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Adiponectin and Adiponectin Receptors [PDF]

Endocrine Reviews, 2005
Metabolic syndrome is thought to result from obesity and obesity-linked insulin resistance. Obesity in adulthood is characterized by adipocyte hypertrophy. Adipose tissue participates in the regulation of energy homeostasis as an important endocrine organ that secretes a number of biologically active "adipokines."Heterozygous peroxisome proliferator ...
Motohiro Sasaki, Toshimasa Yamauchi, Yamauchi Toshimasa   +2 more
exaly   +3 more sources

Adiponectin and Adiponectin Receptors in Atherosclerosis

Endocrine Reviews
Abstract Adiponectin is an abundantly secreted hormone that communicates information between the adipose tissue, and the immune and cardiovascular systems. In metabolically healthy individuals, adiponectin is usually found at high levels and helps improve insulin responsiveness of peripheral tissues, glucose tolerance, and fatty acid ...
, , Daskalopoulou Stella S
exaly   +3 more sources

Polymorphism in Adiponectin and Adiponectin Receptor Genes in Diabetes Mellitus Pathogenesis [PDF]

Pathophysiology, 2022
The role played by hereditary factors in the development of diabetes mellitus type 2 (DM2) has not yet been fully established. Therefore, the purpose of our study was to investigate the prevalence of adiponectin and polymorphism in its gene receptors in connection with the primary symptoms of DM2 pathogenesis.
Iuliana Shramko, Elizaveta Ageeva, Eugene Krutikov, Konstantin Maliy, Irina Repinskaya, Iryna Fomochkina, Anatolii Kubishkin, Anna Gurtovaya, Cyrill Tarimov, Suman Shekhar   +9 more
openaire   +3 more sources

Age Associated Changes In Transcription Of Adiponectin, AdipoR1 And AdipoR2 Genes In Pancreas Of Rats [PDF]

Cell Journal, 2020
Objective Adiponectin has a crucial role in the function, proliferation and viability of β-cell via action of two receptors: AdipoR1 and AdipoR2. Nevertheless, age related change of Adiponectin system genes in pancreas is unclear or controversial.
Marziyeh Feyzi, Mohammad Reza Tabandeh, Mehrdad Shariati, Edalatmanesh Mohammad Amin   +3 more
doaj   +1 more source

Adiponectin, Adiponectin Receptors, and Epigenetic Regulation of Adipogenesis [PDF]

Cold Spring Harbor Symposia on Quantitative Biology, 2011
We studied the molecular mechanism of obesity-induced insulin resistance and adipogenesis. Plasma adiponectin and adiponectin receptor (AdipoR1) in muscle are down-regulated in obesity. Analysis of muscle-specific AdipoR1 knockout mice revealed the pivotal role of adiponectin/AdipoR1 in the regulation of mitochondrial biogenesis via AMPK- and SIRT1 ...
T, Kadowaki, T, Yamauchi, H, Waki, M, Iwabu, M, Okada-Iwabu, M, Nakamura   +5 more
openaire   +2 more sources

Adiponectin modulates steroid hormone secretion, granulosa cell proliferation and apoptosis via binding its receptors during hens’ high laying period

Poultry Science, 2021
: Adiponectin is an important adipocytokine and plays the roles in multiple metabolic processes via binding its receptors - AdipoR1 and AdipoR2, which has also been found to participate in the regulation of the reproductive system of animals, in ...
Jing Li, Xue-Jie Ma, Xing Wu, Su-Jin Si, Chong Li, Peng-Kun Yang, Guo-Xi Li, Xiao-Jun Liu, Ya-Dong Tian, Xiang-Tao Kang   +9 more
doaj   +1 more source

Dimerization of adiponectin receptor 1 is inhibited by adiponectin [PDF]

Journal of Cell Science, 2010
AdipoR1 and AdipoR2 are newly discovered members of the huge family of seven-transmembrane receptors, but both receptors are structurally and functionally different from G-protein-coupled receptors. Little is known about the oligomerization of the AdipoRs.
David, Kosel, John T, Heiker, Cathleen, Juhl, Cornelia M, Wottawah, Matthias, Blüher, Karin, Mörl, Annette G, Beck-Sickinger   +6 more
openaire   +2 more sources

Correlation of Adiponectin mRNA Abundance and Its Receptors with Quantitative Parameters of Sperm Motility in Rams [PDF]

International Journal of Fertility and Sterility, 2016
Background Adiponectin and its receptors (AdipoR1 and AdipoR2), known as adiponectin system, have some proven roles in the fat and glucose metabolisms. Several studies have shown that adiponectin can be considered as a candidate in linking metabolism to ...
Ali Kadivar, Heidar Heidari Khoei, Hossein Hassanpour, Arefe Golestanfar, Hamid Ghanaei   +4 more
doaj   +1 more source

Effect of Exercise Training on Gene Expression of Adiponectin and its Receptors in Testicles and Sex Hormones in Diabetic Rats

Journal of Biological Research, 2021
Adiponectin and its receptors are expressed in the male reproductive system, which play a role in regulating male sex hormones and fertility. Diabetes was induced by Streptozotocin-Nicotinamide (STZ-NA i.p) in rats and after performing the trainings ...
Zahra Nadi, Mohammad Bayat, Hadi Karami, Mohamad Parastesh, ParvinDokht Bayat   +4 more
doaj   +1 more source

Adiponectin receptor signalling in the brain [PDF]

British Journal of Pharmacology, 2011
Adiponectin is an important adipocyte‐derived hormone that regulates metabolism of lipids and glucose, and its receptors (AdipoR1, AdipoR2, T‐cadherin) appear to exert actions in peripheral tissues by activating the AMP‐activated protein kinase, p38‐MAPK, PPARα and NF‐kappa B.
Thundyil, John, Pavlovski, Dale, Sobey, Christopher G., Arumugam, Thiruma V.   +3 more
openaire   +5 more sources