Results 201 to 210 of about 236,653 (360)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Pharmacological Treatment of ADHD

Pharmacological treatment options of ADHD. Complex review of available literature on ADHD pharmacology. Comparison of drugs and their efficacies, safety profiles, mechanisms of action. Suggestions for future directions in ADHD treatment. Brief mention of
Mekky, Madhat H. M.
core  

Attention-deficit/hyperactivity disorder: a systems perspective. A comprehensive qualitative analysis of the literature

, 2001
Plan BAttention-Deficit/Hyperactivity Disorder (ADHD) is a neurological syndrome resulting in problems with self-regulation. ADHD is characterized by inattention and/or hyperactivity-impulsivity which causes impairment in at least two settings.
Reali, Ann T.
core  

The microbiota-gut-brain axis as a modulator of symptom expression in autism spectrum disorder, with exploratory insights into ADHD: evidence from a structured narrative review on paediatric population. [PDF]

Front Child Adolesc Psychiatry
Carta A, Riccio MP, Miola A, Cavassa V, Puci MV, Abbracciavento G, Carucci S, Sambataro F, Bravaccio C, Sotgiu S.   +9 more
europepmc   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Tieto-opas ADHD-lapsen tai nuoren huoltajalle [PDF]

Aktiivisuuden ja tarkkaavuuden häiriöstä on paljon tutkittua tietoa. Opinnäytetyö on rajattu lasten ja nuorten ADHD-diagnoosiin, häiriön tyypilliseen oirekuvaan, sen diagnosointiin sekä hoitomenetelmiin.
Sainio, Joanna, Laula, Santeri
core  

Neural Correlates of Virtual Reality Intervention in Children With Attention-Deficit/Hyperactivity Disorder: A Resting-State fMRI Study Based on Percent Amplitude of Fluctuation. [PDF]

Brain Behav
Yu X, Zhu J, Yang J, Hou H, Mao G, Tang L, Wei F.   +6 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Az ADHD terápiás lehetőségei

, 2013
Bevezetés: Az ADHD a hiperaktivitás-figyelemzavar tünetegyüttesének angol mozaikszava. Gyermek és felnőttkorban is előfordulhat, gyerekeknél jóval gyakoribb. 3 típusa: a figyelemzavaros, a hiperaktív-impulzív és a kevert típus. E betegséggel élő gyerekek
Takács, Enikő
core  

Association Between Task Difficulty Regulation in Game-Based Digital Therapeutics and Attention-Deficit/Hyperactivity Disorder Symptoms in Children: Secondary Analysis of a Randomized Controlled Trial. [PDF]

JMIR Serious Games
Kim JS, Kim SJ, Ryu G, Jun SJ, Park JY, Kim MJ, Han SS, Yoo SH, Kim BI, Lee HJ, Song JH, Hoe HS.   +11 more
europepmc   +1 more source