Results 41 to 50 of about 8,085 (246)

Muscle signals to the rescue

eLife, 2020
The skeletal muscle of fruit flies communicates with other organs to prevent the accumulation of too much fat and to protect adults against obesity.
Arely V Diaz, Tânia Reis
doaj   +1 more source

The Potential Role of Myokines/Hepatokines in the Progression of Neuronal Damage in Streptozotocin and High-Fat Diet-Induced Type 2 Diabetes Mellitus Mice

Biomedicines, 2022
Background: Diabetes is highly prevalent, and the number of patients with diabetic sarcopenia and cognitive impairment has grown, leading to decreased quality of life.
Heaji Lee, Yunsook Lim
doaj   +1 more source

Physical exercise associated with NO production: Signaling pathways and significance in health and disease

Frontiers in Cell and Developmental Biology, 2015
Here we review available data on nitric oxide (NO)-mediated signaling in skeletal muscle during physical exercise. Nitric oxide modulates skeletal myocyte function, hormone regulation, and local microcirculation.
Elena Yu Dyakova, Leonid V Kapilevich, Victor G Shylko, Sergey V Popov, Yana eAnfinogenova   +4 more
doaj   +1 more source

Extracellular Vesicles: Delivery Vehicles of Myokines [PDF]

Frontiers in Physiology, 2019
Movement and regular physical activity are two important factors that help the human body prevent, reduce and treat different chronic diseases such as obesity, type 2 diabetes, heart diseases, hypertension, sarcopenia, cachexia and cancer. During exercise, several tissues release molecules into the blood stream, and are able to mediate beneficial ...
Eleonora Trovato, Valentina Di Felice, Valentina Di Felice, Rosario Barone, Rosario Barone   +4 more
openaire   +4 more sources

Exercise and Conjugated Linoleic Acid Supplementation Induce Changes in the Composition of Liver Fatty Acids

Frontiers in Physiology, 2019
Exercise and supplementation with conjugated linoleic acid (CLA) are used to reduce body weight and to improve health. Applied together, they may exert a synergistic effect. However, the effects of exercise and CLA supplementation on liver metabolism are
Adriana Mika, Adriana Mika, Aleksandra Czumaj, Piotr Stepnowski, Filippo Macaluso, Filippo Macaluso, Filippo Macaluso, Giulio Spinoso, Rosario Barone, Rosario Barone, Valentina Di Felice, Valentina Di Felice, Tomasz Sledzinski   +12 more
doaj   +1 more source

Profiling of adenine‐derived signaling molecules, cytokinins, in myotubes reveals fluctuations in response to lipopolysaccharide‐induced cell stress

Physiological Reports, 2023
Cytokinins (CTKs) are a diverse collection of evolutionarily conserved adenine‐derived signaling molecules classically studied as phytohormones; however, their roles and production have been less studied in mammalian systems.
Stephanie W. Tobin, Dev Seneviratne, Lorna Phan, Mark Seegobin, Alexander L. Rico, Beth Westby, Anna Kisiala, Sanela Martic, Craig R. Brunetti, R. J. Neil Emery   +9 more
doaj   +1 more source

Myokines: Crosstalk and Consequences on Liver Physiopathology

Nutrients, 2023
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease mainly characterized by the hepatic accumulation of lipid inducing a deregulation of β-oxidation. Its advanced form is non-alcoholic steatohepatitis (NASH), which, in addition to lipid accumulation, induces hepatocellular damage, oxidative stress and fibrosis that can progress to ...
Aurore Dumond Bourie, Jean-Baptiste Potier, Michel Pinget, Karim Bouzakri   +3 more
openaire   +2 more sources

Chronic Low or High Nutrient Intake and Myokine Levels

, 2022
Inadequate nutrient availability has been demonstrated to be one of the main factors related to endocrine and metabolic dysfunction. We investigated the role of inadequate nutrient intakes in the myokine levels of runners.
Fontes-Junior, Antônio Alves, Sierra, Ana Paula Renno, Barbeiro, Hermes Vieira, Ana Paula Renno Sierra, Cury-Boaventura, Maria Fernanda, Manoel, Leticia Aparecida da Silva, Cesar Augustus Zocoler de Sousa, de Menezes, Duane Cardoso, de Sousa, Cesar Augustus Zocoler, de Souza, Heraldo Possolo, Vinicius Alves Rocha, Antônio Alves Fontes-Junior, Hermes Vieira Barbeiro, Leticia Aparecida da Silva Manoel, Maria Fernanda Cury-Boaventura, Duane Cardoso de Menezes, Heraldo Possolo de Souza, Paz, Inês Assis, Rocha, Vinicius Alves, Inês Assis Paz   +19 more
core   +1 more source

A low-calorie diet raises β-aminoisobutyric acid in relation to glucose regulation and leptin independent of exercise in women with obesity

Frontiers in Physiology, 2023
Introduction: β-aminoisobutyric acid (BAIBA) is a suggested cytokine secreted from skeletal muscles that regulates insulin sensitivity, pancreatic function, and fat oxidation. However, no studies to date have examined if a low-calorie diet (LCD) or LCD +
Habiba Faiz, Steven K. Malin, Steven K. Malin, Steven K. Malin, Steven K. Malin, Steven K. Malin   +5 more
doaj   +1 more source

The role of myokines in muscle health and disease [PDF]

Current Opinion in Rheumatology, 2016
Purpose of review This article updates on the concept that muscle-derived cytokines (myokines) play important roles in muscle health and disease. Recent findings Interleukin-6 (IL-6) is released from normal skeletal muscle in response to exercise, mediating both anti-inflammatory ...
Lightfoot, AP, Cooper, RG
openaire   +3 more sources