Results 51 to 60 of about 5,944,904 (315)

Supramolecular structure of a new family of circular proteoglycans mediating cell adhesion in sponges [PDF]

, 2000
Jarchow J, Fritz J, Anselmetti D, et al. Supramolecular structure of a new family of circular proteoglycans mediating cell adhesion in sponges. Journal of structural biology.
Fritz, Jürgen, Gerosa, Daniela, Burger, Max M., Calabro, Anthony, Fernandez-Busquets, Xavier, Hascall, Vincent C., Jarchow, Janina, Anselmetti, Dario ; https://orcid.org/   +7 more
core   +1 more source

MicroRNA Profiles in Intestinal Epithelial Cells in a Mouse Model of Sepsis

Cells, 2023
Sepsis is a systemic inflammatory disorder that leads to the dysfunction of multiple organs. In the intestine, the deregulation of the epithelial barrier contributes to the development of sepsis by triggering continuous exposure to harmful factors ...
Siqingaowa Caidengbate, Yuichi Akama, Anik Banerjee, Khwanchanok Mokmued, Eiji Kawamoto, Arong Gaowa, Louise D. McCullough, Motomu Shimaoka, Juneyoung Lee, Eun Jeong Park   +9 more
doaj   +1 more source

A parallel-plate flow chamber to study initial cell adhesion on a nanofeatured surface [PDF]

, 2004
Cells in the human body come across many types of information, which they respond to. Both material chemistry and topography of the surface where they adhere have an effect on cell shape, proliferation, migration, and gene expression.
K. McGhee, C. Wilkinson, Wilkinson, C., McGhee, K., A. Curtis, E. Martines, Curtis, A.S.G., Martines, E.   +7 more
core   +1 more source

Junctional adhesion molecule (JAM)-C deficient C57BL/6 mice develop a severe hydrocephalus [PDF]

, 2012
The junctional adhesion molecule (JAM)-C is a widely expressed adhesion molecule regulating cell adhesion, cell polarity and inflammation. JAM-C expression and function in the central nervous system (CNS) has been poorly characterized to date.
Michel Mittelbronn, Imhof, Beat A., Aurrand-Lions, Michel, Michel Aurrand-Lions, Deutsch, Urban, Karl H Plate, Adams, Ralf H, Liebner, Stefan, Schäfer, Julia, Enzmann, Gaby, Plate, Karl H, Urban Deutsch, Beat A Imhof, Adams, Ralf Heinrich, Mittelbronn, Michel, Imhof, Beat, Mittelbronn, Michel Guy André, Plate, Karl, Gaby Enzmann, Ralf H Adams, Engelhardt, Britta, Britta Engelhardt, Lena Wyss, Stefan Liebner, Plate, Karl H., Julia Schäfer, Wyss, Lena, Adams, Ralf H.   +27 more
core   +3 more sources

Structural basis for interdomain communication in SHIP2 providing high phosphatase activity

eLife, 2017
SH2-containing-inositol-5-phosphatases (SHIPs) dephosphorylate the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P3) and play important roles in regulating the PI3K/Akt pathway in physiology and disease.
Johanne Le Coq, Marta Camacho-Artacho, José Vicente Velázquez, Clara M Santiveri, Luis Heredia Gallego, Ramón Campos-Olivas, Nicole Dölker, Daniel Lietha   +7 more
doaj   +1 more source

Melanoma-associated adhesion molecule MUC18/MCAM (CD146) and transcriptional regulator Mader in normal human CNS [PDF]

, 1998
The proteins MUC18 and Mader have been identified as markers of tumor progression in melanoma cells, MUC18, also known as MCAM (melanoma cell adhesion molecule) and as CD146 (endothelial antigen), is a cell adhesion molecule belonging to the ...
Müller, Norbert, Johnson, Judith P., Kirsch, Kathrin H., Hampel, Harald, Schwarz, Markus J., Ackenheil, Manfred, Penning, Randolph, Körschenhausen, Dirk   +7 more
core   +1 more source

RP1 is a phosphorylation target of CK2 and is involved in cell adhesion [PDF]

, 2013
RP1 (synonym: MAPRE2, EB2) is a member of the microtubule binding EB1 protein family, which interacts with APC, a key regulatory molecule in the Wnt signalling pathway.
Renner, Christoph, Frank Stenner, Kleber Sascha, Göttig Stephan, Andreas Wadle (24358), Christoph Renner, Frank Stenner (24360), Alexander Knuth, Axel Mischo, Er Knuth, Stefan Bauer (24356), Zweifel, Martin, Michael Faust, Stephan Göttig (430017), Bauer, Stefan, Andreas Wadle, Faust Michael, Sascha Kleber (24359), Knuth, Alexander, Martin Zweifel, Martin Zweifel (430020), Heike Liewen, Mischo Axel, Stephan Göttig, Michael Faust (331617), Christoph Renner (24366), Markuly Norbert, Zweifel Martin, Stenner Frank, Wadle, Andreas, Kleber, Sascha, Markuly, Norbert, Axel Mischo (430019), Norbert Markuly, Reinhard Henschler (369547), Wadle Andreas, Norbert Markuly (430018), Liewen Heike, Henschler Reinhard, Alexander Knuth (11104), Heike Liewen (430016), Göttig, Stephan, Stenner, Frank, Sascha Kleber, Bauer Stefan, Renner Christoph, Reinhard Henschler, Liewen, Heike, Faust, Michael, Mischo, Axel, Stefan Bauer, Henschler, Reinhard, Knuth Alexander   +52 more
core   +2 more sources

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source