Results 21 to 30 of about 8,845 (203)
Frontiers in Veterinary Science, 2022 The peripartum period in dairy cows is frequently associated with excessive lipolysis due to Negative Energy Balance (NEB). These metabolic disorders are the cause of various pathologies.
Mathilde Daudon +5 more
doaj +1 more source
Irisin – a myth rather than an exercise-inducible myokine [PDF]
, 2015 The myokine irisin is supposed to be cleaved from a transmembrane precursor, FNDC5 (fibronectin type III domain containing 5), and to mediate beneficial effects of exercise on human metabolism. However, evidence for irisin circulating in blood is largely
Thiede, Bernd +23 more
core +2 more sources
Frontiers in Cardiovascular Medicine, 2020 Chronic diseases, including heart failure (HF), are often accompanied with skeletal muscle abnormalities in both quality and quantity, which are the major cause of impairment of the activities of daily living and quality of life.
Shingo Takada +3 more
doaj +1 more source
The Controversial Role of Irisin in Clinical Management of Coronary Heart Disease
Frontiers in Endocrinology, 2021 Irisin, a PGC1α-dependent myokine, was once believed to have beneficial effects induced by exercise. Since its first discovery of adipose browning in 2012, multiple studies have been trying to explore the metabolic functions of irisin, such as glucose ...
Wen-Lu Ou-Yang +10 more
doaj +1 more source
48 h stimulated myokine treatment downregulated ACE2 protein levels in 16HBE14o.
, 2022 Anti-ACE2 ELISA revealed a ~53.0% downregulation of ACE2 protein with stimulated myokine treatment.
Beth Parker (1792180) +6 more
core +1 more source
Voluntary exercise and cardiac remodeling in a myocardial infarction model
Open Medicine, 2020 We investigated the effects of voluntary exercise after myocardial infarction (MI) on cardiac function, remodeling, and inflammation. Male C57BL/6J mice were divided into the following four groups: sedentary + sham (Sed-Sh), sedentary + MI (Sed-MI ...
Shahi Hamad Al +13 more
doaj +1 more source
The Physiological Role of Irisin in the Regulation of Muscle Glucose Homeostasis
Endocrines, 2021 Irisin is a myokine that primarily targets adipose tissue, where it increases energy expenditure and contributes to the beneficial effects of exercise through the browning of white adipose tissue. As our knowledge has deepened in recent years, muscle has
Naohiro Yano, Yu Tina Zhao, Ting C. Zhao
doaj +1 more source
Novel methods for cold exposure of skeletal muscle in vivo and in vitro show temperature-dependent myokine production [PDF]
, 2021 Proteins secreted from skeletal muscle serving a signalling role have been termed myokines. Many of the myokines are exercise factors, produced and released in response to muscle activity.
Honkanen, Susanna Kyllikki +6 more
core +2 more sources
FGF21 as Modulator of Metabolism in Health and Disease
Frontiers in Physiology, 2019 Fibroblast growth factor 21 (FGF21) is a hormone that regulates important metabolic pathways. FGF21 is expressed in several metabolically active organs and interacts with different tissues.
Caterina Tezze +7 more
doaj +1 more source
eLife, 2020 The skeletal muscle of fruit flies communicates with other organs to prevent the accumulation of too much fat and to protect adults against obesity.
Arely V Diaz, Tânia Reis
doaj +1 more source