Results 81 to 90 of about 18,190 (273)

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

Experimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti, Bergita Ganse, Nicola A. Maffiuletti, Rob C. I. Wüst, Gustav J. Strijkers, Andy Sanderson, Hans Degens   +6 more
wiley   +1 more source

Irisin and the Metabolic Phenotype of Adults with Prader-Willi Syndrome. [PDF]

PLoS ONE, 2015
Hyperphagia, low resting energy expenditure, and abnormal body composition contribute to severe obesity in Prader Willi syndrome (PWS). Irisin, a circulating myokine, stimulates "browning" of white adipose tissue resulting in increased energy expenditure
Harry J Hirsch, Itai Gross, Yehuda Pollak, Talia Eldar-Geva, Varda Gross-Tsur   +4 more
doaj   +1 more source

Ontogeny and thermogenic role for sternal fat in female sheep [PDF]

, 2017
Brown adipose tissue acting through a unique uncoupling protein (UCP1) has a critical role in preventing hypothermia in new-born sheep but is then considered to rapidly disappear during postnatal life.
Albrecht, Alexander, Alexander, Atit, Bal, Barquissau, Basse, Belinda A. Henry, Bispham, Blessing, Blondin, Bloor, Cantile, Cao, Christian, Christodoulides, Clapham, Clarke, Clarke, Clarke, de Jong, Ellis, Elsen, Forner, Gburcik, Harms, Helen Budge, Henry, Henry, Henry, Henry, Horvath, Hotta, Hunt, Iain J. Clarke, John-Paul Fuller-Jackson, Kiskinis, Kooijman, Kurose, Lean, Lee, Lee, Loomis, Macotela, Mark Birtwistle, Mark Pope, Michael E. Symonds, Moldes, Møller, Nedergaard, Nedergaard, Nygaard, Ojha, Ootsuka, Petrovic, Pope, Rachael Loughnan, Ramayo-Caldas, Reham Alagal, Rosell, Rowland, Sacks, Sanchez-Gurmaches, Sanchez-Gurmaches, Scheele, Scotney, Seale, Sechen, Shan, Shinoda, Symonds, Symonds, Symonds, Symonds, Symonds, Symonds, Symonds, Timmons, van Marken Lichtenbelt, Vergnes, Virtanen, Viv Perry, Wellik, Xue, Yamamoto   +84 more
core   +2 more sources

Effects of a single strength training session on the peripheral concentrations of irisin in trained men [PDF]

, 2023
Larissa Ferreira, Marcos Antônio Borges, Gabriela Nagata, Lucélia Scarabeli Silva Barroso, Heliana B. Fernandes, Antônio Felipe Souza-Gomes, Aline Silva de Miranda, Albená Nunes-Silva   +7 more
openalex   +1 more source

In vitro muscle contraction: A technical review on electrical pulse stimulation in C2C12 cells

Experimental Physiology, EarlyView.
Abstract Electrical pulse stimulation (EPS) of skeletal muscle cells is increasingly used to model exercise In vitro. The murine C2C12 myotube system has become a common platform for such studies, yet wide variability in EPS protocols hampers reproducibility and cross‐study comparisons.
Mark R. C. van de Meene, Anita M. van den Hoek, Roeland Hanemaaijer, Lars Verschuren, Jelle C. B. C. de Jong   +4 more
wiley   +1 more source

Is Irisin an Anticarcinogenic Peptide?

Medicine Science | International Medical Journal, 2015
Prostate cancer is the most common type of cancer in males. There has been currently no therapy to cure various types of cancer, and hence, studies aiming to develop cancer treatment are important and have been ongoing. Irisin is a hormone, which regulates body weight and metabolism, including insulin resistance and is thought to have beneficial ...
Suat, Tekin, Yavuz, Erden, Suleyman, Sandal, Bayram, Yilmaz   +3 more
openaire   +3 more sources

Modification of reinforcement learning processes in mood disorders in asthma patients [PDF]

, 2018
Az orbitofrontális kortex (OFC) integratív funkciója kiemelkedő jelentőségű a megerősítéses tanulási döntéshozatalban: • a mediális OFC a jel-kontextus kongruencia alapján kontextuskereteket azonosít • a laterális OFC hozzáférést biztosít a ...
Szilasi, Magdolna Emma
core  

Seven days of warm‐water immersion enhances resting irisin and BDNF, but not klotho, in older men

Experimental Physiology, EarlyView.
Abstract We examined whether seven consecutive days of warm‐water immersion could elevate resting and exercise‐induced levels of brain‐derived neurotrophic factor (BDNF), irisin and klotho in older adults. These biomarkers support cognitive and metabolic health, but their levels decline with age.
Joel M Garrett, James J McCormick, Kelli E King, Kristina‐Marie T Janetos, Nathalie V Kirby, Fergus K O'Connor, Glen P Kenny   +6 more
wiley   +1 more source

Irisin-loaded Porous Silica Nanoparticles Enhance Bone Healing in High Cholesterol Diet-induced Medaka Fish Model

Precision Nanomedicine
Irisin is a myokine that stimulates browning of white adipocytes and enhances cortical bone mass during physical exercise. However, its short half-life limits its therapeutic potential, making sustained delivery systems desirable for bone tissue ...
Prashant Sadanandan, Silja Krishnan, Manzoor Koyakutty, Manitha Nair   +3 more
doaj   +1 more source

Ultrastructural analysis of changes in neurons of the mouse internal anal sphincter during ageing [PDF]

, 2013
Gastrointestinal disorders, including chronic constipation, faecal impaction and incontinence, are a major cause of morbidity in the ...
Colyer, Frances, Davies, Heather, Gamage, Prasanna, Ranson, Richard N., Saffrey, M.Jill, Yeoman, Mark   +5 more
core