Results 171 to 180 of about 52,972 (211)

Body Composition Phenotypes and Their Metabolic Associations in Treatment‐Naïve Patients With Newly Diagnosed Type 2 Diabetes: A DXA‐Based Cluster Analysis

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.
Using dual‐energy X‐ray absorptiometry clustering of 185 treatment‐naïve type 2 diabetes patients, we identified four body‐composition phenotypes. Central‐obesity and high‐fat–high‐muscle clusters carried the highest fatty liver disease and hyperuricemia risk, whereas the low‐muscle cluster carried the highest osteoporosis risk.
Xintong Zhang, Rui Zhang, Tao Jiang
wiley   +1 more source

Association of the ADAMTS14 rs4747096 Polymorphism and C‐Reactive Protein Levels With Knee Osteoarthritis Severity: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims The rs4747096 polymorphism in the ADAMTS14 gene and C‐reactive protein (CRP) levels have been associated with knee osteoarthritis (KOA) severity; however, evidence from Vietnam remains limited. This study aimed to investigate the distribution of rs4747096 genotypes, assess CRP levels, and examine their associations with KOA
Quyen Phuong Tran Cao, Nga Thi Ngoc Pham, Kien Trung Nguyen   +2 more
wiley   +1 more source

Residential exposures associated with adiposity and proinflammatory markers in obese adults with metabolic syndrome: a cross-sectional study. [PDF]

Arh Hig Rada Toksikol
Dzhambov AM, Kitov S, Kostadinov KR, Kitova MF, Burov A, Helbich M, Deneva T, Kitova L.   +7 more
europepmc   +1 more source

Leptin Neutralization Attenuates Inflammaging in Endothelial and Immune Cell Models

MedComm, Volume 7, Issue 11, November 2026.
Multiple mechanisms including senescent cell accumulation, metabolic and endotoxin‐driven stimulation of immune and endothelial cells contribute to inflammaging, the chronic low‐grade inflammatory status underlying age‐related diseases. Blocking leptin signaling in experimental models of inflammaging blunts inflammation in a model‐specific manner while
Valeria Pellegrini, Rosalba La Grotta, Alessia Metallo, Francesca Carreras, Chiara Frigé, Giulia Matacchione, Angelica Giuliani, Jacopo Sabbatinelli, Fabiola Olivieri, Francesca Rispoli, Lorenzo Drago, Cesare Celeste Berra, Raffaele Marfella, Giuseppe Paolisso, Giuseppe Matarese, Claudio Procaccini, Ilaria Spatocco, Giorgia Mele, Paola de Candia, Antonio Ceriello, Francesco Prattichizzo   +20 more
wiley   +1 more source

Short‐ and Long‐Term Control of Hypertension After Bariatric Surgery: A 10‐Year Prospective Study

MedComm, Volume 7, Issue 11, November 2026.
ABSTRACT Current guidelines support bariatric surgery (BS) as an effective treatment mainly for patients with severe obesity and poorly controlled hypertension. However, evidence in non‐severely obese Asian populations remains limited. This multicenter prospective cohort study included 248 Chinese patients with obesity and hypertension who underwent BS
Xiaoxiao Zhong, Yaoquan Cao, Xulong Sun, Pengzhou Li, Weizheng Li, Hong Yuan, Shaihong Zhu, Liangping Wu, Hua Meng, Yao Lu, Liyong Zhu   +10 more
wiley   +1 more source

Exercise-responsive endocrine-metabolic mediators in diabetes and cardiometabolic disorders: a systematic scoping review and evidence map. [PDF]

Front Endocrinol (Lausanne)
Zhao Z, Zhang Y, Liu Z, Li Q, Pan T, Yang S, Wang X, Song L, Li Z, Zhang R, Hou Z.   +10 more
europepmc   +1 more source

Protecting CEACAM1 Expression Prevents Diet‐Induced Metabolic Dysfunction and Hepatic Fibrosis in Male Mice

Obesity, Volume 34, Issue 11, Page 2094-2108, November 2026.
ABSTRACT Objective High‐fat diet represses Ceacam1 transcription via a PPARα‐mediated mechanism to cause insulin resistance before inflammation develops. The current study investigated whether mutating PPRE‐RXRα in Ceacam1 promoter prevents diet‐induced metabolic abnormalities and hepatic fibrosis in male C57BL6/J mice.
Raziyeh Abdolahipour, Saja S. Khuder, William M. Philbrick, Agnes O. Portuphy, Getachew D. Belew, Hatem G. Fallouh, Harrison T. Muturi, Boyeon Kim, Jason K. Kim, Sonia M. Najjar   +9 more
wiley   +1 more source

Role of certain adipokines in the pathophysiology of hypertension. [PDF]

Front Physiol
Yilmaz A, Obay BD, Ekinci A.
europepmc   +1 more source

Pharmacological and Therapeutic Potential of Garlic (Allium sativum): Integrating Phytochemistry, Molecular Mechanisms, and Clinical and Preclinical Evidence

ChemistryOpen, Volume 15, Issue 11, November 2026.
Garlic bioactive compounds, including organosulfur compounds (allicin, DADS, DATS, and SAC), phenolic compounds, and quercetin, regulate the Nrf2/HO‐1, NF‐κB, PI3K/Akt, and AMPK/eNOS signaling pathways. These actions enhance antioxidant defenses, suppress inflammation, improve metabolic and cardiovascular function, and contribute to reduced blood ...
Gudisa Bereda
wiley   +1 more source

Circulating Ghrelin, Nesfatin-1, and Vaspin Levels Across Glycemic Control Categories in Type 2 Diabetes Mellitus: A Cross-Sectional Study. [PDF]

Biomedicines
Akkus S, Saricam O, Kavruk M, Sariyildiz GT, Benguboz FB, Sirin BY, Altuner EE, Dursun AD, Ozalp VC.   +8 more
europepmc   +1 more source