Results 61 to 70 of about 893,418 (338)
Torsional Instabilities in the Delamination of Soft Adhesives [PDF]
Soft adhesive contacts are ubiquitous in nature and are increasingly used in synthetic systems, such as flexible electronics and soft robots, due to their advantages over traditional joining techniques. While methods to study the failure of adhesives typically apply tensile loads to the adhesive joint, less is known about the performance of soft ...
arxiv
Effect of adhesion geometry and rigidity on cellular force distributions [PDF]
The behaviour and fate of tissue cells is controlled by the rigidity and geometry of their adhesive environment, possibly through forces localized to sites of adhesion. We introduce a mechanical model that predicts cellular force distributions for cells adhering to adhesive patterns with different geometries and rigidities.
arxiv +1 more source
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen+13 more
wiley +1 more source
A role for Rap2 in recycling the extended conformation of LFA-1 during T cell migration
Summary T lymphocytes make use of their major integrin LFA-1 to migrate on surfaces that express ICAM-1 such as blood vessels and inflamed tissue sites.
Paula Stanley, Sharon Tooze, Nancy Hogg
doaj +1 more source
On shear adhesion of adhesive fibrils
Natural fibrillar adhesives, widely recognized for their strong and reversible adhesion, have inspired the development of numerous synthetic adhesive systems applied in diverse fields. These biological and bioinspired adhesive fibrils exhibit a wide range of aspect ratios spanning four orders of magnitude.
Linghu, Changhong+4 more
openaire +2 more sources
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha+6 more
wiley +1 more source
The adhesion of microcapsules to an attractive contact potential is studied theoretically. The axisymmetric shape equations are solved numerically. Beyond a universal threshold strength of the potential, the contact radius increases like a square root of the strength.
Reimar Finken, Peter Graf, Udo Seifert
openaire +4 more sources
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini+11 more
wiley +1 more source
Numerous factors affecting the interactions between healthcare professionals in the workplace demand a comprehensive understanding if the quality of patient healthcare is to be improved.
Eiji Kawamoto+7 more
doaj +1 more source
Surface profiles with zero and finite adhesion force and adhesion instabilities [PDF]
A simple but general analysis of stability of axis-symmetric adhesive contacts is provided. Adhesion is considered in the JKR-approximation. Depending on the shape of the contacting bodies, various scenarios are possible, including vanishing adhesive force, complete contact as well as transitions between these states.
arxiv