Dietary strategies modulate the progression of diabetic cardiomyopathy by targeting oxidative stress, inflammation, mitochondrial dysfunction, and myocardial fibrosis. Specific nutrients and bioactive compounds, as well as caloric restriction, improve myocardial metabolism and redox balance, whereas ketogenic diets exert time‐dependent beneficial or ...
Wen‐hui Deng +9 more
wiley +1 more source
ADIPOQ polymorphisms and haplotypes affect circulating adiponectin levels and their association with gestational hypertension and preeclampsia. [PDF]
Fróes de Castro RN +8 more
europepmc +1 more source
Hyperglycemia Leads to BMSC Impaired Osteogenesis, Enhanced Adipogenesis, and Altered Metabolism
ABSTRACT Diabetes is a major risk factor for osteoporosis, which negatively impacts bone health, but the mechanisms underlying the effects of hyperglycemia on bone marrow mesenchymal/stromal cells (BMSC) are not fully understood. This study investigated how high glucose levels influence BMSC differentiation, proliferation, viability, and metabolism ...
Suzanna Shirazi +4 more
wiley +1 more source
Adipokines and mortality in burns and traumatic brain injury. [PDF]
Ma Y +3 more
europepmc +1 more source
Clock Modulation by Naringenin Suppresses Lipogenesis and Promotes Adipose Tissue Browning
ABSTRACT The circadian clock orchestrates adipocyte development and lipid remodeling, with its disruption leading to the development of obesity and insulin resistance. Here we demonstrate that the flavonoid compound naringenin displays clock modulatory activity that suppresses adipocyte lipid storage while promoting browning. In adipogenic progenitors,
Xuekai Xiong +6 more
wiley +1 more source
The anti-obesity effect of namodenoson, an A3 adenosine receptor agonist. [PDF]
Fishman P +5 more
europepmc +1 more source
The Effect of Low Socioeconomic Status on the Leptin-to-Adiponectin Ratio. [PDF]
Rausch J, Horne K, Marquez L.
europepmc +1 more source
Osteoarthritis: Epidemiology, Pathogenesis, and Treatment
Osteoarthritis is a prevalent degenerative joint disease with a growing global burden. Its development involves complex interactions among epidemiological factors, pathological changes, molecular signaling, and epigenetic regulation. Understanding these mechanisms provides insights into disease progression and supports the development of therapeutic ...
Tianrui Chen +8 more
wiley +1 more source
Metabolic dysfunction-associated steatotic liver disease, biomarkers, and cardiovascular risk factors in children with excess weight. [PDF]
Machado EA +12 more
europepmc +1 more source

