Expression of the neural cell adhesion NCAM in endocrine cells of the ovary [PDF]
, 1991 In the adult mammalian ovary morphogenesis and differentiation processes are under hormonal control and, thus, occur in a highly regulated way during the sexual cycle.
Lahr, G. +2 more
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Journal of Cellular Physiology, 2007 AbstractThe complex interactions of cells with extracellular matrix (ECM) play crucial roles in mediating and regulating many processes, including cell adhesion, migration, and signaling during morphogenesis, tissue homeostasis, wound healing, and tumorigenesis. Many of these interactions involve transmembrane integrin receptors.
Allison L, Berrier, Kenneth M, Yamada
openaire +2 more sources
Differential Roles of Dendritic Cells in Expanding CD4 T Cells in Sepsis
Biomedicines, 2019 Sepsis is a systemically dysregulated inflammatory syndrome, in which dendritic cells (DCs) play a critical role in coordinating aberrant immunity. The aim of this study is to shed light on the differential roles played by systemic versus mucosal DCs in ...
Samuel Darkwah +6 more
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FAK Structure and Regulation by Membrane Interactions and Force in Focal Adhesions
Biomolecules, 2020 Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase with key roles in the regulation of cell adhesion migration, proliferation and survival. In cancer FAK is a major driver of invasion and metastasis and its upregulation is associated with poor
Paula Tapial Martínez +2 more
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Loss of contact inhibition of locomotion in the absence of JAM-A promotes entotic cell engulfment
iScience, 2022 Summary: Entosis is a cell competition process during which tumor cells engulf other tumor cells. It is initiated by metabolic stress or by loss of matrix adhesion, and it provides the winning cell with resources derived from the internalized cell. Using
Mariel F. Schwietzer +8 more
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The Evolution of Cell Adhesion [PDF]
The Journal of Cell Biology, 2000 Multicellular organisms clearly require mechanisms for intercellular communication and, perhaps even more basically, for intercellular cohesion. The most primitive sponges and coelenterates depend on cell adhesion for their organismal organization; so do insects, nematodes and vertebrates ...
R O, Hynes, Q, Zhao
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Leydig cells express neural cell adhesion molecules in vivo and in vitro [PDF]
, 1992 The neural cell adhesion molecule (NCAM) polypeptides are expressed by numerous tissues during embryonic development, where they are involved in cell-cell interactions.
Lahr, G. +7 more
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PSPC1 Potentiates IGF1R Expression to Augment Cell Adhesion and Motility
, 2020 Paraspeckle protein 1 (PSPC1) overexpression in cancers is known to be the pro-metastatic switch of tumor progression associated with poor prognosis of cancer patients.
Yaw-Dong Lang +3 more
core +1 more source
Multi-scale modelling of the dynamics of cell colonies : insights into cell-adhesion forces and cancer invasion from in silico simulations [PDF]
, 2015 Studying the biophysical interactions between cells is crucial to understanding how normal tissue develops, how it is structured and also when malfunctions occur.
Ramis-Conde, Ignacio +3 more
core +1 more source
Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1
Communications Biology, 2023 Scribble (Scrib) is a multidomain polarity protein and member of the leucine-rich repeat and PDZ domain (LAP) protein family. A loss of Scrib expression is associated with disturbed apical-basal polarity and tumor formation.
Eva-Maria Thüring +9 more
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