Results 31 to 40 of about 962,396 (163)
EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth
Journal of Hematology & Oncology, 2017 Background Activated protein C/endothelial protein C receptor (APC/EPCR) axis is physiologically involved in anticoagulant and cytoprotective activities in endothelial cells.
Naiara Perurena +11 more
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Current Issues in Molecular Biology, 2022 An important goal of biological research is to explain and hopefully predict cell behavior from the molecular properties of cellular components. Accordingly, much work was done to build extensive “omic” datasets and develop theoretical methods, including
Pierre Bongrand
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A role for Rap2 in recycling the extended conformation of LFA-1 during T cell migration
Biology Open, 2012 Summary T lymphocytes make use of their major integrin LFA-1 to migrate on surfaces that express ICAM-1 such as blood vessels and inflamed tissue sites.
Paula Stanley, Sharon Tooze, Nancy Hogg
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Diagnostics, 2020 Septic shock/severe sepsis is a deregulated host immune system response to infection that leads to life-threatening organ dysfunction. Lung inflammation as a form of acute lung injury (ALI) is often induced in septic shock.
Yuichi Akama +7 more
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Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1
Communications Biology, 2023 Scribble (Scrib) is a multidomain polarity protein and member of the leucine-rich repeat and PDZ domain (LAP) protein family. A loss of Scrib expression is associated with disturbed apical-basal polarity and tumor formation.
Eva-Maria Thüring +9 more
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Unraveling T-cell decoding strategy: a step forward
The EMBO JournalElucidation of the mechanisms by which T-cells discriminate between self and foreign antigens has been a major challenge in immunology. In this issue of The EMBO Journal, Huhn and colleagues (Huhn et al, 2025) show that the affinity between soluble ...
Philippe Robert, Pierre Bongrand
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Depth profile of thin coating through surface and interfacial cutting analysis of UV curing system
Materials & Design, 2019 There are various thin coating technologies, among which the UV coating technology is attracting attention in next-generation industries. In order to utilize the UV coating system stably, it is necessary to analyze and address the problems of surface ...
Ji-Won Park +6 more
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Nature CommunicationsTalin regulates crucial cellular functions, including cell adhesion and motility, and affects human diseases. Triggered by mechanical forces, talin plays crucial roles in facilitating the formation of focal adhesions and recruiting essential focal ...
Erumbi S. Rangarajan +3 more
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Gap junction-mediated regulation of endothelial cellular stiffness
Scientific Reports, 2017 Endothelial monolayers have shown the ability to signal each other through gap junctions. Gap junction-mediated cell-cell interactions have been implicated in the modulation of endothelial cell functions during vascular inflammation.
Takayuki Okamoto +7 more
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Frontiers in Medicine, 2020 Numerous factors affecting the interactions between healthcare professionals in the workplace demand a comprehensive understanding if the quality of patient healthcare is to be improved.
Eiji Kawamoto +7 more
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