Results 11 to 20 of about 41,061 (259)
Molecules, 2022 (R)-1-[3,5-bis(trifluoromethyl)phenyl]ethanamine, a key chiral intermediate of selective tetrodotoxin-sensitive blockers, was efficiently synthesized by a bienzyme cascade system formed by with R-ω-transaminase (ATA117) and an alcohol dehydrogenase (ADH)
Yuan Lu +8 more
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Transfer of a Rational Crystal Contact Engineering Strategy between Diverse Alcohol Dehydrogenases
Crystals, 2021 Protein crystallization can serve as a purification step in biotechnological processes but is often limited by the non-crystallizability of proteins. Enabling or improving crystallization is mostly achieved by high-throughput screening of crystallization
Brigitte Walla +5 more
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Acta Crystallographica Section E, 2009 In the title compound, C5H6N5+·C4H6N3O+·SO42−, the adeninium (AdH+) and cytosinium (CytH+) cations and sulfate dianion are involved in a three-dimensional hydrogen-bonding network with four different modes, viz.
Aouatef Cherouana +4 more
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Alcohol dehydrogenase accentuates ethanol-induced myocardial dysfunction and mitochondrial damage in mice: role of mitochondrial death pathway. [PDF]
PLoS ONE, 2010 Binge drinking and alcohol toxicity are often associated with myocardial dysfunction possibly due to accumulation of the ethanol metabolite acetaldehyde although the underlying mechanism is unknown.
Rui Guo, Jun Ren
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Journal of Experimental & Clinical Cancer Research, 2010 Introduction Women with ductal hyperplasia including usual ductal hyperplasia (UDH) and atypical ductal hyperplasia (ADH) have an increased risk of developing invasive ductal carcinoma (IDC) of breast.
Mao Xiao-yun +5 more
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INAPPROPRIATE ADH SYNDROME OCCURING DURING B-ALL TREATMENT
Hematology, Transfusion and Cell Therapy, 2021 Case report: Inappropriate ADH syndrome is a cause of hyponatremia with increased ADH secretion despite normal plasma osmolality and euvolemic state.There are many related drugs in its etiology.Inappropriate ADH syndrome occured in two B-ALL diagnosed ...
Merih Reis Aras +8 more
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[18F]AlF-NOTA-ADH-1: A new PET molecular radiotracer for imaging of N-cadherin-positive tumors
Frontiers in Oncology, 2023 BackgroundThe cell adhesion molecule (CAM) N-cadherin has become an important target for tumor therapy. The N-cadherin antagonist, ADH-1, exerts significant antitumor activity against N-cadherin-expressing cancers.MethodsIn this study, [18F]AlF-NOTA-ADH ...
Zhenfeng Liu +12 more
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International Journal of Hepatology, 2012 ADH 1 and ADH 3 are major two ADH isozymes in the liver, which participate in systemic alcohol metabolism, mainly distributing in parenchymal and in sinusoidal endothelial cells of the liver, respectively. We investigated how these two ADHs contribute to
Takeshi Haseba +3 more
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Human dental pulp stem cells cultured in serum-free supplemented medium
Frontiers in Physiology, 2013 Growing evidence show that human dental pulp stem cells (DPSCs) could provide a source of adult stem cells for the treatment of neurodegenerative pathologies.
Virginie eBonnamain +8 more
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The alcohol dehydrogenase isoenzyme (ADH I) as a marker of intrahepatic cholestasis of pregnancy
Scientific Reports, 2022 Intrahepatic cholestasis of pregnancy (ICP) is an important pregnancy liver disorder. The alterations of different enzymes activity in the hepatocytes in the course of liver diseases are reflected in an increase in the activity of the corresponding ...
Joanna Piechota +3 more
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