Results 101 to 110 of about 140,767 (331)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Cell contacts and pericellular matrix in the Xenopus gastrula chordamesoderm.
PLoS ONEConvergent extension of the chordamesoderm is the best-examined gastrulation movement in Xenopus. Here we study general features of cell-cell contacts in this tissue by combining depletion of adhesion factors C-cadherin, Syndecan-4, fibronectin, and ...
Olivia Luu +2 more
doaj +1 more source
Adhesive Durability Inside the Root Canal Using Self-adhesive Resin Cements for Luting Fiber Posts [PDF]
, 2017 Kerstin Bitter +5 more
openalex +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
FoodsTexture-modified diets (TMDs) are a primary compensatory treatment for hospitalized older patients with swallowing and mastication disorders. Nevertheless, the lack of a protocol for evaluating their objective textural properties hampers their ...
Kovan Ismael-Mohammed +4 more
doaj +1 more source
Breeding for improved tuber quality in greater yam (Dioscorea alata L.) [PDF]
, 2018 Yams constitute an important staple food in tropical and subtropical regions. Dioscorea alata is one of the major cultivated species with a wide geographical distribution. It is currently second to D. rotundata in terms of production volume.
Arnau, Gemma +7 more
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Low cytotoxic tissue adhesive based on oxidized dextran and epsilon‐poly‐
, 2013 Suong‐Hyu Hyon +3 more
openalex +1 more source