Results 101 to 110 of about 29,276 (300)

New paste for severe stomatitis in patients undergoing head-and-neck cancer radiotherapy and/or chemotherapy with oral appliance

BMC Cancer, 2018
Background The aim of the present study was to evaluate the physical properties of “admixture paste”, which is a commercially available gel containing hinokitiol for use against severe stomatitis, and its characteristics as a moisturizing gel and denture
Ayumi Sakuramoto, Yoko Hasegawa, Kazuma Sugahara, Yoshiyuki Komoda, Kana Hasegawa, Shinichi Hikasa, Mai Kurashita, Junya Sakai, Masahiro Arita, Kazuhiro Yasukawa, Hiromitsu Kishimoto   +10 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Platelet adhesiveness and plasma fibrinogen in acute myocardial infraction. [PDF]

, 1981
The work involves the study of 32 patients with acute myocardial infarction and 15 patients’ controls to demonstrate the presence of a hypercoagulable state by doing platelet adhesiveness and plasma fibrinogen levels in such cases. It reveals that
Gul Bano (Scholar), Miraj-ud-Din (Guide)
core  

Screen filtration pressure method and adhesiveness and aggregation of blood cells [PDF]

, 1964
An apparatus is described which measures the resistance to flow of blood through a screen with multiple openings 20 μ square. This apparatus is especially sensitive to presence in blood of aggregated blood elements and adhesive materials.
Roy L. Swank, Jerold Jansen, John G. Roth   +2 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Correlation between corneal adhesiveness and traditional tear tests for each group of participants. [PDF]

, 2014
The values of corneal adhesiveness were plotted on the X-axis as follows: 1 =  poor, 2 =  fair, 3 =  borderline, 4 =  excellent. Vital staining is plotted as follows: 0 =  panel A (grade = 1), 1 = panel B (grade 2), 2 = panel C (grade 3), 3 = panel D ...
Giovanni Maria Satta (654619), Franco Coronella (654618), Maria Silvana Galantuomo (678471), Pietro Emanuele Napoli (654617), Maurizio Fossarello (631571)   +4 more
core   +1 more source

Cell contacts and pericellular matrix in the Xenopus gastrula chordamesoderm.

PLoS ONE
Convergent extension of the chordamesoderm is the best-examined gastrulation movement in Xenopus. Here we study general features of cell-cell contacts in this tissue by combining depletion of adhesion factors C-cadherin, Syndecan-4, fibronectin, and ...
Olivia Luu, Debanjan Barua, Rudolf Winklbauer   +2 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Exploring Texture and Biomechanics of Food Oral Processing in Fork-Mashable Dishes for Patients with Mastication or Swallowing Impairments

Foods
Texture-modified diets (TMDs) are a primary compensatory treatment for hospitalized older patients with swallowing and mastication disorders. Nevertheless, the lack of a protocol for evaluating their objective textural properties hampers their ...
Kovan Ismael-Mohammed, Mireia Bolívar-Prados, Laura Laguna, Adrian Nuñez Lara, Pere Clavé   +4 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source