Results 11 to 20 of about 29,601 (261)

Adiponectin and adiponectin receptors in the mouse preimplantation embryo and uterus [PDF]

Human Reproduction, 2010
Adiponectin (Adipoq), a protein secreted by adipocytes in inverse proportion to the adipose mass present, modulates energy homeostasis and increases insulin sensitivity. Tissue Adipoq signaling decreases in settings of maternal diabetes, polycystic ovary syndrome (PCOS) and endometriosis, conditions which are associated with reproductive difficulty ...
S T, Kim, K, Marquard, S, Stephens, E, Louden, J, Allsworth, K H, Moley   +5 more
openaire   +2 more sources

Heat shock protein 60 (HSP60) modulates adiponectin signaling by stabilizing adiponectin receptor

Cell Communication and Signaling, 2020
Adiponectin, an adipokine produced and secreted by adipocytes, is involved in regulating the development and progression of insulin resistance, diabetes, and diabetic complications.
Deling Zhang, Hua Liu, Yemin Zhang, Junfeng Li, Yalin Fu, Yuyang Zheng, Jie Wu, Mingke Ma, Zhongyuan Wen, Changhua Wang   +9 more
doaj   +1 more source

Adiponectin and adiponectin receptor in relation to colorectal cancer progression [PDF]

International Journal of Cancer, 2010
AbstractAlthough obesity is a risk factor for colorectal cancer, the underlying mechanism is not clear. Adiponectin is an adipokine that binds to 2 types of receptors, AdipoR1 and AdipoR2. The plasma concentrations of adiponectin are reduced in obese individuals and adiponectin has been reported to have anticarcinogenic properties. Furthermore, AdipoR1
Jeong-Sik, Byeon, Jin-Yong, Jeong, Mi Jung, Kim, Sun-Mi, Lee, Won-Hee, Nam, Seung-Jae, Myung, Jae Gyu, Kim, Suk-Kyun, Yang, Jin-Ho, Kim, Dong Jin, Suh   +9 more
openaire   +2 more sources

Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome [PDF]

Journal of Clinical Investigation, 2006
Adiponectin is an adipokine that is specifically and abundantly expressed in adipose tissue and directly sensitizes the body to insulin. Hypoadiponectinemia, caused by interactions of genetic factors such as SNPs in the Adiponectin gene and environmental factors causing obesity, appears to play an important causal role in insulin resistance, type 2 ...
Takashi, Kadowaki, Toshimasa, Yamauchi, Naoto, Kubota, Kazuo, Hara, Kohjiro, Ueki, Kazuyuki, Tobe   +5 more
openaire   +2 more sources

Native adiponectin in serum binds to mammalian cells expressing T-cadherin, but not AdipoRs or calreticulin

eLife, 2019
Adiponectin is an adipocyte-derived atypically abundant circulating factor that protects various organs and tissues through its receptors, AdipoRs, calreticulin, and T-cadherin.
Shunbun Kita, Shiro Fukuda, Norikazu Maeda, Iichiro Shimomura   +3 more
doaj   +1 more source

Potential activity of adiponectin‐expressing regulatory T cells against triple‐negative breast cancer cells through the cell‐in‐cell phenomenon

Thoracic Cancer, 2023
Background A population of regulatory T cells (Treg), which reside within thymic nurse cell complexes, express adiponectin and abrogate breast cancer development in transgenic mice.
Wakana Chikaishi, Toshiya Higashi, Hirokatsu Hayashi, Yuki Hanamatsu, Yusuke Kito, Manabu Futamura, Nobuhisa Matsuhashi, Chiemi Saigo, Tamotsu Takeuchi   +8 more
doaj   +1 more source

Adiponectin levels and expression of adiponectin receptors in isolated monocytes from overweight patients with coronary artery disease

Cardiovascular Diabetology, 2011
Background Adiponectin has insulin-sensitizing and anti-atherosclerotic effects, partly mediated through its action on monocytes. We aimed to determine adiponectin levels and expression of its receptors (AdipoR1 and AdipoR2) in peripheral monocytes from ...
Economopoulos Theofanis, Lekakis John, Boutati Eleni, Kyriazi Erifyli, Mitrou Panayota, Maratou Eirini, Ikonomidis Ignatios, Tsiotra Panayoula C, Kollias Anastasios, Kremastinos Dimitrios T, Dimitriadis George, Raptis Sotirios A   +11 more
doaj   +1 more source

High-fat diet and glucocorticoid treatment cause hyperglycemia associated with adiponectin receptor alterations

Lipids in Health and Disease, 2011
Background Adiponectin is the most abundant plasma protein synthesized for the most part in adipose tissue, and it is an insulin-sensitive hormone, playing a central role in glucose and lipid metabolism.
Oller do Nascimento Cláudia, Ribeiro Eliane B, Oyama Lila M, Biz Carolina, de Mattos Ana BM, de Oliveira Cristiane   +5 more
doaj   +1 more source

Adiponectin and Adiponectin Receptors in Human Pheochromocytoma

Journal of Atherosclerosis and Thrombosis, 2009
Recent studies have demonstrated that serum adiponectin and its receptors in adipose and muscle tissues are suppressed in diabetic or obese individuals. Patients with pheochromocytoma are frequently diabetic.Using real-time PCR, we examined mRNA expressions of adiponectin (Adp) and adiponectin receptor 1 (AdpR1) and AdpR2 in pheochromocytoma tissues ...
Isobe, Kazumasa, FU, Ling, Tatsuno, Ichirou, Takahashi, Hideto, Nissato, Sumiko, Hara, Hisato, Yashiro, Toru, Suzukawa, Kazumi, Takekoshi, Kazuhiro, Shimano, Hitoshi, Kawakami, Yasushi   +10 more
openaire   +3 more sources

Cardiovascular Adiponectin Resistance: The Critical Role of Adiponectin Receptor Modification [PDF]

Trends in Endocrinology & Metabolism, 2017
For the past two decades, a great deal of research has been published concerning adiponectin (APN), an abundant protein responsible for regulating numerous biologic functions including antioxidative, antinitrative, anti-inflammatory, and cardioprotective effects.
Yajing, Wang, Xin L, Ma, Wayne Bond, Lau
openaire   +2 more sources