Results 61 to 70 of about 7,364 (142)
Health Science Reports, Volume 9, Issue 6, June 2026.ABSTRACT Background and Aims Osteosarcopenia, defined as the coexistence of osteoporosis and sarcopenia, is an emerging geriatric syndrome linked to the musculoskeletal decline associated with aging. It is correlated with an increased risk of falls, fractures, disability, and mortality.
Javeria Taj +6 more
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Encephalopathy: Cause, Pathogenesis, and Treatment
MedComm, Volume 7, Issue 6, June 2026.Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv +7 more
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Med Research, Volume 2, Issue 2, Page 280-308, June 2026.White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang +12 more
wiley +1 more source
Irisin in Reproduction: Its Roles and Therapeutic Potential in Male and Female Fertility Disorders
BiomoleculesThe current study focused on identifying the potential of irisin in mammalian reproduction. The established role of irisin, a proteolytic product of FNDC5, in adipose tissue browning, energy metabolism, and thermogenesis suggests its role in reproductive
Muhammad Ibrahim Khan +2 more
doaj +1 more source
The Journal of Physiology, Volume 604, Issue 12, Page 4815-4833, 15 June 2026.Abstract figure legend Acute aerobic exercise induces LGALS1, FSTL1, OGN and C1QTNF3 in both skeletal muscle and adipose tissue, with LGALS1 and FSTL1 upregulation corresponding to increased circulating galectin‐1 and follistain‐like 1. Red and yellow brick bars represent the contribution of skeletal muscle and adipose tissue, respectively, integrating
Jaeseung Song +5 more
wiley +1 more source
Evolutionary Insights into Irisin/FNDC5: Roles in Aging and Disease from Drosophila to Mammals
BiomoleculesThe Irisin/FNDC5 protein family has emerged as a pivotal link between exercise and the prevention of age-associated diseases. Irisin is highly expressed during exercise from skeletal and cardiac muscle cells, playing a critical role in mediating systemic
Kiwon Lee, Myungjin Kim
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Comparison of irisin hormone expression between thyroid cancer tissues and oncocytic variant cells
Cancer Management and Research, 2019 Kader Ugur,1 Suleyman Aydin,2 Tuncay Kuloglu,3 Gokhan Artas,4 Mehmet Ali Kocdor,5 İbrahim Sahin,2,6 Meltem Yardim,2 İbrahim Hanefi Ozercan41Department of Endocrinology and Metabolism Disease, School of Medicine, Firat University, Elazig, Turkey ...
Ugur K +7 more
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Clinical and Experimental Hypertension, 2017 The aims of this study are to observe irisin and urotensin II (UII) levels in serum and placenta in normal pregnant and preeclamptic women and investigate the relationship between expressions irisin and UII, and their association with blood pressure.
Li-Jie Zhang +3 more
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Irisin alleviated sepsis via enhancing macrophage phagocytosis and reducing inflammation levels
Frontiers in ImmunologyBackgroundThe treatment of sepsis relies on antibiotics following infection; however, the emergence of resistant bacteria necessitates the development of new therapeutic agents.
Zeen Gong +10 more
doaj +1 more source
The Serum Irisin Level in Non-Diabetic Patients with Chronic Kidney Disease
Turkish Journal of Nephrology, 2019 OBJECTIVE: Metabolic activity in patients with chronic kidney disease (CKD) is characterized by increased energy expenditure, protein loss, and catabolic processes. Irisin is a recently discovered thermogenic protein that causes energy expenditure.
İhsan ATEŞ +4 more
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