Results 181 to 190 of about 99,913 (245)

Immune cells in the pathogenesis of abdominal aortic aneurysm: Roles, regulation and targeted interventions

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review provides a comprehensive overview of how macrophages, neutrophils, T cells and other immune cells infiltrate the aortic wall, undergo phenotypic shifts and interact with one another in abdominal aortic aneurysm (AAA). Background Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease with no approved clinical drugs. Immune
Junqi Peng, Hanqing Zhang, Yun Wu, Song Chen   +3 more
wiley   +1 more source

Divergent responses of adiponectin and leptin to exercise in women with overweight or obesity: a systematic review and meta-regression. [PDF]

Front Physiol
Yuan X, Bao C, Feng X.
europepmc   +1 more source

Markers of Systemic Metabolic Dysfunction in Vitiligo and Their Potential Role in Disease Pathogenesis: A Narrative Review

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Vitiligo is a chronic autoimmune disease characterized by the progressive destruction of melanocytes, resulting in depigmented skin macules. While traditionally viewed as a cutaneous disorder driven by a specific CD8+ T cell‐mediated interferon‐γ (IFN‐γ) signature, emerging research suggests that vitiligo may be a systemic condition
Federica Papaccio, Simona Scano, Barbara Bellei   +2 more
wiley   +1 more source

Molecular and Cellular Underpinnings of Primary Hypertension: An Integrative Mechanistic Framework

Journal of Cellular Physiology, Volume 241, Issue 10, October 2026.
ABSTRACT Hypertension is a highly prevalent clinical condition and a major contributor to global cardiovascular morbidity and mortality. Despite extensive research, its complex and multifaceted pathogenesis is yet to be fully elucidated. This paper explores the updated understanding of primary hypertension as a systemic disorder rather than an isolated
Dima Nasrallah, Alaa Abdelhamid, Omar Tluli, Yaman Al‐Haneedi, Mera Abu Hussien, Ali H. Eid   +5 more
wiley   +1 more source

Associations of actigraphic sleep parameters with adipokines in older adults in the Baltimore longitudinal study of aging. [PDF]

Sleep Adv
Wei Z, Yue Y, Rabinowitz JA, Kaizi-Lutu M, Wu MN, Chia CW, Tanaka T, Simonsick EM, Ferrucci L, Spira AP.   +9 more
europepmc   +1 more source

Predictors of Liver Steatosis Progression Among People Living With HIV in Low‐ and Middle‐Income Countries: A Multicentre Longitudinal Study

Journal of the International AIDS Society, Volume 29, Issue 10, October 2026.
ABSTRACT Introduction Liver steatosis is increasingly recognized as a major comorbidity in people living with HIV (PLWH), with growing evidence suggesting an increased risk of progression to advanced liver disease. We assessed predictors of liver steatosis progression over 36 months in PLWH from low‐ and middle‐income countries.
Marie K. Plaisy, Thierry Tiendrebeogo, Carlotta Mondoka, Mark H. Kuniholm, Rodrigo de Carvalho Moreira, Aggrey Semeere, Rohidas T. Borse, Albert Minga, Gilles Wandeler, Gad Murenzi, Brenda E. Crabtree‐Ramírez, Niharika Samala, Jeremy Ross, Ephrem Mensah, Ardele Mandiriri, Sandra W. Cardoso, Jean Paul Mivumbi, Lameck Diero, Haridas Prasad, Paola Alarcón Murra, Belinda V. Chihota, Suzanne Goodrich, Thida Chanyachukul, Ellen Brazier, Stephany N. Duda, Hugo Perazzo, Antoine Jaquet, the International epidemiology Databases to Evaluate AIDS (IeDEA)   +27 more
wiley   +1 more source

Adipokine, endocrine, and fibrinolysis-related alterations across abdominal obesity and metabolic syndrome phenotypes in young adults. [PDF]

Front Endocrinol (Lausanne)
Puhalo Sladoje D, Dragojević I, Bokonjić D, Zečević-Pašić L, Čančar O, Hasanefendić B, Kisić B.   +6 more
europepmc   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng, Yuanyuan Shen, Ying Sun, Lu Lu, Chongkui Sun   +4 more
wiley   +1 more source

Effects of gestational weight gain and HbA1C on fetal growth and birthweight in women with obesity

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 10, Page 1994-2004, October 2026.
Our results indicate that HbA1C measured in the third semester and the modifiable gestational weight gain are exposures with the potential to influence fetal growth and birthweight in this population of pregnant women with pBMI ≥35 kg/m2. Abstract Introduction Fetal growth and birthweight are influenced by various endogenous and exogenous factors ...
Maja Lecic Bonnichsen, Elisabeth Qvigstad, Lill Trine Nyfløt, Guttorm Haugen, William R. P. Denault, Marie Cecilie Roland   +5 more
wiley   +1 more source

Adipose tissue depots and blood pressure regulation: mechanisms, biomarkers, and targets beyond obesity. [PDF]

Am J Hypertens
Rodriguez S, Kamalumpundi V, Peterson J, Tucker C, Cheng L, Shams E, Meyers E, Jawadi S, Pereira RO, Correia MLG.   +9 more
europepmc   +1 more source