Results 51 to 60 of about 1,357,755 (309)

Irisin promotes intestinal epithelial cell proliferation via Wnt/β-catenin and focal adhesion kinase signaling pathways

open access: yesScientific Reports
The regeneration of epithelia is crucial for maintaining intestinal homeostasis. Irisin is an exercise-induced hormone originally found to be secreted by skeletal muscles, thereby regulating energy metabolism.
Arong Gaowa   +4 more
doaj   +1 more source

EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth

open access: yesJournal of Hematology & Oncology, 2017
Background Activated protein C/endothelial protein C receptor (APC/EPCR) axis is physiologically involved in anticoagulant and cytoprotective activities in endothelial cells.
Naiara Perurena   +11 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Role of Plasma Surface Treatments on Wetting and Adhesion

open access: yes, 2009
There are many current and emerging wetting and adhesion issues which require an additional surface processing to enhance interfacial surface properties.
Sparavigna, Amelia Carolina   +4 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Adhesion of the Composite Resins to the Typodont Tooth Materials [PDF]

open access: yes, 2005
P(論文)In order to examine a possibility of typodont tooth materials for adhesive restoration approach in place of human tooth, the adhesive strength and the durability of 3 kinds of raw materials presently used for the typodont tooth were examined in ...
9003   +5 more
core  

A role for Rap2 in recycling the extended conformation of LFA-1 during T cell migration

open access: yesBiology Open, 2012
Summary T lymphocytes make use of their major integrin LFA-1 to migrate on surfaces that express ICAM-1 such as blood vessels and inflamed tissue sites.
Paula Stanley, Sharon Tooze, Nancy Hogg
doaj   +1 more source

The Role of Innate Lymphoid Cells in the Regulation of Immune Homeostasis in Sepsis-Mediated Lung Inflammation

open access: yesDiagnostics, 2020
Septic shock/severe sepsis is a deregulated host immune system response to infection that leads to life-threatening organ dysfunction. Lung inflammation as a form of acute lung injury (ALI) is often induced in septic shock.
Yuichi Akama   +7 more
doaj   +1 more source

Is There a Need for a More Precise Description of Biomolecule Interactions to Understand Cell Function?

open access: yesCurrent Issues in Molecular Biology, 2022
An important goal of biological research is to explain and hopefully predict cell behavior from the molecular properties of cellular components. Accordingly, much work was done to build extensive “omic” datasets and develop theoretical methods, including
Pierre Bongrand
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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