Age-related adiponectin resistance in human skeletal muscle dysfunction: in vivo and in vitro evidence. [PDF]
Surina S +15 more
europepmc +1 more source
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
Epigenome-wide analysis in West Africans identifies DNA methylation markers for circulating adiponectin. [PDF]
Mungamba MM +14 more
europepmc +1 more source
Does Gum Arabic Alter Gene Expression? Diabetic and Obesity as Models: A Mini Review
Gum Arabic (GA) modulates obesity‐ and diabetes‐related gene expression, reducing pro‐inflammatory cytokines (IL‐6, TNF‐α, IL‐1β) and increasing IL‐10. GA elevates pAMPK, pACC, and GLP‐1 while decreasing FASN and leptin, indicating improved energy and lipid metabolism. Oxidative stress markers (SOD, GPx, CAT) rise with GA, alongside increased GLUT3 and
Saber Y. Adam +4 more
wiley +1 more source
Adiponectin Inhibits Oxidative Stress and Tight Junction Protein Loss: Evidence from a Hepatic Encephalopathy Mouse Model and Brain Endothelial Cells. [PDF]
Song DJ +7 more
europepmc +1 more source
Adiponectin as a Predictor of Metabolic Dysfunction-Associated Steatotic Liver Disease and Non-Alcoholic Fatty Liver Disease: A 17-Year Korean Cohort Study (Diabetes Metab J 2026;50:331-42). [PDF]
Jiang G, Wang G.
europepmc +2 more sources
ABSTRACT Background Autophagy is an evolutionarily highly conserved process and plays an important role in cellular homeostasis and metabolism. In obesity and obesity‐associated insulin resistance, both enhanced and suppressed autophagy have been observed in adipose tissues (AT).
Edita Islami +5 more
wiley +1 more source
Impact of Obesity on Systemic Treatment Outcomes in Metastatic Urological Malignancies
ABSTRACT Introduction Obesity increasingly influences treatment outcomes in urological malignancies (metastatic bladder cancer (BC), renal cell cancer (RCC), and prostate cancer (PC)). This study evaluated the impact of obesity on survival in patients with major metastatic urological cancers receiving systemic therapy.
A. Handke +7 more
wiley +1 more source
Adiponectin and aging: Mechanistic insights, clinical paradox, and therapeutic horizons. [PDF]
McGregor ER +5 more
europepmc +1 more source

