Results 81 to 90 of about 29,276 (300)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Studies Concerning Heat-Resisting Additives for Bitumens [PDF]

Bulletin of the Polytechnic Institute of Jassy: Constructions, Architechture Section, 2008
The improvement of causeway’s bitumen adhesiveness is becoming a current practice in our country, especially when is used acid (siliceous) aggregate.
Livia Groll, I. Hîrhui, Loredana Judele
doaj  

Formulation of nicotine mucoadhesive tablet for smoking cessation and evaluation of its pharmaceuticals properties

Advanced Biomedical Research, 2013
Background: Nicotine replacement therapy (NRT) with gradual decreasing of nicotine is one of the smoking cessation methods. Muccoadhesive formulations are among the novel drug delivery systems that are available in the form of tablets and films, and can ...
Rahim Bahri-Najafi, Zahra Rezaei, Mohammad Peykanpour, Leyla Shabab, Reza Solooki, Pooya Akbari   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Platelet adhesiveness: A possible link between the lipid and thrombogenic theories of atheroma production [PDF]

, 1970
The main aim of the thesis is the investigation of the relationships between platelet adhesiveness and serum lipids in vivo. If it were possible to link these then the platelet would become a bridge between the lipid and thrombogenic theories of atheroma
Fyfe, Thomas
core  

Rheological properties of thickening products that provide the therapeutic effect on safety and efficacy of swallow in patients with post-stroke oropharyngeal dysphagia

Food Science and Human Wellness
IntroductionFluid thickening improves safety of swallow in patients with oropharyngeal dysphagia due to shear, extensional and/or textural properties.
Mireia Bolivar-Prados, Adrian Nuñez-Lara, Kovan Ismael-Mohammed, Jordi Belda-de Vial, Claudia Arenas, Pere Clave   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A methodological approach to assess the ropy character of stirred acid dairy gels based on the measure of adhesiveness

JDS Communications
This work aims to evaluate the potential and limits of adhesiveness measurement using a texturometer to assess the ropiness of acid dairy gels for starter selection.
Siwar Nahali, Audrey Gilbert, Charlotte Marchand, Marie-Hélène Lessard, Donna Miller, Sébastien Fraud, Steve Labrie, Sylvie L. Turgeon   +7 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Strain-induced Orientation Response of Endothelial Cells: Effect of Substratum Adhesiveness and Actin-myosin Contractile Level [PDF]

, 2008
Endothelial cells subjected to cyclic stretching change orientation so as to be aligned perpendicular to the direction of applied strain in a magnitude and time-dependent manner.
Sara J. Oswald, Hai Ngu, Lan Lu, Sarah Davis, Sumona Nag, Frank C-P Yin   +5 more
core   +2 more sources