Results 11 to 20 of about 4,586 (139)

Irisin: Still chasing shadows

Molecular Metabolism, 2020
Objective: Considerable uncertainty remains regarding the veracity of measuring myokine irisin more than seven years after its original description. Unresolved issues include the nature of transcription of the irisin precursor fibronectin type III domain
Elke Albrecht, Lisa Schering, Friedrich Buck, Konrad Vlach, Hans-Christof Schober, Christian A. Drevon, Steffen Maak   +6 more
doaj   +2 more sources

Expression and Function of Synthetic Dimeric Exercise-Induced Cytokine Irisin-Irisin

康复学报, 2023
ObjectiveStudies have shown that the exercise-induced cytokine Irisin functions were as a dimer, so tandem Irisin-Irisin mock dimers were designed to explore the similarities and differences between recombinant Irisin-Irisin expressed by Escherichia coli
LIU Fengying, HUANG Yide, LIN Jia, CHEN Xuequn, WANG Qingshui, LIN Yao   +5 more
doaj   +2 more sources

Comparison of irisin hormone expression between thyroid cancer tissues and oncocytic variant cells

Cancer Management and Research, 2019
Kader Ugur,1 Suleyman Aydin,2 Tuncay Kuloglu,3 Gokhan Artas,4 Mehmet Ali Kocdor,5 İbrahim Sahin,2,6 Meltem Yardim,2 İbrahim Hanefi Ozercan41Department of Endocrinology and Metabolism Disease, School of Medicine, Firat University, Elazig, Turkey ...
Ugur K, Aydin S, Kuloglu T, Artas G, Kocdor MA, Sahin İ, Yardim M, Hanifi Ozercan I   +7 more
doaj   +1 more source

Irisin, Two Years Later [PDF]

, 2013
In January 2012, Boström and colleagues identified a new muscle tissue secreted peptide, which they named irisin, to highlight its role as a messenger that comes from skeletal muscle to other parts of the body.
Cristina Contreras, Amparo Romero-Picó, López, Miguel, CONTRERAS JIMENEZ, CRISTINA, Diéguez, Carlos, López Pérez, Miguel A., Diéguez González, Carlos, Romero Picó, Amparo, Marta G. Novelle, Garrido Novelle, Marta, Miguel López, Carlos Diéguez   +11 more
core   +1 more source

Exploring the role of esketamine in alleviating depressive symptoms in mice via the PGC-1α/irisin/ERK1/2 signaling pathway

Scientific Reports, 2023
Esketamine provides an immediate and noticeable antidepressant effect, although the underlying molecular processes are yet unclear. Irisin induced by aerobic exercise has been implicated in the alleviation of depressive symptoms, whether irisin ...
Na Hu, Xuemei Chen, Chengchuan Chen, Xing Liu, Peng Yi, Tianhao Xu, Jing Jia, Jianguo Feng, Chunxiang Zhang, Xiaobin Wang   +9 more
doaj   +1 more source

Serum irisin levels increase in girls with central precocious puberty not dependent on BMI: a pilot study

Endocrine Connections, 2022
Objective: The objective of this study is to investigate the role of seru m irisin level in diagnosis of central precocious puberty (CPP) in girls and its major determinants.
Yanfei Chen, Mei Li, Binrong Liao, Jingzi Zhong, Dan Lan   +4 more
doaj   +1 more source

Irisin Exerts Inhibitory Effect on Adipogenesis Through Regulation of Wnt Signaling

Frontiers in Physiology, 2019
Irisin is an exercise-induced myokine known to induce adipocyte browning through induction of uncoupling protein 1. Recent studies have reported that irisin is also an adipokine.
Eun Bi Ma, Namood E. Sahar, Moonsup Jeong, Joo Young Huh   +3 more
doaj   +1 more source

Irisin in liver cirrhosis [PDF]

, 2020
Background: Sarcopenia is a prevalent muscle abnormality characterized by progressive and generalized loss of skeletal muscle mass and strength, common among patients with decompensated advanced chronic liver disease (dACLD).
Wojciech Marlicz, Nabrdalik, Katarzyna, Gumprecht, Janusz, Janusz Gumprecht, Menżyk, Tomasz, Kukla, Michał, Marlicz, Wojciech, Dominika Stygar, Skonieczna, Magdalena, Aleksandra Derra, Hudy, Dorota, Tomas Koller, Michał Kukla, Magdalena Skonieczna, Skladany, Lubomir, Koulaouzidis, Anastasios, Koller, Tomas, Lubomir Skladany, Stygar, Dominika, Katarzyna Nabrdalik, Tomasz Menżyk, Dorota Hudy, Derra, Aleksandra, Anastasios Koulaouzidis   +23 more
core   +1 more source

Circulating irisin levels are positively associated with metabolic risk factors in sedentary subjects. [PDF]

PLoS ONE, 2015
A physically active life-style plays an independent role in the protection against type 2 diabetes and cardiovascular diseases. Irisin, a novel exercise-induced myokine, activates thermogenesis in rodents through increasing beige fat cells abundance ...
María Moreno, José María Moreno-Navarrete, Marta Serrano, Francisco Ortega, Elías Delgado, Cecilia Sanchez-Ragnarsson, Sergio Valdés, Patricia Botas, Wifredo Ricart, José Manuel Fernández-Real   +9 more
doaj   +1 more source

Irisin Controls Growth, Intracellular Ca2+ Signals, and Mitochondrial Thermogenesis in Cardiomyoblasts. [PDF]

PLoS ONE, 2015
Exercise offers short-term and long-term health benefits, including an increased metabolic rate and energy expenditure in myocardium. The newly-discovered exercise-induced myokine, irisin, stimulates conversion of white into brown adipocytes as well as ...
Chao Xie, Yuan Zhang, Tran D N Tran, Hai Wang, Shiwu Li, Eva Vertes George, Haoyang Zhuang, Peilan Zhang, Avi Kandel, Yimu Lai, Dongqi Tang, Westley H Reeves, Henrique Cheng, Yousong Ding, Li-Jun Yang   +14 more
doaj   +1 more source