Circulating irisin levels are positively associated with metabolic risk factors in sedentary subjects. [PDF]
PLoS ONE, 2015 A physically active life-style plays an independent role in the protection against type 2 diabetes and cardiovascular diseases. Irisin, a novel exercise-induced myokine, activates thermogenesis in rodents through increasing beige fat cells abundance ...
María Moreno +9 more
doaj +1 more source
Effects of physical activity on the link between PGC-1a and FNDC5 in muscle, circulating Ιrisin and UCP1 of white adipocytes in humans: A systematic review [PDF]
, 2017 Background: Exercise may activate a brown adipose-like phenotype in white adipose tissue. The aim of this systematic review was to identify the effects of physical activity on the link between peroxisome proliferator-activated receptor gamma coactivator ...
Dinas, Petros C. +6 more
core +2 more sources
Dose-dependent tandem responses of osteoblasts during osteogenesis
Medicine in Novel Technology and Devices, 2023 Irisin, a myokine mainly secreted from contracted skeleton muscle, plays a profound role in bone formation and remodeling. Although irisin has been revealed to elevate bone mass in vivo, details whether there is a dose-dependent relationship between ...
Yuwei Zhang +4 more
doaj +1 more source
Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk [PDF]
, 2019 BACKGROUND: Muscle wasting from chronic kidney disease (CKD) or from defective insulin signalling results in morbidity and, ultimately, mortality. We have identified an endogenous mediator of insulin resistance, signal regulatory protein alpha (SIRPα ...
Dong, Jiangling +7 more
core +2 more sources
Expression, purification and biological characterisation of recombinant human irisin (12.5 kDa)
Journal of Genetic Engineering and Biotechnology, 2018 Fibronectin type III domain containing 5 (FNDC5) is a transmembrane protein. Upon cleavage, it yields a peptide called irisin that is supposedly bind to an unknown receptor and facilitates browning of white adipose tissue (WAT).
Kalpana Panati +5 more
doaj +1 more source
3-Center Studie zur Untersuchung von Auswirkungen der Ganzkörpervibrationstherapie bei Patienten mit Lungenfibrose: eine randomisiert kontrollierte Studie. Effekte auf serumspezifische Biomarker, Inflammationsparameter, gesundheitsbezogene Lebensqualität und den 6-Minutengehtest als Nebenergebnis. [PDF]
, 2020 Hintergrund: Zahlreiche wissenschaftliche Studien deuten auf positive trainingstherapeutische Effekte bei Patienten mit interstitiellen Lungenerkrankungen (ILD ) hin.
Kölpin, Janina
core +1 more source
Relationship between Irisin Concentration and Serum Cytokines in Mother and Newborn. [PDF]
PLoS ONE, 2016 Irisin is considered to be a myokine and adipokine that may also participate in reproductive functions, as it increases significantly throughout pregnancy.
Maria Hernandez-Trejo +3 more
doaj +1 more source
Gaziantep Üniversitesi Spor Bilimleri Dergisi, 2022 Gelişmiş ve gelişmekte olan ülkelerdeki şehir hayatının hareketsiz yaşamı, besinsel ürünlere kolay ulaşabilmeyi ve fas food kültürünü yaygınlaştırdığı görülmektedir. Yeni yaşam tarzı hem halk sağlığını tehdit etmekte hem de sistemik metabolik fonksiyon bozukluklarına kılavuzluk ederek obezite gibi hastalıkların yaygınlaşmasına neden olmaktadır.
Salih ÖNER, Yavuz YASUL
openaire +3 more sources
Role of irisin in Chinese patients with hypothyroidism: an interventional study
Journal of International Medical Research, 2019 Objective Irisin is a myokine that greatly affects energy expenditure and systemic metabolism. While thyroid hormone is likely associated with irisin, a direct relationship remains to be fully elucidated.
Ning Yang +6 more
doaj +1 more source
Journal of Techniques, 2022 Evidence suggests that Irisin, a peptide hormone, may play a role in lipid metabolism, insulin resistance, and obesity. On the other hand, its role in type 2 diabetic Mellitus [T2DM] in humans is uncertain.
Takwa Al Koloob Ali Chachan +2 more
doaj +1 more source