Results 101 to 110 of about 4,586 (139)

Irisin in Reproduction: Its Roles and Therapeutic Potential in Male and Female Fertility Disorders

open access: yesBiomolecules
The current study focused on identifying the potential of irisin in mammalian reproduction. The established role of irisin, a proteolytic product of FNDC5, in adipose tissue browning, energy metabolism, and thermogenesis suggests its role in reproductive
Muhammad Ibrahim Khan   +2 more
doaj   +1 more source

Circulating Sclerostin and Irisin Are Related and Interact with Gender to Influence Adiposity in Adults with Prediabetes

open access: yesInternational Journal of Endocrinology, 2014
Objectives. Sclerostin, an osteocyte-specific protein, has been found to be related to adiposity and glucose metabolism. Irisin, a myokine, can affect browning of white fat and influence glucose and energy homeostasis.
Theerawut Klangjareonchai   +7 more
doaj   +1 more source

Delivery vehicle of muscle-derived irisin based on silk/calcium silicate/sodium alginate composite scaffold for bone regeneration

open access: yes, 2019
Xianzhen Xin,1,* Jiannan Wu,1,* Ao Zheng,1 Delong Jiao,1 Yang Liu,2 Lingyan Cao,1 Xinquan Jiang1 1Department of Prosthodontics, Shanghai Engineering Research Center of Advanced Dental Technology and Materials, Shanghai Key Laboratory of Stomatology and ...
Cao L   +6 more
core  

Irisin promotes C2C12 cell proliferation.

open access: yes, 2019
(A, B) C2C12 cells were treated with irisin for indiciated times in culture medium (A) without FBS or (B) with FBS. Cell proliferation (%) was measured by MTS assay. Data are represented as the means ± SD (n = 3).
Jangho Lee (4742889)   +4 more
core   +1 more source

Relationship of irisin with disease severity and dopamine uptake in Parkinson's disease patients

open access: yesNeuroImage: Clinical
Background: This study was designed to investigate the relationship of irisin with the severity of Parkinson’s disease (PD) and dopamine (DOPA) uptake in patients with PD and to understand the role of irisin in PD.
Xiaoxue Shi   +11 more
doaj   +1 more source

Irisin Attenuates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension via Ubiquitin‐Mediated Regulation of ENO1

open access: yesAdvanced Science
Pulmonary vascular remodeling, which current therapeutic targets fail to alleviate disease severity, plays a key role in pulmonary arterial hypertension (PAH).
Na Sun   +15 more
doaj   +1 more source

Evolutionary Insights into Irisin/FNDC5: Roles in Aging and Disease from Drosophila to Mammals

open access: yesBiomolecules
The Irisin/FNDC5 protein family has emerged as a pivotal link between exercise and the prevention of age-associated diseases. Irisin is highly expressed during exercise from skeletal and cardiac muscle cells, playing a critical role in mediating systemic
Kiwon Lee, Myungjin Kim
doaj   +1 more source

Is Irisin an Anticarcinogenic Peptide?

open access: yes, 2015
Prostate cancer is the most common type of cancer in males. There has been currently no therapy to cure various types of cancer, and hence, studies aiming to develop cancer treatment are important and have been ongoing.
Yavuz, Erden   +7 more
core   +1 more source

Is irisin really a neuroendocrine (f)actor?

open access: yes
Irisin was identified as a peptide hormone in 2012. The most important known physiological effect of irisin is that it activates uncoupling protein 1 and converts white adipose tissue to brown adipose tissue.
Sandal, Suleyman   +2 more
core   +1 more source

Plasma concentration of irisin.

open access: yes, 2015
Plasma concentration of irisin measured following singular sessions of intense endurance (END) or heavy strength training (STR), or on a control day (CON) without training. Data are mean values ± SEM.
Håvard Nygaard (703531)   +7 more
core   +1 more source

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