Results 1 to 10 of about 5,944,904 (315)
The FVIII activity in patients treated with several extended half-life FVIII (EHL-FVIII) agents different when various activated partial thromboplastin time (APTT) reagents were used.
Hideo Wada MD, PhD +7 more
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Identification of a membrane-less compartment regulating invadosome function and motility
Depletion of liprin-α1, ERC1 or LL5 scaffolds inhibits extracellular matrix degradation by invasive cells. These proteins co-accumulate near invadosomes in NIH-Src cells, identifying a novel invadosome–associated compartment distinct from the core and ...
Kristyna Sala +4 more
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Rho and Rab Family Small GTPases in the Regulation of Membrane Polarity in Epithelial Cells
Membrane polarity, defined as the asymmetric distribution of lipids and proteins in the plasma membrane, is a critical prerequisite for the development of multicellular tissues, such as epithelia and endothelia.
Klaus Ebnet +5 more
doaj +1 more source
Septic shock/severe sepsis is a deregulated host immune system response to infection that leads to life-threatening organ dysfunction. Lung inflammation as a form of acute lung injury (ALI) is often induced in septic shock.
Yuichi Akama +7 more
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During cancer progression, cells lose their original tissue contacts, move through the extracellular matrix (ECM), enter into the lymphatic and/or blood system, extravasate, and ultimately form new tumors. Therefore, tumor cells inevitably experience alterations in cell-cell and cell-ECM adhesion and the transformation activities of tumor cells are ...
Eok-Soo Oh +3 more
openaire +3 more sources
The regeneration of epithelia is crucial for maintaining intestinal homeostasis. Irisin is an exercise-induced hormone originally found to be secreted by skeletal muscles, thereby regulating energy metabolism.
Arong Gaowa +4 more
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Junctional Adhesion Molecules (JAMs): The JAM-Integrin Connection
Junctional adhesion molecules (JAMs) are cell surface adhesion receptors of the immunoglobulin superfamily. JAMs are involved in a variety of biological processes both in the adult organism but also during development.
Daniel Kummer, Klaus Ebnet
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Numerous factors affecting the interactions between healthcare professionals in the workplace demand a comprehensive understanding if the quality of patient healthcare is to be improved.
Eiji Kawamoto +7 more
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Rolling adhesion on vascular surfaces is the first step in recruiting circulating leukocytes, hematopoietic progenitors, or platelets to specific organs or to sites of infection or injury. Rolling requires the rapid yet balanced formation and dissociation of adhesive bonds in the challenging environment of blood flow.
Rodger P, McEver, Cheng, Zhu
openaire +2 more sources
Gap junction-mediated regulation of endothelial cellular stiffness
Endothelial monolayers have shown the ability to signal each other through gap junctions. Gap junction-mediated cell-cell interactions have been implicated in the modulation of endothelial cell functions during vascular inflammation.
Takayuki Okamoto +7 more
doaj +1 more source

