Results 61 to 70 of about 140,767 (331)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

A Perspective of Coagulation Dysfunction in Multiple Sclerosis and in Experimental Allergic Encephalomyelitis [PDF]

open access: yes, 2018
A key role of both coagulation and vascular thrombosis has been reported since the first descriptions of multiple sclerosis (MS). Subsequently, the observation of a close concordance between perivascular fibrin(ogen) deposition and the occurrence of ...
Adams   +158 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

A Scalable Method to Fabricate 2D Hydrogel Substrates for Mechanobiology Studies with Independent Tuning of Adhesiveness and Stiffness

open access: yesMethods and Protocols
Mechanical signals from the extracellular matrix are crucial in guiding cellular behavior. Two-dimensional hydrogel substrates for cell cultures serve as exceptional tools for mechanobiology studies because they mimic the biomechanical and adhesive ...
Alessandro Gandin   +3 more
doaj   +1 more source

Does chewing xylitol gum improve oral health? [PDF]

open access: yes, 2013
Popular chewing gum brands such as Orbit and Trident advertise that chewing their gum promotes oral health due to the presence of xylitol. This compound has interested oral health researchers since the 1970 s, but recent advances in research have been ...
Rouse, Thomas
core   +2 more sources

Gel Formulation of Ethanol Extract of Mangosteen Peel (Garcinia Mangostana L.) as a Medication for Burns in Wistar Rats [PDF]

open access: yes, 2017
Background: Mangosteen peel (Garcinia mangostana L.) has been shown to stimulate the regeneration of damaged body cells and have an antimicrobial activity that can be beneficial in healing burns.
Sugihartini, N. (Nining)   +1 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Evaluation of the adhesive properties of the cornea by means of optical coherence tomography in patients with meibomian gland dysfunction and lacrimal tear deficiency. [PDF]

open access: yesPLoS ONE, 2014
The aim was to determine the influence of meibomian gland dysfunction (MGD) and aqueous tear deficiency dry eye (ADDE) on the adhesive properties of the central cornea by means of optical coherence tomography (OCT), and to investigate the relationship ...
Pietro Emanuele Napoli   +4 more
doaj   +1 more source

Special Adaptations of Orb Weavers and Prey [PDF]

open access: yes, 1986
Orb weaving spiders have devised both webs and special devices for capturing prey. The prey have also evolved mechanisms for eluding spiders and for living with them.
Dorris, Peggy Rae
core   +2 more sources

An overview about erythrocyte membrane [PDF]

open access: yes, 2010
© 2010 – IOS Press and the authors. All rights reservedIn the sixties and seventies, erythrocytes or red blood cells (RBCs) were extensively studied. Much has been learnt particularly concerning their metabolism and gas transporter function. In the past
Oliveira, Sofia de, Saldanha, Carlota
core   +1 more source

Home - About - Disclaimer - Privacy