Results 81 to 90 of about 4,586 (139)
Frontiers in Endocrinology, 2019 Whether irisin concentrations are associated with physical activity (PA) and sedentary time (ST) remains unknown. The role of irisin on cardiometabolic health among children has been contradictory and scarce.
Li Cai +9 more
doaj +1 more source
Aging Cell, Volume 25, Issue 10, October 2026.Mitochondrial fission‐fusion imbalance contributes to age‐related cardio‐cerebral diseases like Alzheimer's disease, Parkinson's disease, Cerebral Infarction, Arteriosclerosis, Myocardial Infarction, Cardiac valve disease, Hypertension, and Cardiomyopathy. This review summarizes its regulatory mechanisms and interventions.
Yuyao Yin, Zijian Li
wiley +1 more source
Irisin Mitigates Doxorubicin-Induced Cardiotoxicity by Reducing Oxidative Stress and Inflammation via Modulation of the PERK-eIF2α-ATF4 Pathway [PDF]
Zilong Zhang,* Xiaolin Yu,* Jie Li, Xin Shen, Wenbo Fu, Yongguo Liu, Xiangyu Dong, Zhao Wang Department of Cardiology, Cardiac and Pan - Vascular Medicine Center, People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang, People’s Republic ...
Liu Y +7 more
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Mechanistic Pathways of Wound Healing: From Hemostasis to Scar‐Free Regeneration
Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.ABSTRACT Wound healing is the critical process regulated through a harmonious coordination of cellular, molecular, pathological, and systemic communications. Normally, healing occurs in four overlapping phases, which are modified and controlled by various growth factor interactions and signaling pathways.
Devadass Jessy Mercy +2 more
wiley +1 more source
, 2017 Yukari Sugiyama, Kazuhisa Asai, Kazuhiro Yamada, Yuko Kureya, Naoki Ijiri, Tetsuya Watanabe, Hiroshi Kanazawa, Kazuto Hirata Department of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka, Japan Background: Cigarette ...
Hirata K +7 more
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Structure and Function Studies of Irisin
, 2021 Irisin is an exercise hormone induced by muscles. It is activating downstream signaling by binding its precursor FNDC5 or CD81 receptor complex with \uce\ub1V/\uce\ub21 integrin.
Li, Yi-Tzu
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CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.Peripheral nerve injury induces dynamic cortical plasticity, driven by molecular mechanisms such as BDNF and neurotransmitter systems. This review synthesizes subtype‐specific plasticity patterns: compressive injuries trigger rapid reorganization, while metabolic neuropathies lead to maladaptive changes.
Cong Cheng +8 more
wiley +1 more source
, 2017 Irisin is a polypeptide hormone derived from the proteolytic cleavage of fibronectin-type III domain-containing 5 (FNDC5) protein. Once released to circulation upon exercise or cold exposure, irisin stimulates browning of white adipose tissue (WAT) and ...
Michel M Dard +11 more
core +1 more source
Exercise‐Induced Myonectin Protects Against Cerebral Ischemia–Reperfusion Injury
CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.Exercise‐induced myonectin protects against cerebral ischemia–reperfusion injury. Myonectin knockout abolishes exercise benefits, whereas recombinant administration reduces cerebral infarct size. Mechanistically, myonectin activates PI3K/AKT/mTOR signaling, thereby suppressing excessive neuronal autophagy and microglial‐driven neuroinflammation ...
Jing Zhang +7 more
wiley +1 more source
Serum Irisin Levels are Inversely Correlated with Acute Ischaemic Stroke Incidence: Implications for Early Diagnosis in Southern China [PDF]
Fengshan Ouyang,1,2 Sheng Chen,1 Shuhuan Li,3 Lanyuan Liu,4 Senhong Guan,1 Zhaohan Yan,1 Shumin Wu,5 Yunying Zeng,1 Jiemei Liu,2 Jiankai Zhong1 1Department of Cardiology, Shunde Hospital, Southern Medical University (The First People’s Hospital of Shunde)
Liu J +9 more
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