Results 71 to 80 of about 821,395 (298)

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Preference for Easyhaler® Over Previous Dry Powder Inhalers in Asthma Patients: Results of the DPI PREFER Observational Study

open access: yesPatient Preference and Adherence, 2021
Francisco Javier Alvarez-Gutiérrez,1 Ana Gómez-Bastero Fernández,2 Juan Francisco Medina Gallardo,1 Carlos Campo Sien,3 Paula Rytilä,4 Julio Delgado Romero5 1Unidad de Asma, Hospital Universitario Virgen del Rocio, Sevilla ...
Alvarez-Gutiérrez FJ   +5 more
doaj  

Microgravity and Cell Adherence [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Cell adhesion is an inevitable precondition for enabling cells to assemble into three-dimensional tissues [...]
openaire   +3 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Home-Based Care for Patients with Lysosomal Storage Disease: Experiences in Argentina

open access: yesJournal of Inborn Errors of Metabolism and Screening, 2019
Enzyme replacement therapy (ERT) is a long term treatment for patients who suffer from lysosomal storage disease. A transversal descriptive study was conducted to evaluate advantages and disadvantages of a home-based care program for patients with ...
Maria Victoria Brunelli   +5 more
doaj   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

α-Mangostin hydrogel film with chitosan alginate base for recurrent aphthous stomatitis (RAS) treatment: study protocol for double-blind randomized controlled trial

open access: yesFrontiers in Pharmacology
Background: Recurrent Aphthous Stomatitis (RAS) is a common ulcerative disease of the oral mucosa which is characterized by pain, and recurrent lesions in the oral cavity.
Cszahreyloren Vitamia   +10 more
doaj   +1 more source

Potential Benefits of the Self-Administration of Subcutaneous Methotrexate with Autoinjector Devices for Patients: A Review

open access: yesDrug, Healthcare and Patient Safety, 2021
Jesús Tornero Molina,1 Juan Carlos López Robledillo,2 Núria Casamira Ruiz3 1Department of Rheumatology, Hospital de Guadalajara, Guadalajara, Spain; 2Department of Rheumatology, Hospital del Niño Jesús, Madrid, Spain ...
Tornero Molina J   +2 more
doaj  

To adhere or not to adhere [PDF]

open access: yesCell Adhesion & Migration, 2008
The modulation of cell adhesion is fundamental to the morphogenesis that accompanies proper embryonic development. Cadherins are a large family of calcium-dependent cell adhesion molecules whose spatial and temporal expression is critical to the formation of the neural crest, a unique, multipotent cell type that contributes to the patterning of the ...
openaire   +3 more sources

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