Results 71 to 80 of about 18,190 (273)
Circulating Irisin Is Reduced in Male Patients with Type 1 and Type 2 Myotonic Dystrophies
Frontiers in Endocrinology, 2017 ContextMyotonic dystrophies (DM) are dominantly inherited muscle disorders characterized by myotonia, muscle weakness, and wasting. The reasons for sarcopenia in DMs are uncleared and multiple factors are involved. Irisin, a positive hormone regulator of
Elena Dozio +13 more
doaj +1 more source
The Role of Interventional Irisin on Heart Molecular Physiology
Pharmaceuticals, 2022 Irisin, encoded by the FNDC5 (fibronectin type III domain containing 5) gene, is a novel myokine that has been implicated as an essential mediator of exercise benefits. Effects of irisin on heart physiology is still ambiguous.
Foad Alzoughool +5 more
doaj +1 more source
Relationship between serum irisin, glycemic indices, and renal function in type 2 diabetic patients. [PDF]
, 2017 Introduction: Irisin is a novel peptide that plays notable role in human and animal biology and physiology. It has been reported that irisin may improve insulin resistance and related disturbances.
Ahmadi, Ali. +3 more
core
Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor? [PDF]
, 2013 FNDC5 (fibronectin domain-containing [protein] 5) was initially discovered and characterized by two groups in 2002. In 2011 FNDC5 burst into prominence as the parent of irisin, a small protein containing the fibronectin type III domain.
Erickson, HP
core +1 more source
Journal of Periodontal Research, EarlyView.Irisin is an extracellular peptide stimulated by exercise and could act as both a biomarker and mediate the positive impact of exercise. This scoping review synthesizes human evidence on irisin variations in non‐communicable diseases, showing an increase of irisin in saliva and gingival tissues in periodontitis, potentially reflecting reparative or ...
Larysa Saboya Cavalotti Perdonsini +4 more
wiley +1 more source
Irisin promotes C2C12 myoblast proliferation via ERK-dependent CCL7 upregulation.
PLoS ONE, 2019 Irisin is an exercise-induced myokine that has various physiological functions, such as roles in energy expenditure, glucose/lipid metabolism, and muscle development.
Jangho Lee +4 more
doaj +1 more source
Frontiers in Endocrinology, 2023 BackgroundIrisin plays a role in bone-muscle crosstalk, but the relationship between the serum irisin level and bone microarchitecture remains unknown.ObjectiveThis study aimed to investigate the relationships between serum irisin level and fall risk ...
Hanting Liang +10 more
doaj +1 more source
Obesity Reviews, EarlyView.ABSTRACT Obesity as a chronic and multifactorial disease requires a multidisciplinary team acting together in a holistic multitarget intervention. Multidisciplinary therapy targeting obesity and its complications includes physical exercise, nutritional, and behavior counseling.
Ana Raimunda Dâmaso +7 more
wiley +1 more source
Role of irisin in bone diseases
Frontiers in Endocrinology, 2023 Bone diseases are common among middle-aged and elderly people, and harm to activities of daily living (ADL) and quality of life (QOL) for patients. It is crucial to search for key regulatory factors associated with the development of bone diseases and explore potential therapeutic targets for bone diseases.
Ruobing Zhao +5 more
openaire +3 more sources
Irisin exhibits neuroprotection by preventing mitochondrial damage in Parkinson’s disease
npj Parkinson's Disease, 2023 Exercise has been proposed as an effective non-pharmacological management for Parkinson’s disease (PD) patients. Irisin, a recently identified myokine, is increased by exercise and plays pivotal roles in energy metabolism.
Xi Zhang +8 more
doaj +1 more source