Results 71 to 80 of about 121,813 (264)

Development of low cost, high reliability sealing techniques for hybrid microcircuit packages, phase 2 [PDF]

open access: yes
Adhesives were evaluated to determine if they qualify for application to hybrid microcircuit packages. The effort consisted of the following: (1) seal gold-plated Kovar packages with selective adhesives and determine seal integrity after exposure to ...
Licari, J. J., Perkins, K. L.
core   +1 more source

Plastics: physical-and-mechanical properties and biodegradable potential [PDF]

open access: yes, 2020
Introduction. Processing agricultural waste into plant biodegradable plastics is a promising way for its recycling. This work featured the main physical-and-mechanical properties of plant plastics without adhesive substances obtained from millet husk and
Artyemov, A. V.   +5 more
core  

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Evaluation of a metering, mixing, and dispensing system for mixing polysulfide adhesive [PDF]

open access: yes
Tests were performed to evaluate whether a metered mixing system can mix PR-1221 polysulfide adhesive as well as or better than batch-mixed adhesive; also, to evaluate the quality of meter-mixed PR-1860 and PS-875 polysulfide adhesives.
Evans, Kurt B.
core   +1 more source

Elastomer toughened polyimide adhesives [PDF]

open access: yes, 1985
A rubber-toughened, addition-type polyimide composition is disclosed which has excellent high temperature bonding characteristics in the fully cured state and improved peel strength and adhesive fracture resistance physical property characteristics.
St.clair, A. K., St.clair, T. L.
core   +1 more source

Friction and Adhesion

open access: yes, 2006
The studies carried out on adhesion by the group “Modeling in Contact Mechanics” at the LMA are reviewed in this paper and recent applications are presented. Based on the introduction of the adhesion intensity variable developed by M. Frémond, different forms of a model coupling adhesion to unilateral contact and friction have been developed.
openaire   +6 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Quantitative analysis of the debonding structure of soft adhesives

open access: yes, 2013
We experimentally investigate the growth dynamics of cavities nucleating during the first stages of debonding of three different model adhesives. The material properties of these adhesives range from a more liquid-like material to a soft viscoelastic ...
Creton, Costantino   +3 more
core   +1 more source

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