Results 211 to 220 of about 295,250 (283)

ADHD medications and drug withdrawal: A pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) database. [PDF]

PCN Rep
Ebina T, Iwamoto K, Ikeda M.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Reduced risk of cause-specific hospitalisations and all-cause hospitalisation/mortality during treatment with attention-deficit/hyperactivity disorder medications in the course of bipolar disorder: a Swedish registry-based within-subject cohort study. [PDF]

BMJ Ment Health
Ermis C, Tanskanen A, Corbeil O, Lieslehto J, Vieta E, Correll CU, Mittendorfer-Rutz E, Tiihonen J, Taipale H.   +8 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Risk and resilience: adverse and positive childhood experiences and aggression in adults with and without ADHD. [PDF]

Front Psychiatry
Merscher J, Retz W, Turner D, Retz-Junginger P, Barra S.   +4 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Microbiome signatures correlate with diet-mediated ADHD symptom reduction. [PDF]

Gut Microbes
Hontelez S, Guthrie M, Stobernack T, van Baarlen P, Rousseau C, Boks MP, Pereira RR, Boekhorst J, Kleerebezem M.   +8 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Correction: Attention Deficit Hyperactivity Disorder (ADHD) in Ophthalmologists: Opportunities and Challenges

Ophthalmology and Therapy
Antonia Peilober-Richardson, Rajesh Nair, Rosemary Tattersall, Lauren Gledhill, Shabnum Aslam, Tariq Aslam   +5 more
doaj   +1 more source

Pattern of Oculomotor Findings in Children with Attention Deficit/Hyperactivity Disorder in Relation to Methylphenidate Treatment. [PDF]

J Clin Med
Brogna C, Napoli V, Castellini L, Mirra F, Sestito S, Marsella G, Piscopiello ML, Cima V, Ricci D, Salerni A, Di Cesare G, Brogna P, Romeo DM.   +12 more
europepmc   +1 more source