Results 71 to 80 of about 5,944,904 (315)

Neural cell adhesion molecules in rat endocrine tissues and tumor cells: distribution and molecular analysis [PDF]

, 1993
The adhesive properties of neural cell adhesion molecules (NCAMs) can be modified by alternative splicing of the primary transcript or posttranslational modifications.
Lahr, G., Bucher, S., Wille, W., Gratzl, Manfred, Barthels, D., Mayerhofer, Artur   +5 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Bond tilting and sliding friction in a model of cell adhesion

, 2007
As a simple theoretical model of a cell adhering to a biological interface, we consider a rigid cylinder moving in a viscous shear flow near a wall. Adhesion forces arise through intermolecular bonds between receptors on the cell and their ligands on the
Jensen, O. E.; id_orcid, Reboux, S., Richardson, Giles, Jensen, O.E., Richardson, G.   +4 more
core   +1 more source

Tendon is covered by a basement membrane epithelium that is required for cell retention and the prevention of adhesion formation [PDF]

, 2011
The ability of tendons to glide smoothly during muscle contraction is impaired after injury by fibrous adhesions that form between the damaged tendon surface and surrounding tissues. To understand how adhesions form we incubated excised tendons in fibrin
Al-Youha Sarah, Susan H Taylor, Van Agtmael Tom, Van Agtmael, T., Wong, J., Lu Yinhui, Wong Jason, Kadler Karl E., Duncan A. McGrouther, Jason Wong, Taylor, Susan H, Kadler, Karl E; id_orcid, Al-Youha, Sarah, McGrouther, Duncan A, Agarwal, S., Duncan A McGrouther, Karl E Kadler, McGrouther Duncan A., Lu, Y., Yinhui Lu, Karl E. Kadler, Al-Youha, S., Sarah Al-Youha, Taylor Susan H., Kadler, K.E., Lu, Yinhui, Tom Van Agtmael, Taylor, S.H., McGrouther, D.A., Susan H. Taylor, Van Agtmael, Tom, Wong, Jason; id_orcid   +31 more
core   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Breast Cancer-Derived Microparticles Reduce Cancer Cell Adhesion, an Effect Augmented by Chemotherapy

, 2020
Tumor cell heterogeneity is primarily dictated by mutational changes, sometimes leading to clones that undergo a metastatic switch. However, little is known about tumor heterogeneity following chemotherapy perturbation.
Leonel M. Sagredo, Tamar Geiger, Shimrit Avraham, Dvir Shechter, David Loven, Yuval Shaked, Abhishek Mukherjee, Haguy Wolfenson, Michal Harel, Elad Prinz, Veronique Orian-Rousseau   +10 more
core   +1 more source

Carbohydrate-carbohydrate interaction provides adhesion force and specificity for cellular recognition and adhesion [PDF]

, 2004
Carbohydrates at the cell surface have been proposed as mediators in cell-cell recognition events involved in embryogenesis, metastasis, and other proliferation processes by calcium-dependent carbohydrate to carbohydrate interactions.
Bucior, Iwona
core   +1 more source

GSK-J4 Inhibition of KDM6B Histone Demethylase Blocks Adhesion of Mantle Cell Lymphoma Cells to Stromal Cells by Modulating NF-κB Signaling [PDF]

, 2023
Multiple signaling pathways facilitate the survival and drug resistance of malignant B-cells by regulating their migration and adhesion to microenvironmental niches.
Laia Sadeghi, Wright, Anthony P H, Sadeghi, L,, Sadeghi, Laia, Wright, APH, Anthony P. H. Wright   +5 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

High-resolution snapshots of the talin auto-inhibitory states suggest roles in cell adhesion and signaling

Nature Communications
Talin regulates crucial cellular functions, including cell adhesion and motility, and affects human diseases. Triggered by mechanical forces, talin plays crucial roles in facilitating the formation of focal adhesions and recruiting essential focal ...
Erumbi S. Rangarajan, Julian L. Bois, Scott B. Hansen, Tina Izard   +3 more
doaj   +1 more source