Results 191 to 200 of about 99,913 (245)

Lipoedema and Obesity Misclassification: A Phenotype Based Approach to Cardiometabolic Risk Beyond Body Mass Index

Clinical Obesity, Volume 16, Issue 5, October 2026.
Clinical recognition of the lipoedema phenotype and principal differential diagnoses. ABSTRACT Lipoedema is a painful adipose tissue disorder marked by disproportionate limb fat and often misclassified as generalized obesity or lymphoedema. This review examines its metabolic phenotype and implications for cardiometabolic assessment and management ...
Ron T. Varghese, Diana G. Varghese
wiley   +1 more source

Adipocytes as a Mechanistic Link Between Incretin-Based Therapies and Hair Loss. [PDF]

Biology (Basel)
Gupta AK, Kaur J, Piguet V, Mirmirani P.
europepmc   +1 more source

Association of Serum Adiponectin, Sleep Quality, and Health-promoting Lifestyle with Metabolic Syndrome in Patients with Schizophrenia. [PDF]

Indian J Psychol Med
Makwana SR, Nebhinani N, Singh P, Yadav D, Raj AB.   +4 more
europepmc   +1 more source

Seminal Extracellular Vesicles as Molecular Modulators of Male Reproductive Function

Reproduction in Domestic Animals, Volume 61, Issue S3, October 2026.
ABSTRACT Extracellular vesicles (sEVs) contained in seminal plasma (SP) maintain, in concert with free SP‐components (proteins, hormones, cytokines, metabolites and antioxidants) under an endocrine umbrella the functional in vivo homeostasis of ejaculated spermatozoa. The sEVs define a generic mixture of nanovesicles delivered by male epithelial cells,
Heriberto Rodriguez‐Martinez, Jordi Roca, Fernando Peña Vega, Emilio A. Martinez   +3 more
wiley   +1 more source

A Novel Small-Molecule Dual Adiponectin Receptor 1/2 Agonist Induces Myogenesis and Ameliorates Skeletal Muscle Atrophy. [PDF]

J Cachexia Sarcopenia Muscle
Das S, Awasthi P, Moin MR, Pal S, Talukdar A, Kumar A, Nikolas N, Varode SS, Khatoon S, Das N, Chattopadhyay S, Mugale MN, Guha R, Sanyal S, Goel A.   +14 more
europepmc   +1 more source

Metformin Inhibits Trophoblast Ferroptosis by Suppressing ATF2 and Activating the PI3K/Akt/Nrf2 Pathway to Improve Gestational Diabetes Mellitus

The FASEB Journal, Volume 40, Issue 18, 30 September 2026.
Metformin suppresses ATF2 expression, activating the PI3K/Akt pathway and promoting Nrf2 nuclear translocation. This upregulates GPX4, inhibiting ferroptosis in trophoblast cells. Erastin blocks system Xc−, depleting GSH and promoting ferroptosis. LY294002 and ML385 inhibit the pathway, validating the mechanism.
Dandan Xia, Yuhui Zhang, Wenjie Liu, Siyu Li, Chenying Zhang, Guangtong She, Huiyan Wang   +6 more
wiley   +1 more source

High molecular weight adiponectin as an adjunct biomarker for insulin dysregulation in equids. [PDF]

J Vet Intern Med
de Laat MA, Fitzgerald DM, Li FI, Li FI, Sillence MN, McGree JM.   +5 more
europepmc   +1 more source

METTL18 is Required for Developmental, Metabolic, and Endocrine Regulation of Mammalian Growth

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
METTL18 is essential for histidine Nτ‐methylation of proteins, normal embryonic development, iron and lipid metabolism, and hormone signaling pathways that support postnatal growth in mice. The main points of this study are as follows: First, mouse METTL18 catalyzes histidine Nτ‐methylation. Next, Mettl18 KO embryos are significantly smaller than their
Fumiya Kasai, Jun‐Dal Kim, Koichiro Kako, Naoto Muromachi, Takeru Saito, Yao Yuan, Hayase Mizukami, Nana Kishikawa, Kanako Nakamura, Kaori Motomura, Hiroaki Daitoku, Yuuki Imai, Sho Sekiguchi, Kazuhiko Horiguchi, Satoshi Narumi, Masanobu Yamada, Akiyoshi Fukamizu   +16 more
wiley   +1 more source

Selective Small-Molecule AdipoR1 Agonist 3-Hydroxy Pterocarpan Salt (CDRI-1709S) Ameliorates Skeletal Muscle Atrophy. [PDF]

J Cachexia Sarcopenia Muscle
Moin MR, Pal S, Das S, Awasthi P, Talukdar A, Kumar A, Varode SS, Nikolas N, Khatoon S, Mugale MN, Guha R, Sanyal S, Goel A.   +12 more
europepmc   +1 more source

AdipoRon, an Adiponectin Receptor Agonist, Promotes Intestinal Epithelial Differentiation in Caco-2 Colorectal Adenocarcinoma Cells. [PDF]

Biomedicines
Mallardo M, Memon F, D'Auria L, Pagliaro R, Daniele A, Nigro E.   +5 more
europepmc   +1 more source