Results 41 to 50 of about 11,761 (240)

FGF21 as Modulator of Metabolism in Health and Disease

Frontiers in Physiology, 2019
Fibroblast growth factor 21 (FGF21) is a hormone that regulates important metabolic pathways. FGF21 is expressed in several metabolically active organs and interacts with different tissues.
Caterina Tezze, Caterina Tezze, Vanina Romanello, Vanina Romanello, Marco Sandri, Marco Sandri, Marco Sandri, Marco Sandri   +7 more
doaj   +1 more source

Muscle signals to the rescue

eLife, 2020
The skeletal muscle of fruit flies communicates with other organs to prevent the accumulation of too much fat and to protect adults against obesity.
Arely V Diaz, Tânia Reis
doaj   +1 more source

Physical exercise associated with NO production: Signaling pathways and significance in health and disease

Frontiers in Cell and Developmental Biology, 2015
Here we review available data on nitric oxide (NO)-mediated signaling in skeletal muscle during physical exercise. Nitric oxide modulates skeletal myocyte function, hormone regulation, and local microcirculation.
Elena Yu Dyakova, Leonid V Kapilevich, Victor G Shylko, Sergey V Popov, Yana eAnfinogenova   +4 more
doaj   +1 more source

The Potential Role of Myokines/Hepatokines in the Progression of Neuronal Damage in Streptozotocin and High-Fat Diet-Induced Type 2 Diabetes Mellitus Mice

Biomedicines, 2022
Background: Diabetes is highly prevalent, and the number of patients with diabetic sarcopenia and cognitive impairment has grown, leading to decreased quality of life.
Heaji Lee, Yunsook Lim
doaj   +1 more source

Irisin treatment improves healing of dystrophic skeletal muscle [PDF]

, 2017
Background: Irisin is an exercise induced myokine that is shown to promote browning of adipose tissue and hence, increase energy expenditure. Furthermore, our unpublished results indicate that Irisin improves myogenic differentiation and induces skeletal
Ge, Xiaojia, Kambadur, Ravi, McFarlane, Craig, Reza, Musarrat Maisha, Sharma, Mridula, Sim, Chu Ming, Subramaniyam, Nathiya   +6 more
core   +2 more sources

Exercise and Conjugated Linoleic Acid Supplementation Induce Changes in the Composition of Liver Fatty Acids

Frontiers in Physiology, 2019
Exercise and supplementation with conjugated linoleic acid (CLA) are used to reduce body weight and to improve health. Applied together, they may exert a synergistic effect. However, the effects of exercise and CLA supplementation on liver metabolism are
Adriana Mika, Adriana Mika, Aleksandra Czumaj, Piotr Stepnowski, Filippo Macaluso, Filippo Macaluso, Filippo Macaluso, Giulio Spinoso, Rosario Barone, Rosario Barone, Valentina Di Felice, Valentina Di Felice, Tomasz Sledzinski   +12 more
doaj   +1 more source

Profiling of adenine‐derived signaling molecules, cytokinins, in myotubes reveals fluctuations in response to lipopolysaccharide‐induced cell stress

Physiological Reports, 2023
Cytokinins (CTKs) are a diverse collection of evolutionarily conserved adenine‐derived signaling molecules classically studied as phytohormones; however, their roles and production have been less studied in mammalian systems.
Stephanie W. Tobin, Dev Seneviratne, Lorna Phan, Mark Seegobin, Alexander L. Rico, Beth Westby, Anna Kisiala, Sanela Martic, Craig R. Brunetti, R. J. Neil Emery   +9 more
doaj   +1 more source

Paracrine cross-talk between skeletal muscle and macrophages in exercise by PGC-1α-controlled BNP [PDF]

, 2017
Activation of resident and infiltrating immune cells is a central event in training adaptation and other contexts of skeletal muscle repair and regeneration.
Beer, Markus, Eisele, Petra S., Furrer, Regula, Handschin, Christoph, Schmidt, Alexander   +4 more
core   +1 more source

Editorial: Myokines, Adipokines, Cytokines in Muscle Pathophysiology [PDF]

Frontiers in Physiology, 2020
Individual striated muscle fibers communicate in both a paracrine and endocrine fashion and are also involved in the crosstalk with other tissues and organs such as the adipose tissue, immune system, liver, pancreas, bones, and brain (Delezie andHandschin, 2018).
Valentina Di Felice, Dario Coletti, Dario Coletti, Dario Coletti, Marilia Seelaender   +4 more
openaire   +3 more sources

A low-calorie diet raises β-aminoisobutyric acid in relation to glucose regulation and leptin independent of exercise in women with obesity

Frontiers in Physiology, 2023
Introduction: β-aminoisobutyric acid (BAIBA) is a suggested cytokine secreted from skeletal muscles that regulates insulin sensitivity, pancreatic function, and fat oxidation. However, no studies to date have examined if a low-calorie diet (LCD) or LCD +
Habiba Faiz, Steven K. Malin, Steven K. Malin, Steven K. Malin, Steven K. Malin, Steven K. Malin   +5 more
doaj   +1 more source