Results 131 to 140 of about 2,532,336 (393)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Barriers to Compliance with National Guidelines Among Children Hospitalized with Community-Acquired Pneumonia in Vietnam and the Implications

Antibiotics
Background: Community-acquired pneumonia (CAP) is the leading cause of death in infants aged 1–59 months. Concurrent with this, there is a need to prescribe antibiotics wisely in Vietnam due to concerns with rising antimicrobial resistance (AMR ...
Thuy Thi Phuong Nguyen, Huong Thi Thu Vu, Anh Minh Hoang, An Minh Ho, Israel Abebrese Sefah, Brian Godman, Johanna C. Meyer   +6 more
doaj   +1 more source

The association between medication non-adherence and adverse health outcomes in ageing populations: a systematic review and meta-analysis.

British Journal of Clinical Pharmacology, 2019
AIM The aim of this systematic review and meta-analysis was to synthesize the evidence relating to medication non-adherence and its association with health outcomes in people aged ≥50 years. METHODS Seven databases were searched until February 2019 for
C. Walsh, C. Cahir, S. Tecklenborg, C. Byrne, Michael A Culbertson, K. Bennett   +5 more
semanticscholar   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Factors contributing to preventing malaria in children aged 3 to 59 months after the first cycle of seasonal malaria chemoprevention in Tenkodogo Health District of Burkina Faso, July 2020: A prospective cohort study

Journal of Interventional Epidemiology and Public Health
Background: The incidence of malaria in children under 5 years in Burkina Faso was 163 per 1000 with a case fatality of 1.5% in 2018. Despite the implementation of several strategies, malaria incidence increased in Tenkodogo Health District after the ...
Yewayan Larba Berenger Kabore, Watton Rodrigue Diao, Dénis Yelbeogo, Arouna Koidima, Lassane Kafando, Fréderic Dianda, Noaga Sawadogo, Jean-Baptiste Ouedraogo, Yamregma Kabore, Fréderic Kambou, Kodo Albassa, Salfo Ouedraogo, Brahima Traore, Pedwinde Hamadou Seogo   +13 more
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

COVID-19 pandemic versus six “A”s of health care services – accessibility, affordability, availability, appropriateness, adequacy, and adherence

Journal of Family Medicine and Primary Care
Background and Rationale: COVID-19 pandemic resulted in a huge setback in health care sector causing morbidity, mortality, lack of manpower, resources, in hospitals.
Kalidas Sandhya, Priyadharsini R. Palanisamy, R. Sandhya   +2 more
doaj   +1 more source

Adhere today, here tomorrow: oral bacterial adherence [PDF]

Journal of Bacteriology, 1993
P E, Kolenbrander, J, London
openaire   +2 more sources

Psychological, emotional and social impairments are associated with adherence and healthcare spending in type 2 diabetic patients: an observational study [PDF]

, 2019
OBJECTIVE: The aim of the present study was to assess the association among anxiety, depression, stress, social support and emotional abilities with adherence and healthcare spending in type 2 diabetic patients. PATIENTS AND METHODS: Sixty-four patients
Aceto, Paola, Carnovale, Anna, Filippetti, Gloria, Lai, Carlo, Lai, Silvia, Maranghi, Marianna, Pierro, Laura, Renzi, Alessia, Schifano, Ilaria, Tomai, Manuela   +9 more
core  

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source