Results 1 to 10 of about 18,190 (273)

Circulating Irisin Levels in Patients with Chronic Plaque Psoriasis [PDF]

Biomolecules, 2022
Irisin is an adipo-myokine, mainly synthetized in skeletal muscles and adipose tissues, that is involved in multiple processes. Only a few studies have evaluated serum irisin in psoriatic patients.
Francesca Ambrogio, Lorenzo Sanesi, Angela Oranger, Chiara Barlusconi, Manuela Dicarlo, Patrizia Pignataro, Roberta Zerlotin, Paolo Romita, Elvira Favoino, Gerardo Cazzato, Nicoletta Cassano, Gino Antonio Vena, Caterina Foti, Maria Grano   +13 more
doaj   +2 more sources

The association of circulating irisin with metabolic risk factors in Chinese adults: a cross-sectional community-based study

BMC Endocrine Disorders, 2019
Background Irisin is a myokine that leads to increased energy expenditure by stimulating the browning of white adipose tissue. We aimed to investigate the association of serum irisin levels with metabolic parameters in middle aged Chinese population ...
Lizhi Tang, Yuzhen Tong, Fang Zhang, Guilin Chen, Yun Cong Zhang, John Jobin, Nanwei Tong   +6 more
doaj   +2 more sources

FNDC5/irisin, a molecular target for boosting reward-related learning and motivation [PDF]

, 2018
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Gesztelyi, Rudolf, Juhász, Béla, Papp, Csaba, Tajti, Gábor, Zsuga, Judit   +4 more
core   +3 more sources

Irisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative stress

Redox Biology, 2019
Current management of liver ischemia-reperfusion (I/R) injury is mainly based on supportive care and no specific treatment is available. Irisin, a recently identified hormone, plays pivotal roles in energy expenditure and oxidative metabolism; however ...
Jianbin Bi, Jia Zhang, Yifan Ren
exaly   +3 more sources

Engineered long-acting Irisin-albumin binding domain fusion protein for enhanced anti-inflammatory efficacy in lipopolysaccharide-induced systemic inflammation [PDF]

Communications Biology
Irisin is a peptide hormone with notable anti-inflammatory and metabolic regulatory effects but has limited clinical utility due to its extremely short plasma half-life (< 1 h).
Jicun Zhu, Yujie Zhang, Xinwei Wang, Lei Peng, Xiaojia Ma, Zan Qiu, Zirui Kang, Fangyuan Zheng, Xiaoyu Zhang, Mengyuan Song, Jia Du, Yuan Shi, Lie Yu, Chenxi Gu, Jianxiang Shi   +14 more
doaj   +2 more sources

Salivary and serum irisin in healthy adults before and after exercise

European Journal of Translational Myology, 2023
Irisin is an exercise-induced cytokine mainly secreted by myocytes. Circulating level of irisin can increase in response to acute exercise, promoting pleiotropic effects on health.
Sara Missaglia, Ester Tommasini, Paola Vago, Claudio Pecci, Christel Galvani, Andrea Silvestrini, Alvaro Mordente, Daniela Tavian   +7 more
doaj   +2 more sources

Circulating Irisin Levels Are Not Affected by Coffee Intake: A Randomized Controlled Trial [PDF]

, 2014
Irisin, secreted by skeletal muscle and possibly fat, is hypothesized to play an important role in modulating energy expenditure, obesity and metabolism.
Huh, Joo Young, Mantzoros, Christos S., Park, Kyung Hee, Peter, Patricia R., Wedick, Nicole M.   +4 more
core   +18 more sources

Role of Irisin in Myocardial Infarction, Heart Failure, and Cardiac Hypertrophy

Cells, 2021
Irisin is a myokine derived from the cleavage of fibronectin type III domain-containing 5. Irisin regulates mitochondrial energy, glucose metabolism, fatty acid oxidation, and fat browning.
Ming-Yun Ho, Chao-Yung Wang
doaj   +1 more source

Relationship between serum irisin level, all-cause mortality, and cardiovascular mortality in peritoneal dialysis patients

Kidney & Blood Pressure Research, 2023
Introduction: This study aimed to investigate the prospective role of serum irisin-a novel adipo-myokine-in all-cause mortality and cardiovascular (CV) mortality in patients on peritoneal dialysis (PD).
Sijia Zhou, Wen Tang, Xiaoxiao Wang, Qingfeng Han, Qiong Bai, Aihua Zhang   +5 more
doaj   +1 more source

Roles and Mechanisms of Irisin in Attenuating Pathological Features of Osteoarthritis

Frontiers in Cell and Developmental Biology, 2021
To investigate the effects and mechanisms of irisin, a newly discovered myokine, in cartilage development, osteoarthritis (OA) pathophysiology and its therapeutic potential for treating OA we applied the following five strategical analyses using (1 ...
Xiangfen Li, Xiangfen Li, Xiaofang Zhu, Hongle Wu, Hongle Wu, Thomas E. Van Dyke, Thomas E. Van Dyke, Xiaoyang Xu, Elise F. Morgan, Wenyu Fu, Wenyu Fu, Chuanju Liu, Chuanju Liu, Qisheng Tu, Dingming Huang, Jake Chen   +15 more
doaj   +1 more source