Results 61 to 70 of about 1,949,140 (330)

Is There a Need for a More Precise Description of Biomolecule Interactions to Understand Cell Function?

open access: yesCurrent Issues in Molecular Biology, 2022
An important goal of biological research is to explain and hopefully predict cell behavior from the molecular properties of cellular components. Accordingly, much work was done to build extensive “omic” datasets and develop theoretical methods, including
Pierre Bongrand
doaj   +1 more source

Polymorphism and bistability in adherent cells

open access: yes, 2013
The optimal shapes attained by contractile cells on adhesive substrates are determined by the interplay between intracellular forces and adhesion with the extracellular matrix.
Banerjee, Shiladitya, Giomi, Luca
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Exposure of Bifidobacterium longum subsp. infantis to Milk Oligosaccharides Increases Adhesion to Epithelial Cells and Induces a Substantial Transcriptional Response [PDF]

open access: yes, 2013
Devon Kavanaugh is in receipt of a Teagasc Walsh Fellowship. The authors would also like to acknowledge the support of Science Foundation Ireland under Grant No.
Butto, Ludovica F.   +8 more
core   +7 more sources

Irisin promotes intestinal epithelial cell proliferation via Wnt/β-catenin and focal adhesion kinase signaling pathways

open access: yesScientific Reports
The regeneration of epithelia is crucial for maintaining intestinal homeostasis. Irisin is an exercise-induced hormone originally found to be secreted by skeletal muscles, thereby regulating energy metabolism.
Arong Gaowa   +4 more
doaj   +1 more source

Loss of contact inhibition of locomotion in the absence of JAM-A promotes entotic cell engulfment

open access: yesiScience, 2022
Summary: Entosis is a cell competition process during which tumor cells engulf other tumor cells. It is initiated by metabolic stress or by loss of matrix adhesion, and it provides the winning cell with resources derived from the internalized cell. Using
Mariel F. Schwietzer   +8 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Adhesion theory review [PDF]

open access: yes, 1972
Bonding theories reviewed include physical adsorption, hydrogen bonding, chemisorption and surface energy; bond failure mechanisms include phase discontinuity, swelling and corrosion.
Delollis, N. J.
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Depth profile of thin coating through surface and interfacial cutting analysis of UV curing system

open access: yesMaterials & Design, 2019
There are various thin coating technologies, among which the UV coating technology is attracting attention in next-generation industries. In order to utilize the UV coating system stably, it is necessary to analyze and address the problems of surface ...
Ji-Won Park   +6 more
doaj   +1 more source

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