Results 61 to 70 of about 33,534 (238)

Identification of Candidate Lyme Disease Vascular Adhesins Supporting Tissue-specific Endothelial Cell Interactions [PDF]

, 2021
Hematogenous dissemination is a crucial step in infectious disease progression, causes most mortality due to bacterial infection, and is central to the spread of tick-borne Lyme disease pathogen Borreliella burgdorferi.
Ly, Amy
core   +1 more source

Oral Bacterial Extracellular Vesicles as Systemic Messengers: A Mouth–Gut–Systemic Axis Paradigm

Gut Medicine, EarlyView.
ABSTRACT Oral microbiome dysbiosis not only associated with localized periodontal disease but also with multiple systemic diseases, including cardiovascular disease, diabetes mellitus, Alzheimer's disease, rheumatoid arthritis, and cancer. However, the efficiency with which intact viable bacteria cross biological barriers to reach distant organs is ...
Yaping Huang, Narisu Hu, Shuang Pan, Sohaib Shujaat, Zhihui Tang, Hongyang Ma   +5 more
wiley   +1 more source

Unraveling the crystal structure of the HpaA adhesin: insights into cell adhesion function and epitope localization of a Helicobacter pylori vaccine candidate

mBio
Helicobacter pylori is a bacterium that exhibits strict host restriction to humans and non-human primates, and the bacterium is widely acknowledged as a significant etiological factor in the development of chronic gastritis, peptic ulcers, and gastric ...
Cyrielle Martini, Victoria Araba, Meriem Beniani, Paula Armoa Ortiz, Mimi Simmons, Mariem Chalbi, Abdelkader Mellouk, Majida El Bakkouri, Charles Calmettes   +8 more
doaj   +1 more source

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

iNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang, Yajuan Wu, Huayang Sheng, Shouhong Jiang, Jinping Cheng, Ye Kuang, Miao Liu, Lei Feng, Yanan Sun, Jinzhi Duan   +9 more
wiley   +1 more source

The role of nonfimbrial adhesins: proteins of outer membrane and lipopolysaccharide in adherence and invasion of bacteria to host cells [PDF]

, 2010
Specific adhesion to host tissue cells is an essential virulence factor of most bacterial pathogens. Adherence is often an essential step in bacterial pathogenesis or infection, required for colonizing a new host.
Szewczyk, Magdalena
core  

New Insights into Bioactive Compounds from the Medicinal Plant Spathodea campanulata P. Beauv. and Their Activity against Helicobacter pylori

Antibiotics, 2020
The medicinal plant Spathodea campanulata P. Beauv. (Bignoniaceae) has been traditionally applied for the prevention and treatment of diseases of the kidney and urinary system, the skin, the gastrointestinal tract, and inflammation in general.
Corinne Raïssa Ngnameko, Lucia Marchetti, Barbara Zambelli, Antonio Quotadamo, Davide Roncarati, Davide Bertelli, Frederic Nico Njayou, Stella I. Smith, Paul F. Moundipa, Maria Paola Costi, Federica Pellati   +10 more
doaj   +1 more source

Zinc‐stabilized stannous fluoride modulates the periodontal microbiome, reducing Fusobacteria, key Gram‐negative species, and overall inflammation within an experimental gingivitis clinical trial

Journal of Periodontology, EarlyView.
Abstract Background This study aimed to evaluate the effects of a dentifrice containing stannous fluoride stabilized with zinc phosphate on subgingival microbiome composition and clinical inflammation during experimental gingivitis, compared with a sodium fluoride control. Methods This investigation was conducted as a secondary analysis of a randomized,
Kristopher A. Kerns, Allison A. Naumann, Lay Y. Soon, Erik L. Hendrickson, Abdelahhad Barbour, Dandan Chen, Harsh M. Trivedi, Michael Glogauer, Jeffrey S. McLean   +8 more
wiley   +1 more source

Expression of candidate adhesins during Leptospira infection.

, 2014
Six hundred nanograms of MBP fusions to L. interrogans candidate adhesins were immobilized on membrane and probed with pre-cleared convalescent sera from patients diagnosed with leptospirosis or control individuals by western blot.
Albert I. Ko (90448), Jenifer Coburn (358772), Beth Hahn (638243), Karen V. Evangelista (638242), David A. Haake (36179), Elsio A. Wunder Jr (473668)   +5 more
core   +1 more source

The fibronectin adhesin of Candida albicans [PDF]

Infection and Immunity, 1994
Candida albicans possesses on its cell surface an adhesin which binds the whole viable fungus to subendothelial extracellular matrix and matrix proteins. The adhesin is composed of 75 to 80% carbohydrate and approximately 20 to 25% protein by weight. High-performance liquid chromatography of material eluted from a fibronectin-agarose affinity column ...
S A, Klotz, R C, Hein, R L, Smith, J B, Rouse   +3 more
openaire   +2 more sources

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source