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Bacterial Adhesins: Function and Structure
International Journal of Medical Microbiology, 2000 Specific adhesion to host tissue cells is an essential virulence factor of most bacterial pathogens. The fundamental processes that determine bacterial attachment to host tissue surfaces are mediated by microbial adhesins. Host specificity and tissue tropism are characteristics exhibited by different bacteria and are determined (at least in part) by ...
Mark A. Schembri, Per Klemm, P Klemm
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Journal of Fungi (Basel, Switzerland), 2018 The human fungal pathogen Candida glabrata is causing more and more problems in hospitals, as this species shows an intrinsic antifungal drug resistance or rapidly becomes resistant when challenged with antifungals. C. glabrata only grows in the yeast form, so it is lacking a yeast-to-hyphae switch, which is one of the main virulence factors of C ...
Patrick Van Dijck +2 more
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Adhesin–Receptor Interactions inPasteurellaceae [PDF]
FEMS Microbiology Reviews, 1998 The ability of bacteria to adhere to mucosal epithelium is dependent on the expression of adhesive molecules or structures, called adhesins, that allow attachment of the organisms to complementary molecules on mucosal surfaces, the receptors. Important human and animal pathogens are found among the Pasteurellaceae family which includes Haemophilus ...
Mario Jacques, Sonia-Élaine Paradis
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MAAP: Malarial adhesins and adhesin‐like proteins predictor
Proteins: Structure, Function, and Bioinformatics, 2008AbstractMalaria caused by protozoan parasites belonging to the genus Plasmodium is a dreaded disease, second only to tuberculosis. The emergence of parasites resistant to commonly used drugs and the lack of availability of vaccines aggravates the problem. One of the preventive approaches targets adhesion of parasites to host cells and tissues. Adhesion
Faraz Alam, Ansari +4 more
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FaaPred: A SVM-Based Prediction Method for Fungal Adhesins and Adhesin-Like Proteins
PLoS ONE, 2010 Adhesion constitutes one of the initial stages of infection in microbial diseases and is mediated by adhesins. Hence, identification and comprehensive knowledge of adhesins and adhesin-like proteins is essential to understand adhesin mediated pathogenesis and how to exploit its therapeutic potential.
Dinesh Gupta, Jayashree Ramana
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Clostridium difficile Adhesins
2016Clostridium difficile is responsible for a large spectrum of intestinal diseases ranging from mild diarrhea to fatal colitis depending on the one hand on the strain virulence and on the other on the host. The pathogenesis of C. difficile infection could be seen as a three-step process that takes place after disruption of the digestive microbiota by ...
Séverine, Péchiné +2 more
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Acta Biotechnologica, 1990
AbstractE. coli has got increasing importance as a causative agent of intestinal and extra‐intestinal diseases. In both these infections adhesion of the bacteria to mucous surface cells are initial events for coionization and development of infection. Adhesins are bacterial recognition proteins which specifically interact with carbohydrate moieties of ...
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AbstractE. coli has got increasing importance as a causative agent of intestinal and extra‐intestinal diseases. In both these infections adhesion of the bacteria to mucous surface cells are initial events for coionization and development of infection. Adhesins are bacterial recognition proteins which specifically interact with carbohydrate moieties of ...
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Collagen adhesin–nanoparticle interaction impairs adhesin's ligand binding mechanism
Biochimica et Biophysica Acta (BBA) - General Subjects, 2012Pathogenic bacteria specifically recognize extracellular matrix (ECM) molecules of the host (e.g. collagen, fibrinogen and fibronectin) through their surface proteins known as MSCRAMMs (Microbial Surface Components Recognizing Adhesive Matrix Molecules) and initiate colonization.
Aribam Swarmistha, Devi +4 more
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Current Opinion in Microbiology, 1999
The adherent properties of Candida albicans blastoconidia and germ tubes have long been appreciated, but little is known about the mechanisms responsible for adherence. Recently, three genes, ALA1, ALS1 and HWP1, encoding proteins with adherent properties and motifs consistent with linkage to the beta-1, 6-glucan of C. albicans cell walls have provided
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The adherent properties of Candida albicans blastoconidia and germ tubes have long been appreciated, but little is known about the mechanisms responsible for adherence. Recently, three genes, ALA1, ALS1 and HWP1, encoding proteins with adherent properties and motifs consistent with linkage to the beta-1, 6-glucan of C. albicans cell walls have provided
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VAP-1: an adhesin and an enzyme
Trends in Immunology, 2001Leukocyte extravasation from the blood into tissues is of paramount importance for normal immunosurveillance and in mounting adequate inflammatory responses. Multiple traditional adhesion molecules and chemoattractants on leukocytes and endothelial cells are involved in the emigration process.
M, Salmi, S, Jalkanen
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