sci (Weinh)
Robotic experimentation and physics‐informed machine learning combine to predict enzyme substrate scope. With a handful of interpretable features derived from docking and quantum mechanics calculations, our model rivals descriptor‐heavy AI approaches and extrapolates to unseen substrates and enzyme classes.
Onishchenko N   +8 more
europepmc   +2 more sources

A non-synonymous variant in ADH1B is strongly associated with prenatal alcohol use in a European sample of pregnant women. [PDF]

open access: yes, 2009
Pregnant women are advised to abstain from alcohol despite insufficient evidence on the fetal consequences of moderate prenatal alcohol use. Mendelian randomization could help distinguish causal effects from artifacts due to residual confounding and ...
Sayal, K   +15 more
core   +1 more source

A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium [PDF]

open access: yes, 2011
Genome-wide association studies (GWAS) have been successful in identifying common genetic variation involved in susceptibility to etiologically complex disease.
Marsit CJ   +934 more
core   +2 more sources

Alcohol dehydrogenase (ADH) Influence of homo- and heterologous ADH administration on albino rats craving for alcohol and on ADH isozyme activity in the liver [PDF]

open access: yes, 1992
The effects of homo- and heterologous alcohol dehydrogenase (ADH) administration into albino rats were investigated. It was found that homologous ADH increases and heterologous ADH decreases the craving for ethanol.
Ashmarin, I.P.   +11 more
core   +1 more source

Ultrasensitive and Highly Selective Graphene-Based Field-Effect Transistor Biosensor for Anti-Diuretic Hormone Detection

open access: yesSensors, 2020
Nephrogenic diabetes insipidus (NDI), which can be congenital or acquired, results from the failure of the kidney to respond to the anti-diuretic hormone (ADH). This will lead to excessive water loss from the body in the form of urine.
Reena Sri Selvarajan   +4 more
doaj   +1 more source

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