Results 101 to 110 of about 673,565 (309)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

OPTIMIZATION OF THE RHEOLOGICAL PARAMETERS OF PILOT LIQUID DOSAGE FORMS IN THE DEVELOPMENT OF SPRAY PREPARATION AND TECHNOLOGY FOR ORAL CAVITY DISEASES TREATMENT

open access: yesРазработка и регистрация лекарственных средств, 2019
Theoretically substantiated and experimentally determined viscosity and adhesive properties of the experimental compositions of the liquid formulation with plant extracts of Eucalyptus (evkalimin) and Echinacea purpurea (estifan).
P. G. Mizina   +6 more
doaj  

Dot patterns provide reproducible flaw areas for study of adhesive bonds [PDF]

open access: yes, 1966
Photographic production of a small-dot pattern of known geometry on the surface of a substrate for controlled area degradation enables a study of adhesive bond strengths.
Frank, L., Schmitz, G.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Can a Novel Device with Pure Dry Air Increase the Shear Bond Strength of Dental Composites to Dentin? An Experimental Study

open access: yesDentistry Journal
Modern conservative dentistry is taking the lead in daily clinical practice and is relying on adhesion. Whether it is a simple composite, ceramic inlays, onlays, veneers or crowns, the common factor for a successful outcome is a good bonding of these ...
Khalil Kharma   +7 more
doaj   +1 more source

Nondestructive testing of adhesive bonds by nuclear quadrupole resonance method [PDF]

open access: yes, 1971
Inert, strain sensitive tracer, cuprous oxide, added to polymeric adhesive ensures sufficiently large signal to noise ratio in NQR system output. Method is successful, provided that RF-transparent structural materials are used between modified adhesive ...
Hewitt, R. R.
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Effect of debond growth on stress-intensity factors in a cracked orthotropic sheet stiffened by a semi-infinite orthotropic sheet [PDF]

open access: yes
Stress-intensity factors are determined for a cracked infinite sheet adhesively bonded to a stringer, and debonding of the adhesive layer is predicted. The stringer is modeled as a semi-infinite sheet. Adhesive nonlinearity is also included.
Bigelow, C. A.
core   +1 more source

Adhesive coating eliminated in new honeycomb-core fabrication process [PDF]

open access: yes, 1974
Technique eliminates use of silicone-based adhesive material as bonding medium. Adhesive requires precise time-temperature cure. Prepreg resin is used as bonding medium, and each layer is laminated together to form honeycomb billet.
Batty, W. L., Hayes, R. H., Magee, F. S.
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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