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Exercise training mode effects on myokine expression in healthy adults: A systematic review with meta-analysis [PDF]

open access: yesJournal of Sport and Health Science
Background: The benefits of exercise are well known; however, many of the underlying molecular mechanisms are not fully understood. Skeletal muscle secretes myokines, which mediate muscle–organ crosstalk.
Dennis Taaffe   +2 more
exaly   +6 more sources

Evidence for acute contraction-induced myokine secretion by C2C12 myotubes. [PDF]

open access: yesPLoS ONE, 2018
Skeletal muscle is considered a secretory organ that produces bioactive proteins known as myokines, which are released in response to various stimuli.
Yasuro Furuichi   +4 more
doaj   +2 more sources

Effects of exercise on myokine gene expression in horse skeletal muscles [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2019
Objective To examine the regulatory effects of exercise on myokine expression in horse skeletal muscle cells, we compared the expression of several myokine genes (interleukin 6 [IL-6], IL-8, chemokine [C-X-C motif] ligand 2 [CXCL2], and chemokine [C-C ...
Hyo Gun Lee   +6 more
doaj   +3 more sources

Exercise-myokine relationships in osteoarthritis [PDF]

open access: yesJournal of Translational Medicine
Background The pathogenesis and progression of osteoarthritis (OA) involve a multidimensional interplay of biomechanical abnormalities, metabolic disturbances, and inflammatory cascades.
Yiwen Zhang   +4 more
doaj   +2 more sources

Advances in the research on myokine-driven regulation of bone metabolism

open access: yesHeliyon
The traditional view posits that bones and muscles interact primarily through mechanical coupling. However, recent studies have revealed that myokines, proteins secreted by skeletal muscle cells, play a crucial role in the regulation of bone metabolism ...
Sheng Lu
exaly   +3 more sources

Ergogenic effects of caffeine are mediated by myokines

open access: yesFrontiers in Sports and Active Living, 2022
Exercise has long been known to effectively improve and enhance skeletal muscle function and performance. The favorable effects of exercise on remote organs other than skeletal muscle are well known, but the underlying mechanism has remained elusive ...
Shingo Takada   +4 more
doaj   +1 more source

The impact of dietary intervention on myokines: a narrative review [PDF]

open access: yesPharmacia
This review elucidates the role of dietary factors in influencing myokine secretion, complementing the recognized benefits of physical activity on metabolic health.
Yavor Assyov   +12 more
doaj   +3 more sources

Artificial intelligence in decoding muscle–organ crosstalk: Unveiling myokine networks and therapeutic frontiers [PDF]

open access: yesJournal of Exercise & Organ Cross Talk
Skeletal muscle functions as an endocrine organ, secreting myokines that mediate crosstalk with organs like the brain, liver, adipose tissue, and vascular system, influencing metabolism, inflammation, and disease progression.
Ehsan Arabzadeh   +2 more
doaj   +1 more source

Skeletal muscle stretching as a mechanotransductive trigger for myokine release: A narrative review [PDF]

open access: yesJournal of Exercise & Organ Cross Talk
Skeletal muscle functions as an endocrine organ by releasing myokines—cytokines and peptides that mediate systemic physiological adaptations.
Hossein Shirvani   +2 more
doaj   +1 more source

Cardiovascular Response and Serum Interleukin-6 Level in Concentric Vs. Eccentric Exercise [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: Cardiovascular Disease (CVD) is a leading cause of morbidity and mortality in India. Resistance exercise is strongly recommended for implementation in CVD prevention programs.
Mayank Agarwal   +5 more
doaj   +1 more source

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